ATE80306T1 - Mittel zur absorptionsverbesserung von proteinen. - Google Patents

Mittel zur absorptionsverbesserung von proteinen.

Info

Publication number
ATE80306T1
ATE80306T1 AT86902132T AT86902132T ATE80306T1 AT E80306 T1 ATE80306 T1 AT E80306T1 AT 86902132 T AT86902132 T AT 86902132T AT 86902132 T AT86902132 T AT 86902132T AT E80306 T1 ATE80306 T1 AT E80306T1
Authority
AT
Austria
Prior art keywords
proteins
improving absorption
absorption
improving
hydroxylamine
Prior art date
Application number
AT86902132T
Other languages
English (en)
Inventor
Stanley Jay Sarnoff
Burton E Sobel
Original Assignee
Survival Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/708,845 external-priority patent/US4661469A/en
Priority claimed from US06/782,441 external-priority patent/US4772585A/en
Application filed by Survival Technology filed Critical Survival Technology
Application granted granted Critical
Publication of ATE80306T1 publication Critical patent/ATE80306T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT86902132T 1985-03-06 1986-03-06 Mittel zur absorptionsverbesserung von proteinen. ATE80306T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US06/708,845 US4661469A (en) 1984-08-08 1985-03-06 t-PA composition capable of being absorbed into the blood stream and method of administration
US71670585A 1985-03-27 1985-03-27
US06/782,441 US4772585A (en) 1984-08-08 1985-10-01 Protein thrombolytic agent with absorption enhancing agent
PCT/US1986/000475 WO1986005096A1 (en) 1985-03-06 1986-03-06 Protein absorption enhancing agents
EP86902132A EP0214281B1 (de) 1985-03-06 1986-03-06 Mittel zur absorptionsverbesserung von proteinen

Publications (1)

Publication Number Publication Date
ATE80306T1 true ATE80306T1 (de) 1992-09-15

Family

ID=27418848

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86902132T ATE80306T1 (de) 1985-03-06 1986-03-06 Mittel zur absorptionsverbesserung von proteinen.

Country Status (9)

Country Link
EP (1) EP0214281B1 (de)
AT (1) ATE80306T1 (de)
AU (1) AU593794B2 (de)
DE (1) DE3686684T2 (de)
DK (1) DK528386A (de)
FI (1) FI864480L (de)
HU (1) HUT41632A (de)
NO (1) NO864382D0 (de)
WO (1) WO1986005096A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4839170A (en) * 1985-10-01 1989-06-13 Survival Technology, Inc. Protein absorption enhancing agents
DE3544663A1 (de) * 1985-12-13 1987-06-19 Schering Ag Thrombosebehandlung mit fibrinolytika und prostacyclinen
DE3729863A1 (de) * 1987-09-05 1989-03-16 Boehringer Mannheim Gmbh Stabilisierte erythropoietin-lyophilisate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU596356B2 (en) * 1985-04-22 1990-05-03 Genentech Inc. Novel human tissue plasminogen activator mutants
NO171344C (no) * 1985-05-28 1993-03-03 Wellcome Found Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator

Also Published As

Publication number Publication date
NO864382L (no) 1986-03-11
DE3686684D1 (de) 1992-10-15
EP0214281A4 (de) 1989-03-16
DE3686684T2 (de) 1993-01-28
NO864382D0 (no) 1986-11-03
AU593794B2 (en) 1990-02-22
AU5581186A (en) 1986-09-24
WO1986005096A1 (en) 1986-09-12
DK528386D0 (da) 1986-11-05
HUT41632A (en) 1987-05-28
EP0214281B1 (de) 1992-09-09
FI864480A7 (fi) 1986-11-04
FI864480A0 (fi) 1986-11-04
EP0214281A1 (de) 1987-03-18
FI864480L (fi) 1986-11-04
DK528386A (da) 1986-11-05

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties