ATE82982T1 - Neue mittel dc-92b und dc-92d, sowie deren verfahren zur herstellung. - Google Patents
Neue mittel dc-92b und dc-92d, sowie deren verfahren zur herstellung.Info
- Publication number
- ATE82982T1 ATE82982T1 AT87904737T AT87904737T ATE82982T1 AT E82982 T1 ATE82982 T1 AT E82982T1 AT 87904737 T AT87904737 T AT 87904737T AT 87904737 T AT87904737 T AT 87904737T AT E82982 T1 ATE82982 T1 AT E82982T1
- Authority
- AT
- Austria
- Prior art keywords
- manufacture
- well
- actinomadura
- pref
- antibiotics
- Prior art date
Links
- SCWWNJYIUMBQKK-UHFFFAOYSA-N 10-[4-(dimethylamino)-5,6-dihydroxy-4,6-dimethyloxan-2-yl]-8-[4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]-2-[3-(3,3-dimethyloxiran-2-yl)-2-methyloxiran-2-yl]-11-hydroxy-5-methylnaphtho[2,3-h]chromene-4,7,12-trione Chemical compound C1C(N(C)C)C(O)C(C)OC1C1=CC(C2OC(C)(O)C(O)C(C)(C2)N(C)C)=C(O)C2=C1C(=O)C(C=C(C)C=1C(C=C(OC3=1)C1(C)C(O1)C1C(O1)(C)C)=O)=C3C2=O SCWWNJYIUMBQKK-UHFFFAOYSA-N 0.000 title abstract 2
- VNZXPSFYMLCKIO-UHFFFAOYSA-N 10-[3-(dimethylamino)-4,6-dihydroxy-3,6-dimethyloxan-2-yl]-8-[4-(dimethylamino)-3-hydroxy-2-methyl-3,4-dihydro-2h-pyran-6-yl]-2-[3-(3,3-dimethyloxiran-2-yl)-2-methyloxiran-2-yl]-11-hydroxy-5-methylnaphtho[2,3-h]chromene-4,7,12-trione Chemical compound CN(C)C1C(O)C(C)OC(C=2C=3C(=O)C4=C(C5=C(C(C=C(O5)C5(C)C(O5)C5C(O5)(C)C)=O)C(C)=C4)C(=O)C=3C(O)=C(C3C(C(O)CC(C)(O)O3)(C)N(C)C)C=2)=C1 VNZXPSFYMLCKIO-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 2
- 229940088710 antibiotic agent Drugs 0.000 abstract 2
- FXAAZACNORIIQX-UHFFFAOYSA-N 12bh-naphtho[2,3-h]chromene Chemical compound C1=CC=C2C=C(C3OC=CC=C3C=C3)C3=CC2=C1 FXAAZACNORIIQX-UHFFFAOYSA-N 0.000 abstract 1
- 241000187362 Actinomadura Species 0.000 abstract 1
- 241000187361 Actinomadura sp. Species 0.000 abstract 1
- AZGNTCXZZGTRLQ-UHFFFAOYSA-N Antibiotic DC 92D Natural products CN(C)C1C(O)C(C)OC(C=2C=3C(=O)C4=C(C5=C(C(C=C(O5)C5(C)C(O5)C5C(O5)(C)C)=O)C(C)=C4)C(=O)C=3C(O)=C(C3OC(C)(O)C(O)C(C)(C3)N(C)C)C=2)=C1 AZGNTCXZZGTRLQ-UHFFFAOYSA-N 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 229940093499 ethyl acetate Drugs 0.000 abstract 1
- 235000019439 ethyl acetate Nutrition 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000003595 spectral effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17140386 | 1986-07-21 | ||
PCT/JP1987/000524 WO1988000591A1 (en) | 1986-07-21 | 1987-07-17 | Novel substances dc-92b and dc-92d, and process for their preparation |
EP87904737A EP0274545B1 (en) | 1986-07-21 | 1987-07-17 | Novel substances dc-92b and dc-92d, and process for their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE82982T1 true ATE82982T1 (de) | 1992-12-15 |
Family
ID=15922504
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT87904737T ATE82982T1 (de) | 1986-07-21 | 1987-07-17 | Neue mittel dc-92b und dc-92d, sowie deren verfahren zur herstellung. |
Country Status (6)
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01193265A (ja) * | 1988-01-28 | 1989-08-03 | Meiji Seika Kaisha Ltd | 新規抗腫瘍性抗生物質sf2587物質及びその製造法 |
JP2766351B2 (ja) * | 1989-11-13 | 1998-06-18 | 協和醗酵工業株式会社 | 新規物質dc114―c |
US5178896A (en) * | 1991-06-28 | 1993-01-12 | Langner Bruce J | Fiber beverage and method of manufacture |
US5254357A (en) * | 1991-06-28 | 1993-10-19 | Langner Bruce J | Process for making a fiber beverage |
EP1125944A1 (de) * | 2000-02-18 | 2001-08-22 | Aventis Pharma Deutschland GmbH | Pluraflavine und Derivate davon, Verfahren zu ihrer Herstellung und Verwendung derselben |
KR101911767B1 (ko) * | 2017-08-10 | 2018-10-25 | 가톨릭대학교 산학협력단 | 키다마이신 유도체 l1-95-1 및 이를 유효성분으로 함유하는 암 예방 또는 치료용 조성물 |
CN115650913B (zh) * | 2022-10-12 | 2024-03-01 | 北京中医药大学 | 醌式喹啉类化合物及其制备方法和用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3334016A (en) * | 1966-10-24 | 1967-08-01 | Bristol Myers Co | Hedamycin and process for its production |
JPS61274693A (ja) * | 1985-05-29 | 1986-12-04 | Ss Pharmaceut Co Ltd | 新規抗生物質ss21020cおよびその製造法 |
-
1987
- 1987-07-17 JP JP62504380A patent/JPH0819148B1/ja active Pending
- 1987-07-17 WO PCT/JP1987/000524 patent/WO1988000591A1/ja active IP Right Grant
- 1987-07-17 AT AT87904737T patent/ATE82982T1/de active
- 1987-07-17 EP EP87904737A patent/EP0274545B1/en not_active Expired
- 1987-07-17 DE DE8787904737T patent/DE3782930T2/de not_active Expired - Fee Related
- 1987-07-17 US US07/199,043 patent/US4847387A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH0819148B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1996-02-28 |
EP0274545B1 (en) | 1992-12-02 |
WO1988000591A1 (en) | 1988-01-28 |
DE3782930D1 (de) | 1993-01-14 |
EP0274545A4 (en) | 1991-04-17 |
US4847387A (en) | 1989-07-11 |
DE3782930T2 (de) | 1993-04-29 |
EP0274545A1 (en) | 1988-07-20 |
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