ATE64302T1 - Isolierung und kultur von faktor viii:c produzierenden adrenalmedullarischen endothelialen zellen. - Google Patents

Isolierung und kultur von faktor viii:c produzierenden adrenalmedullarischen endothelialen zellen.

Info

Publication number
ATE64302T1
ATE64302T1 AT85402222T AT85402222T ATE64302T1 AT E64302 T1 ATE64302 T1 AT E64302T1 AT 85402222 T AT85402222 T AT 85402222T AT 85402222 T AT85402222 T AT 85402222T AT E64302 T1 ATE64302 T1 AT E64302T1
Authority
AT
Austria
Prior art keywords
factor viii
producing
adrenalmedullary
culture
isolation
Prior art date
Application number
AT85402222T
Other languages
English (en)
Inventor
Harvey B Pollard
Richard Ornberg
Dipak Banerjee
Moussa Youdim
Peter Lelkes
Eli Heldman
Original Assignee
Partnership Of Harvey B Pollar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Partnership Of Harvey B Pollar filed Critical Partnership Of Harvey B Pollar
Application granted granted Critical
Publication of ATE64302T1 publication Critical patent/ATE64302T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT85402222T 1984-11-16 1985-11-15 Isolierung und kultur von faktor viii:c produzierenden adrenalmedullarischen endothelialen zellen. ATE64302T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/672,451 US4670394A (en) 1984-11-16 1984-11-16 Isolation and culture of adrenal medullary endothelial cells producing blood clotting factor VIII:C
EP85402222A EP0187556B1 (de) 1984-11-16 1985-11-15 Isolierung und Kultur von Faktor VIII:C produzierenden adrenalmedullarischen endothelialen Zellen

Publications (1)

Publication Number Publication Date
ATE64302T1 true ATE64302T1 (de) 1991-06-15

Family

ID=24698595

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85402222T ATE64302T1 (de) 1984-11-16 1985-11-15 Isolierung und kultur von faktor viii:c produzierenden adrenalmedullarischen endothelialen zellen.

Country Status (8)

Country Link
US (1) US4670394A (de)
EP (1) EP0187556B1 (de)
JP (1) JPS61225128A (de)
AT (1) ATE64302T1 (de)
CA (1) CA1309676C (de)
DE (1) DE3583227D1 (de)
GR (1) GR852771B (de)
IL (1) IL77049A0 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250421A (en) * 1986-01-03 1993-10-05 Genetics Institute, Inc. Method for producing factor VIII:C-type proteins
US5198349A (en) * 1986-01-03 1993-03-30 Genetics Institute, Inc. Method for producing factor VIII:C and analogs
US5176998A (en) * 1986-12-01 1993-01-05 The Scripps Research Institute Cell surface antigen detection method
US4810632A (en) * 1986-12-01 1989-03-07 Scripps Clinic And Research Foundation Cell surface antigen detection method
DK629387D0 (da) * 1987-12-01 1987-12-01 Novo Industri As Fremgangsmaade
GB8728854D0 (en) * 1987-12-10 1988-01-27 British Telecomm Optical device
US6899882B1 (en) * 1989-03-24 2005-05-31 The Regents Of The University Of California Endothelial cell growth factor methods of isolation and expression
FR2657884B1 (fr) * 1990-02-05 1994-09-02 Tm Innovation Procede pour la preparation du facteur viii humain et d'analogues du facteur viii.
FR2670215B1 (fr) * 1990-12-10 2000-10-13 Lignees de cellules immortalisees et leurs applications, notamment a la production de cellules differenciees.
AU2572692A (en) 1991-09-09 1993-04-05 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Methods and devices for treating hemophilia and aids
US5409833A (en) * 1993-07-01 1995-04-25 Baxter International Inc. Microvessel cell isolation apparatus

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE448945B (sv) * 1979-12-20 1987-03-30 Blombaeck E G B Forfarande for rening och /eller koncentrering av faktor viii-komplexet
US4440679A (en) * 1980-03-05 1984-04-03 Cutter Laboratories, Inc. Pasteurized therapeutically active protein compositions
DE3033932C2 (de) * 1980-09-10 1984-05-24 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Kaltsterilisation von Blutgerinnungsfaktor VIII enthaltenden Präparaten
JPS5874617A (ja) * 1981-10-28 1983-05-06 Green Cross Corp:The 人由来血液凝固第７因子含有水溶液の加熱処理方法
US4534972A (en) * 1983-03-29 1985-08-13 Miles Laboratories, Inc. Protein compositions substantially free from infectious agents
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives

Also Published As

Publication number Publication date
EP0187556A3 (en) 1988-04-27
JPS61225128A (ja) 1986-10-06
CA1309676C (en) 1992-11-03
US4670394A (en) 1987-06-02
EP0187556A2 (de) 1986-07-16
DE3583227D1 (de) 1991-07-18
IL77049A0 (en) 1986-04-29
GR852771B (de) 1986-03-19
EP0187556B1 (de) 1991-06-12

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