ATE72560T1 - Inhibitoren der langsam reagierenden anaphylaktischen substanz. - Google Patents

Inhibitoren der langsam reagierenden anaphylaktischen substanz.

Info

Publication number
ATE72560T1
ATE72560T1 AT85304967T AT85304967T ATE72560T1 AT E72560 T1 ATE72560 T1 AT E72560T1 AT 85304967 T AT85304967 T AT 85304967T AT 85304967 T AT85304967 T AT 85304967T AT E72560 T1 ATE72560 T1 AT E72560T1
Authority
AT
Austria
Prior art keywords
tetrazolyl
alkylene
compositions
hydrogen
methods
Prior art date
Application number
AT85304967T
Other languages
English (en)
Inventor
Anil Kumar Saksena
Jesse Kwok-Keung Wong
Pietro Mangiaracina
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE72560T1 publication Critical patent/ATE72560T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/60—Unsaturated compounds containing ether groups, groups, groups, or groups the non-carboxylic part of the ether being unsaturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/04—Acyclic alcohols with carbon-to-carbon triple bonds
    • C07C33/042—Acyclic alcohols with carbon-to-carbon triple bonds with only one triple bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/515—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/222—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms with only carbon-to-carbon triple bonds as unsaturation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT85304967T 1984-07-18 1985-07-11 Inhibitoren der langsam reagierenden anaphylaktischen substanz. ATE72560T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63214384A 1984-07-18 1984-07-18
EP85304967A EP0169033B1 (de) 1984-07-18 1985-07-11 Inhibitoren der langsam reagierenden anaphylaktischen Substanz

Publications (1)

Publication Number Publication Date
ATE72560T1 true ATE72560T1 (de) 1992-02-15

Family

ID=24534262

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85304967T ATE72560T1 (de) 1984-07-18 1985-07-11 Inhibitoren der langsam reagierenden anaphylaktischen substanz.

Country Status (4)

Country Link
EP (1) EP0169033B1 (de)
JP (1) JPS6144842A (de)
AT (1) ATE72560T1 (de)
DE (1) DE3585377D1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4990526A (en) * 1985-06-18 1991-02-05 Merck Frosst Canada, Inc. Leukotriene antagonists, compositions and methods of use thereof
JPS63255937A (ja) * 1987-04-14 1988-10-24 Sumitomo Electric Ind Ltd チツプ実装装置
EP2262764B1 (de) * 2008-04-01 2014-11-12 The University of North Carolina At Chapel Hill Neuartige n-benzylamid-substituierte derivate von 2-(acylamid-)essigsäure und 2-(acylamid-)propionsäuren: starke neurologische wirkstoffe
US8829033B2 (en) 2009-09-23 2014-09-09 The University Of North Carolina At Chapel Hill N-benzylamide substituted derivatives of 2-(acylamido)acetic acid and 2-(acylamido)propionic acids: potent neurological agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2602816A (en) * 1947-06-18 1952-07-08 Goodrich Co B F Method for preparing sulfur-containing carboxylic acids
US3217004A (en) * 1962-05-01 1965-11-09 Carlisle Chemical Works Tin salts of carboxymercaptals
JPS5330653A (en) * 1976-08-09 1978-03-23 Sankyo Yuki Gosei Kk Stabilization of halogen-containing resins
US4623535A (en) * 1984-01-19 1986-11-18 Smithkline Beckman Corporation Leukotriene antagonists

Also Published As

Publication number Publication date
EP0169033A3 (en) 1987-09-16
JPS6144842A (ja) 1986-03-04
DE3585377D1 (de) 1992-03-26
EP0169033B1 (de) 1992-02-12
EP0169033A2 (de) 1986-01-22

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee