ATE64383T1 - 8-phenylthiotetrahydrochinolin-derivate und ihre salze, ihre herstellung, verwendung als arzneimittel und zusammensetzungen davon. - Google Patents
8-phenylthiotetrahydrochinolin-derivate und ihre salze, ihre herstellung, verwendung als arzneimittel und zusammensetzungen davon.Info
- Publication number
- ATE64383T1 ATE64383T1 AT87401466T AT87401466T ATE64383T1 AT E64383 T1 ATE64383 T1 AT E64383T1 AT 87401466 T AT87401466 T AT 87401466T AT 87401466 T AT87401466 T AT 87401466T AT E64383 T1 ATE64383 T1 AT E64383T1
- Authority
- AT
- Austria
- Prior art keywords
- carbon atoms
- salts
- phenylthiotetrahydrochinoline
- derivatives
- compositions
- Prior art date
Links
- BTGXKUFZUPYEAV-UHFFFAOYSA-N 8-phenylsulfanyl-1,2,3,4-tetrahydroquinoline Chemical class C1CCNC2=C1C=CC=C2SC1=CC=CC=C1 BTGXKUFZUPYEAV-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- -1 -OH Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868615563A GB8615563D0 (en) | 1986-06-25 | 1986-06-25 | Chemical compounds |
| EP87401466A EP0254611B1 (de) | 1986-06-25 | 1987-06-25 | 8-Phenylthiotetrahydrochinolin-Derivate und ihre Salze, ihre Herstellung, Verwendung als Arzneimittel und Zusammensetzungen davon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE64383T1 true ATE64383T1 (de) | 1991-06-15 |
Family
ID=10600106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87401466T ATE64383T1 (de) | 1986-06-25 | 1987-06-25 | 8-phenylthiotetrahydrochinolin-derivate und ihre salze, ihre herstellung, verwendung als arzneimittel und zusammensetzungen davon. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4847268A (de) |
| EP (1) | EP0254611B1 (de) |
| JP (1) | JPS635078A (de) |
| AT (1) | ATE64383T1 (de) |
| CA (1) | CA1296337C (de) |
| DE (1) | DE3770713D1 (de) |
| GB (2) | GB8615563D0 (de) |
| GR (1) | GR3002417T3 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8814459D0 (en) * | 1988-06-17 | 1988-07-20 | Wyeth John & Brother Ltd | Pyridine derivatives |
| WO1999067238A2 (en) | 1998-06-25 | 1999-12-29 | Sepracor, Inc. | Tetrahydroquinoline-indole derivatives antimicrobial agents, their uses and compositions containing them |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3509159A (en) * | 1966-07-05 | 1970-04-28 | David Kealey | Preparation of 8-mercaptoquinolines from thiourea and 8-aminoquinoline |
| GB2069493B (en) * | 1980-02-20 | 1984-02-29 | Wyeth John & Brother Ltd | Pyridine derivatives |
-
1986
- 1986-06-25 GB GB868615563A patent/GB8615563D0/en active Pending
-
1987
- 1987-06-16 US US07/062,883 patent/US4847268A/en not_active Expired - Fee Related
- 1987-06-23 CA CA000540380A patent/CA1296337C/en not_active Expired - Fee Related
- 1987-06-24 GB GB8714805A patent/GB2192000B/en not_active Expired - Lifetime
- 1987-06-25 DE DE8787401466T patent/DE3770713D1/de not_active Expired - Fee Related
- 1987-06-25 AT AT87401466T patent/ATE64383T1/de not_active IP Right Cessation
- 1987-06-25 JP JP62156703A patent/JPS635078A/ja active Pending
- 1987-06-25 EP EP87401466A patent/EP0254611B1/de not_active Expired - Lifetime
-
1991
- 1991-08-02 GR GR90401172T patent/GR3002417T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR3002417T3 (en) | 1992-12-30 |
| EP0254611B1 (de) | 1991-06-12 |
| US4847268A (en) | 1989-07-11 |
| GB8615563D0 (en) | 1986-07-30 |
| GB8714805D0 (en) | 1987-07-29 |
| GB2192000B (en) | 1990-05-16 |
| GB2192000A (en) | 1987-12-31 |
| CA1296337C (en) | 1992-02-25 |
| DE3770713D1 (de) | 1991-07-18 |
| JPS635078A (ja) | 1988-01-11 |
| EP0254611A1 (de) | 1988-01-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |