ATE79755T1 - N-(2-carboxy)-ethyl-1,8-naphthalenimid und dessen salze zur behandlung von diabetischen retinopathien und neuropathien. - Google Patents

N-(2-carboxy)-ethyl-1,8-naphthalenimid und dessen salze zur behandlung von diabetischen retinopathien und neuropathien.

Info

Publication number
ATE79755T1
ATE79755T1 AT86108615T AT86108615T ATE79755T1 AT E79755 T1 ATE79755 T1 AT E79755T1 AT 86108615 T AT86108615 T AT 86108615T AT 86108615 T AT86108615 T AT 86108615T AT E79755 T1 ATE79755 T1 AT E79755T1
Authority
AT
Austria
Prior art keywords
carboxy
ethyl
salts
naphthalenimide
neuropathies
Prior art date
Application number
AT86108615T
Other languages
English (en)
Inventor
Paolo Malizia
Original Assignee
I P A International Pharmaceut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by I P A International Pharmaceut filed Critical I P A International Pharmaceut
Application granted granted Critical
Publication of ATE79755T1 publication Critical patent/ATE79755T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT86108615T 1985-06-27 1986-06-24 N-(2-carboxy)-ethyl-1,8-naphthalenimid und dessen salze zur behandlung von diabetischen retinopathien und neuropathien. ATE79755T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8521322A IT1214618B (it) 1985-06-27 1985-06-27 Composti e composizioni farmaceutiche per la terapia di retinopatie e neuropatie diabetiche.
EP86108615A EP0206322B1 (de) 1985-06-27 1986-06-24 N-(2-Carboxy)-ethyl-1,8-naphthalenimid und dessen Salze zur Behandlung von diabetischen Retinopathien und Neuropathien

Publications (1)

Publication Number Publication Date
ATE79755T1 true ATE79755T1 (de) 1992-09-15

Family

ID=11180088

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86108615T ATE79755T1 (de) 1985-06-27 1986-06-24 N-(2-carboxy)-ethyl-1,8-naphthalenimid und dessen salze zur behandlung von diabetischen retinopathien und neuropathien.

Country Status (4)

Country Link
EP (1) EP0206322B1 (de)
AT (1) ATE79755T1 (de)
DE (1) DE3686514T2 (de)
IT (1) IT1214618B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19505941A1 (de) * 1995-02-21 1996-08-22 Bayer Ag 1,8-Naphthalimid-Derivate, Verfahren zur Herstellung und ihre Verwendung als Zwischenprodukte
DE19505942A1 (de) 1995-02-21 1996-08-22 Bayer Ag (Co)Polymerisate auf Basis von Vinyl-Einheiten und ihre Verwendung in elektrolumineszierenden Anordnungen
DE19511484A1 (de) * 1995-03-29 1996-10-02 Bayer Ag (Co)Polymerisate auf Basis von Vinyl-Einheiten und ihre Verwendung in elektrolumineszierenden Anordnungen
US6075106A (en) * 1995-03-29 2000-06-13 D-51368 Bayer Ag (Co)polymers based on vinyl units and use thereof in electroluminescent devices
DE19536843A1 (de) * 1995-10-02 1997-04-03 Bayer Ag (Co)Polymerisate auf Basis von Vinyl-Einheiten und ihre Verwendung in elektrolumineszierenden Anordnungen
DE19632949A1 (de) * 1996-08-16 1998-02-19 Bayer Ag (Co)Polymerisate auf Basis von Vinyl-Einheiten und ihre Verwendung in elektrolumineszierenden Anordnungen
WO1998017278A1 (en) 1996-10-21 1998-04-30 Allelix Biopharmaceuticals Inc. Neurotrophin antagonist compositions
US6015458A (en) * 1998-12-15 2000-01-18 Bayer Corporation Process for the preparation of highly chromatic perylene pigments
US6492380B1 (en) 1999-05-17 2002-12-10 Queen's University At Kingston Method of inhibiting neurotrophin-receptor binding
US6468990B1 (en) * 1999-05-17 2002-10-22 Queen's University At Kingston Method of inhibiting binding of nerve growth factor to p75 NTR receptor
BRPI0615930A2 (pt) 2005-09-15 2016-08-23 Painceptor Pharma Corp métodos de modular a interação de uma neurotrofina e um receptor de neurotrofina, de tratar dor em um indivíduo, de tratar distúrbio inflamatório em um indivíduo, de tratar um distúrbio neurológico em um indivíduo, e de tratar uma doença ou distúrbio associado aos sistemas geniturinário e/ou gastrointestinal de um indivíduo, e, composto

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
US4405625A (en) * 1977-07-25 1983-09-20 Ayerst, Mckenna And Harrison Limited Method of treating hyperglycemia with 1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-acetic acid
RU2051677C1 (ru) * 1982-02-10 1996-01-10 Украинский научно-исследовательский институт эндокринологии и обмена веществ Средство для профилактики и лечения диабетических осложнений, ангиопатий, нейропатий, катаракты

Also Published As

Publication number Publication date
DE3686514D1 (de) 1992-10-01
DE3686514T2 (de) 1993-02-11
EP0206322B1 (de) 1992-08-26
IT8521322A0 (it) 1985-06-27
EP0206322A3 (en) 1990-03-07
IT1214618B (it) 1990-01-18
EP0206322A2 (de) 1986-12-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee