ATE82505T1 - Absorptionsverbesserer. - Google Patents

Absorptionsverbesserer.

Info

Publication number
ATE82505T1
ATE82505T1 AT85903967T AT85903967T ATE82505T1 AT E82505 T1 ATE82505 T1 AT E82505T1 AT 85903967 T AT85903967 T AT 85903967T AT 85903967 T AT85903967 T AT 85903967T AT E82505 T1 ATE82505 T1 AT E82505T1
Authority
AT
Austria
Prior art keywords
absorption
scavenger
free radicals
oxygen free
absorption enhancer
Prior art date
Application number
AT85903967T
Other languages
English (en)
Inventor
Stanley Jay Sarnoff
Original Assignee
Survival Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/638,695 external-priority patent/US4658830A/en
Priority claimed from US06/708,845 external-priority patent/US4661469A/en
Priority claimed from US06/735,734 external-priority patent/US4656034A/en
Application filed by Survival Technology filed Critical Survival Technology
Application granted granted Critical
Publication of ATE82505T1 publication Critical patent/ATE82505T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/02—Ammonia; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/446—Superoxide dismutase (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y115/00—Oxidoreductases acting on superoxide as acceptor (1.15)
    • C12Y115/01—Oxidoreductases acting on superoxide as acceptor (1.15) with NAD or NADP as acceptor (1.15.1)
    • C12Y115/01001—Superoxide dismutase (1.15.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT85903967T 1984-08-08 1985-08-08 Absorptionsverbesserer. ATE82505T1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US06/638,695 US4658830A (en) 1984-08-08 1984-08-08 Method and apparatus for initiating reperfusion treatment by an unattended individual undergoing heart attack symptoms
US06/708,845 US4661469A (en) 1984-08-08 1985-03-06 t-PA composition capable of being absorbed into the blood stream and method of administration
US71670585A 1985-03-27 1985-03-27
US06/735,734 US4656034A (en) 1985-05-20 1985-05-20 Absorption enhancing agents
PCT/US1985/001505 WO1986001110A1 (en) 1984-08-08 1985-08-08 Absorption enhancing agents
EP85903967A EP0192660B1 (de) 1984-08-08 1985-08-08 Absorptionsverbesserer

Publications (1)

Publication Number Publication Date
ATE82505T1 true ATE82505T1 (de) 1992-12-15

Family

ID=27505227

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85903967T ATE82505T1 (de) 1984-08-08 1985-08-08 Absorptionsverbesserer.

Country Status (7)

Country Link
EP (1) EP0192660B1 (de)
AT (1) ATE82505T1 (de)
AU (1) AU4674385A (de)
CA (1) CA1265052A (de)
DE (1) DE3586845T2 (de)
IL (1) IL76122A0 (de)
WO (1) WO1986001110A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU598239B2 (en) * 1986-03-13 1990-06-21 Wellcome Foundation Limited, The The application of tissue plasminogen activator and oxypurinol in dissolving blood clots and in preventing damage to ischaemic tissue during reperfusion
CA1284951C (en) * 1986-03-13 1991-06-18 Thomas Spector Cell protection with oxypurinol
WO1988005044A1 (en) * 1986-12-29 1988-07-14 Pharmacia Ab Nitroxide compounds for the preparation of a pharmaceutical composition intended for the prophylaxis and treatment of ischemic cell damage
HU222501B1 (hu) * 1991-06-28 2003-07-28 Endorecherche Inc. MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
US5424471A (en) * 1992-07-31 1995-06-13 U.S. Bioscience, Inc. Crystalline amifostine compositions and methods of the preparation and use of same
SG47101A1 (en) * 1992-07-31 1998-03-20 Us Bioscience Crystalline amifostine compositions and methods for the preparation and use of same
US5912261A (en) * 1994-12-20 1999-06-15 Nippon Zoki Pharmaceutical Co., Ltd. Carboxyalkyl heterocyclic derivatives
US6197806B1 (en) 1995-12-20 2001-03-06 Nippon Zoki Pharmaceutical Co., Ltd. Eliminating agent for activated oxygen and free radicals
JPH10182460A (ja) * 1996-12-27 1998-07-07 Nippon Zoki Pharmaceut Co Ltd ３−デオキシグルコソン生成阻害剤
AU754989B2 (en) 1998-11-16 2002-11-28 Nippon Zoki Pharmaceutical Co., Ltd. A therapeutic agent for intractable vasculitis
JP4711523B2 (ja) 2001-02-13 2011-06-29 日本臓器製薬株式会社 低アルブミン血症改善剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3629410A (en) * 1969-05-23 1971-12-21 Us Army Alpha adrenergic blocking agents
US4346709A (en) * 1980-11-10 1982-08-31 Alza Corporation Drug delivery devices comprising erodible polymer and erosion rate modifier
US4292311A (en) * 1980-12-23 1981-09-29 Sarnoff Stanley J Cyanide antidote

Also Published As

Publication number Publication date
DE3586845D1 (de) 1992-12-24
WO1986001110A1 (en) 1986-02-27
DE3586845T2 (de) 1993-04-01
EP0192660B1 (de) 1992-11-19
EP0192660A1 (de) 1986-09-03
AU4674385A (en) 1986-03-07
IL76122A0 (en) 1985-12-31
CA1265052A (en) 1990-01-30
EP0192660A4 (en) 1990-10-10

Similar Documents

Publication Publication Date Title
ATE82505T1 (de) Absorptionsverbesserer.
ES422884A1 (es) Procedimiento para retardar la descomposicion del peroxido de hidrogeno inducida por el hierro.
DK0495776T3 (da) Stabiliserende nitrogenoxid/primær amin-komplekser, der er anvendelige som cardiovaskulære midler
KR940005633A (ko) 약제학적으로 유용한 항경련제 설파메이트의 이미데이트 유도체
OA09334A (fr) "Dérivés d'acides aminés".
DK358384D0 (da) Farmaceutiske midler til bekaempelse af diabetes mellitus
DK0694545T3 (da) Substituerede dibenzoxazepinforbindelser, farmaceutiske sammensætninger og anvendelsesmetoder
ES8506592A1 (es) Un procedimiento para preparar derivados o-fosforilados de 3-(3,4-dihidroxifenil)alanina (dopa)
SE7709913L (sv) Sett att framstella penta peptider
ES458176A1 (es) Procedimiento para la preparacion de derivados de indazolil-(4)-oxi-propanolamina.
ES447882A1 (es) Procedimiento para la preparacion de agentes bactericidas y fungicidas.
JPS5215549A (en) Stabilized polyurethane compositions
EA200001107A1 (ru) ПРОИЗВОДНЫЕ ОКТАГИДРО-6,10-ДИОКСО-6H-ПИРИДАЗИНО [1,2-a] [1,2] ДИАЗЕПИН-1-КАРБОНОВОЙ КИСЛОТЫ, СПОСОБ ПОЛУЧЕНИЯ И ИХ ПРИМЕНЕНИЕ ДЛЯ ПОЛУЧЕНИЯ ТЕРАПЕВТИЧЕСКИ АКТИВНЫХ СОЕДИНЕНИЙ
EA200000681A1 (ru) Фунгицидная смесь на базе амидных соединений и производных пиридина
GB1020300A (en) Phosphinyl and phosphinothioyl imides, preparation thereof, and compositions
JPS5662835A (en) Stabilization of polyolefin against photodeterioration
ES435422A1 (es) Procedimiento para preparar composiciones fungicidas.
GB1292094A (en) A phenylglycine derivative
ES337700A1 (es) Procedimiento para preparar agentes molusquicidas.
JPS5662839A (en) Treatment for improving weathering resistance of polyolefin
JPS5249260A (en) Stabilized halogen-containing resin compositions
JPS5662837A (en) Stabilization treatment of polyolefin against photodeterioration
JPS5215550A (en) Stabilized polyurethane compositions
JPS5662838A (en) Method for improving weathering resistance of polyolefin
ES410034A1 (es) Procedimiento para la preparacion de 2-(tienil-3'-amino)-1,3 - diazaciclopentenos-(2).

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties