ATE77362T1 - Naphthalenische antipsoriasismittel und ihr herstellungsverfahren. - Google Patents

Naphthalenische antipsoriasismittel und ihr herstellungsverfahren.

Info

Publication number
ATE77362T1
ATE77362T1 AT86306903T AT86306903T ATE77362T1 AT E77362 T1 ATE77362 T1 AT E77362T1 AT 86306903 T AT86306903 T AT 86306903T AT 86306903 T AT86306903 T AT 86306903T AT E77362 T1 ATE77362 T1 AT E77362T1
Authority
AT
Austria
Prior art keywords
optionally substituted
substituted phenyl
alkyl
lower alkyl
naphthalene
Prior art date
Application number
AT86306903T
Other languages
English (en)
Inventor
Murthy Dodballapur Ven Krishna
John M Young
Michael C Venuti
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Application granted granted Critical
Publication of ATE77362T1 publication Critical patent/ATE77362T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/32—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/10—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
    • C07C67/11—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond being mineral ester groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/29—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of oxygen-containing functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/017—Esters of hydroxy compounds having the esterified hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/12—Acetic acid esters
    • C07C69/16—Acetic acid esters of dihydroxylic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/22—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
    • C07C69/28—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with dihydroxylic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/63—Halogen-containing esters of saturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/63—Halogen-containing esters of saturated acids
    • C07C69/635—Halogen-containing esters of saturated acids containing rings in the acid moiety

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Insulating Materials (AREA)
  • Luminescent Compositions (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
AT86306903T 1985-09-09 1986-09-08 Naphthalenische antipsoriasismittel und ihr herstellungsverfahren. ATE77362T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77391285A 1985-09-09 1985-09-09
US06/856,929 US4792556A (en) 1985-09-09 1986-04-28 Naphthalene anti-psoriatic agents
EP86306903A EP0215622B1 (de) 1985-09-09 1986-09-08 Naphthalenische Antipsoriasismittel und ihr Herstellungsverfahren

Publications (1)

Publication Number Publication Date
ATE77362T1 true ATE77362T1 (de) 1992-07-15

Family

ID=27118816

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86306903T ATE77362T1 (de) 1985-09-09 1986-09-08 Naphthalenische antipsoriasismittel und ihr herstellungsverfahren.

Country Status (8)

Country Link
US (1) US4792556A (de)
EP (1) EP0215622B1 (de)
AT (1) ATE77362T1 (de)
AU (1) AU603994B2 (de)
DE (1) DE3685702T2 (de)
DK (1) DK428686A (de)
ES (1) ES2001420A6 (de)
NZ (1) NZ217488A (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089657A (en) * 1987-03-11 1992-02-18 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
JP3042156B2 (ja) * 1992-02-20 2000-05-15 田辺製薬株式会社 ナフタレン誘導体、その製法及びその合成中間体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE463409A (de) 1944-11-01
US3592930A (en) 1968-07-19 1971-07-13 Syntex Corp Moisture-deterioratable topical medicaments,particularly anti-inflammatory steroids,in a substantially non-aqueous fatty alcohol-propylene glycol vehicle
US4017615A (en) 1970-10-29 1977-04-12 Syntex Corporation Propylene carbonate ointment vehicle
US3924004A (en) 1971-11-24 1975-12-02 Syntex Corp Fatty alcohol-propylene carbonate-glycol solvent cream vehicle
US3934013A (en) 1975-02-21 1976-01-20 Syntex (U.S.A.) Inc. Pharmaceutical composition
US4593120A (en) * 1982-10-27 1986-06-03 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
US4466981A (en) * 1982-10-27 1984-08-21 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
EP0150831B1 (de) * 1984-01-27 1988-08-10 Syntex (U.S.A.) Inc. Gegen Psoriasis wirkende Naphthalin-Verbindungen

Also Published As

Publication number Publication date
ES2001420A6 (es) 1988-05-16
US4792556A (en) 1988-12-20
EP0215622A3 (en) 1988-07-06
DE3685702T2 (de) 1993-01-21
EP0215622A2 (de) 1987-03-25
AU603994B2 (en) 1990-12-06
DK428686A (da) 1987-03-10
AU6243586A (en) 1987-03-12
EP0215622B1 (de) 1992-06-17
DK428686D0 (da) 1986-09-08
NZ217488A (en) 1990-07-26
DE3685702D1 (de) 1992-07-23

Similar Documents

Publication Publication Date Title
ZA837983B (en) Naphthalene anti-psoriatic agents
ES8600730A1 (es) Procedimiento para la preparacion de agentes anti-psoriaticos del tipo naftalenico
ES8601089A1 (es) Procedimiento para la preparacion de compuestos antipsoria- ticos naftalenicos
ATE77362T1 (de) Naphthalenische antipsoriasismittel und ihr herstellungsverfahren.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee