ATE78164T1 - Verwendung von metalloporphyrin zur umkehr des toxischen effekts der tumortherapie. - Google Patents

Verwendung von metalloporphyrin zur umkehr des toxischen effekts der tumortherapie.

Info

Publication number
ATE78164T1
ATE78164T1 AT88908817T AT88908817T ATE78164T1 AT E78164 T1 ATE78164 T1 AT E78164T1 AT 88908817 T AT88908817 T AT 88908817T AT 88908817 T AT88908817 T AT 88908817T AT E78164 T1 ATE78164 T1 AT E78164T1
Authority
AT
Austria
Prior art keywords
metalloporphyrin
reverse
tumor therapy
toxic effect
therapy
Prior art date
Application number
AT88908817T
Other languages
English (en)
Inventor
Attallah Kappas
George S Drummond
Paul S Wissel
Original Assignee
Univ Rockefeller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rockefeller filed Critical Univ Rockefeller
Application granted granted Critical
Publication of ATE78164T1 publication Critical patent/ATE78164T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT88908817T 1987-09-08 1988-09-06 Verwendung von metalloporphyrin zur umkehr des toxischen effekts der tumortherapie. ATE78164T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9381787A 1987-09-08 1987-09-08
PCT/US1988/003052 WO1989002269A1 (en) 1987-09-08 1988-09-06 Use of metalloporphyrins to reverse the toxic effect of tumor therapy
EP88908817A EP0333831B1 (de) 1987-09-08 1988-09-06 Verwendung von metalloporphyrin zur umkehr des toxischen effekts der tumortherapie

Publications (1)

Publication Number Publication Date
ATE78164T1 true ATE78164T1 (de) 1992-08-15

Family

ID=22240903

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88908817T ATE78164T1 (de) 1987-09-08 1988-09-06 Verwendung von metalloporphyrin zur umkehr des toxischen effekts der tumortherapie.

Country Status (10)

Country Link
EP (1) EP0333831B1 (de)
JP (1) JPH02501740A (de)
KR (1) KR890701108A (de)
AT (1) ATE78164T1 (de)
AU (1) AU603938B2 (de)
DE (1) DE3872871T2 (de)
DK (1) DK225689D0 (de)
ES (1) ES2012547A6 (de)
GR (1) GR1000117B (de)
WO (1) WO1989002269A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995031197A1 (en) * 1994-05-13 1995-11-23 Monsanto Company Methods of use for peroxynitrite decomposition catalysts, pharmaceutical compositions therefor
US6245758B1 (en) 1994-05-13 2001-06-12 Michael K. Stern Methods of use for peroxynitrite decomposition catalysts, pharmaceutical compositions therefor
GB9606293D0 (en) * 1996-03-26 1996-05-29 William Harvey Research Limite Treatment of cancers and other tumours
HK1040993B (en) 1999-04-30 2006-11-10 Cellgate, Inc. Polyamines and their use in therapy
US7375216B2 (en) 2002-06-04 2008-05-20 Infacare Pharmaceutical Corporation Preparation of metal mesoporphyrin compounds
CN101573122B (zh) 2006-10-04 2016-08-03 婴儿护理药品公司 锡泊芬的高纯度大规模制备
PT2691398T (pt) 2011-03-30 2017-01-02 Infacare Pharmaceutical Corp Métodos para sintetizar mesoporfirinas de metal

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4386087A (en) * 1981-07-01 1983-05-31 Research Foundation Of The City University Of New York N-Substituted metalloporphyrins as anti-tumor agents against PS-P-388(P388) leukemia in animals
DE8506853U1 (de) * 1985-03-08 1985-10-10 Neumeier, Robert, 8183 Rottach-Egern Verschlußkopf eines aufblasbaren Luftballons
US4668670A (en) * 1986-06-20 1987-05-26 The Rockefeller University Tin diiododeuteroporphyrin and therapeutic use thereof
US4692439A (en) * 1986-06-20 1987-09-08 The Rockefeller University Therapeutic use of tin diiododeuteroporphyrin
US4782049A (en) * 1986-12-08 1988-11-01 The Rockefeller University Tin protoporphyrin and tin mesoporphyrin in the treatment of psoriasis

Also Published As

Publication number Publication date
DK225689A (da) 1989-05-08
KR890701108A (ko) 1989-12-19
WO1989002269A1 (en) 1989-03-23
AU2525488A (en) 1989-04-17
GR1000117B (el) 1991-06-28
DE3872871T2 (de) 1992-12-03
EP0333831A4 (de) 1990-06-26
JPH02501740A (ja) 1990-06-14
DK225689D0 (da) 1989-05-08
EP0333831B1 (de) 1992-07-15
GR880100589A (en) 1989-06-22
DE3872871D1 (de) 1992-08-20
EP0333831A1 (de) 1989-09-27
ES2012547A6 (es) 1990-04-01
AU603938B2 (en) 1990-11-29

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties