ATE59968T1 - Transdermale abgabevorrichtung mit gradkontrollierendem klebstoff. - Google Patents

Transdermale abgabevorrichtung mit gradkontrollierendem klebstoff.

Info

Publication number
ATE59968T1
ATE59968T1 AT87307696T AT87307696T ATE59968T1 AT E59968 T1 ATE59968 T1 AT E59968T1 AT 87307696 T AT87307696 T AT 87307696T AT 87307696 T AT87307696 T AT 87307696T AT E59968 T1 ATE59968 T1 AT E59968T1
Authority
AT
Austria
Prior art keywords
transdermal delivery
delivery device
adhesive
level
eva
Prior art date
Application number
AT87307696T
Other languages
English (en)
Inventor
David J Enscore
Eun Soo Lee
Sun Il Yum
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE59968T1 publication Critical patent/ATE59968T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coating Apparatus (AREA)
AT87307696T 1986-09-02 1987-09-01 Transdermale abgabevorrichtung mit gradkontrollierendem klebstoff. ATE59968T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/903,002 US4938759A (en) 1986-09-02 1986-09-02 Transdermal delivery device having a rate controlling adhesive
EP87307696A EP0259136B1 (de) 1986-09-02 1987-09-01 Transdermale Abgabevorrichtung mit Gradkontrollierendem Klebstoff

Publications (1)

Publication Number Publication Date
ATE59968T1 true ATE59968T1 (de) 1991-02-15

Family

ID=25416765

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87307696T ATE59968T1 (de) 1986-09-02 1987-09-01 Transdermale abgabevorrichtung mit gradkontrollierendem klebstoff.

Country Status (8)

Country Link
US (1) US4938759A (de)
EP (1) EP0259136B1 (de)
JP (1) JP2511472B2 (de)
AT (1) ATE59968T1 (de)
CA (1) CA1297754C (de)
DE (1) DE3767412D1 (de)
ES (1) ES2020278B3 (de)
GR (1) GR3001328T3 (de)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725439A (en) * 1984-06-29 1988-02-16 Alza Corporation Transdermal drug delivery device
JPS6468316A (en) * 1987-09-08 1989-03-14 Teikoku Seiyaku Kk External plaster containing salbutamol
JPH0725669B2 (ja) * 1988-12-23 1995-03-22 日東電工株式会社 経皮投与用医薬製剤
US5788983A (en) * 1989-04-03 1998-08-04 Rutgers, The State University Of New Jersey Transdermal controlled delivery of pharmaceuticals at variable dosage rates and processes
NZ237241A (en) * 1990-03-02 1993-11-25 Pharmetrix Corp Method for increasing the storage stability of physostigmine
US5513660A (en) * 1990-12-31 1996-05-07 Uromed Corporation Expandable urethral plug
US5724994A (en) * 1990-12-31 1998-03-10 Uromed Corporation Fluidly expandable urethral plug assembly which receives fluid from an external source and method for controlling urinary incontinence
US5509427A (en) * 1990-12-31 1996-04-23 Uromed Corporation Urethral plug assembly having adhesive for enhanced sealing capabilities and method of using said plug assembly
US5479945A (en) * 1990-12-31 1996-01-02 Uromed Corporation Method and a removable device which can be used for the self-administered treatment of urinary tract infections or other disorders
US5705185A (en) * 1991-09-25 1998-01-06 Beta Pharmaceuticals Co. Transdermal delivery of estradiol and process for manufacturing said device
US5518734A (en) * 1991-09-25 1996-05-21 Beta Pharmaceuticals Co. Transdermal delivery system for estradiol and process for manufacturing said device
US5613958A (en) * 1993-05-12 1997-03-25 Pp Holdings Inc. Transdermal delivery systems for the modulated administration of drugs
US5769091A (en) * 1993-09-20 1998-06-23 Uromed Corporation Urethral plug having adhesive for enhanced sealing capabilities and method of using said plug
ES2172584T3 (es) * 1994-05-18 2002-10-01 Hisamitsu Pharmaceutical Co Preparacion administrable por via percutanea para tratar trastornos de la miccion.
TW592729B (en) * 1995-04-06 2004-06-21 Janssen Pharmaceutica Nv Rate-controlled transdermal administration of risperidone
US5840327A (en) * 1995-08-21 1998-11-24 Alza Corporation Transdermal drug delivery device having enhanced adhesion
US5660431A (en) * 1996-07-09 1997-08-26 Leach; Thomas R. Rocker conversion for lawn-type chairs
US6512010B1 (en) 1996-07-15 2003-01-28 Alza Corporation Formulations for the administration of fluoxetine
US6203817B1 (en) 1997-02-19 2001-03-20 Alza Corporation Reduction of skin reactions caused by transdermal drug delivery
US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
US5965624A (en) * 1997-06-27 1999-10-12 Eval Company Of America Self purging EVOH compositions, and methods
US6660295B2 (en) 1997-09-30 2003-12-09 Alza Corporation Transdermal drug delivery device package with improved drug stability
WO1999064501A1 (en) 1998-06-11 1999-12-16 The Dow Chemical Company Elastic films made from alpha-olefin/vinyl aromatic and/or aliphatic or cylcoaliphatic vinyl or vinylidene interpolymers
US6699497B1 (en) 1998-07-24 2004-03-02 Alza Corporation Formulations for the transdermal administration of fenoldopam
US6348210B1 (en) 1998-11-13 2002-02-19 Alza Corporation Methods for transdermal drug administration
EP2158903A3 (de) 1998-12-18 2010-04-14 ALZA Corporation Transparente transdermale Nikotinabgabevorrichtungen
US20030170195A1 (en) * 2000-01-10 2003-09-11 Noven Pharmaceuticals, Inc. Compositions and methods for drug delivery
ATE288256T1 (de) * 1999-01-14 2005-02-15 Noven Pharma Dermale zusammensetzungen
WO2000059483A2 (en) * 1999-04-01 2000-10-12 Alza Corporation Transdermal drug delivery devices comprising a polyurethane drug reservoir
DE10033853A1 (de) * 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
CA2460352C (en) * 2001-08-17 2013-05-14 Lavipharm Laboratories Inc. Composition and transdermal drug delivery device
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
AR033748A1 (es) * 2002-05-15 2004-01-07 Thalas Group Inc Un dispositivo para la administracion transdermica de sustancias farmacologicamente activas que comprende dos capas adhesivas superpuestas y un procedimiento para prepararlo
US20040086551A1 (en) * 2002-10-30 2004-05-06 Miller Kenneth J. Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl
US20070031463A1 (en) * 2003-02-26 2007-02-08 Spiros Fotinos Methods and devices for releasing volatile substances
US20040258742A1 (en) * 2003-04-11 2004-12-23 Van Osdol William Woodson Transdermal administration of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methyl guanidines
AU2004233997C1 (en) * 2003-04-29 2014-01-30 Massachusetts Institiute Of Technology Methods and devices for the sustained release of multiple drugs
MEP23508A (en) * 2003-10-28 2010-06-10 Noven Pharma Compositions and methods for comtrolling drug loss and delivery in transdermal drug delivery systems
US20050202073A1 (en) 2004-03-09 2005-09-15 Mylan Technologies, Inc. Transdermal systems containing multilayer adhesive matrices to modify drug delivery
US9205062B2 (en) 2004-03-09 2015-12-08 Mylan Pharmaceuticals, Inc. Transdermal systems containing multilayer adhesive matrices to modify drug delivery
US7591806B2 (en) * 2004-05-18 2009-09-22 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
WO2006041911A2 (en) 2004-10-08 2006-04-20 Noven Pharmaceuticals, Inc. Device transdermal administration of drugs including acrylic polymers
US8343538B2 (en) * 2004-10-08 2013-01-01 Noven Pharmaceuticals, Inc. Compositions and methods for controlling the flux of a drug from a transdermal drug delivery systems
US8252320B2 (en) 2004-10-21 2012-08-28 Durect Corporation Transdermal delivery system for sufentanil
US8246977B2 (en) 2004-10-21 2012-08-21 Durect Corporation Transdermal delivery systems
US8043250B2 (en) * 2005-05-18 2011-10-25 Nanomed Devices, Inc. High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US8048017B2 (en) * 2005-05-18 2011-11-01 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US8518926B2 (en) * 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
WO2007121188A2 (en) * 2006-04-10 2007-10-25 Knopp Neurosciences, Inc. Compositions and methods of using r(+) pramipexole
ES2379117T3 (es) 2006-05-16 2012-04-20 Knopp Neurosciences, Inc. Composiciones de R(+) y S(-) pramipexol y métodos de utilización de las mismas
AU2007325918B2 (en) 2006-11-03 2013-10-17 Durect Corporation Transdermal delivery systems comprising bupivacaine
US8524695B2 (en) * 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
US20080214987A1 (en) * 2006-12-22 2008-09-04 Nanomed Devices, Inc. Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances
US10525246B2 (en) 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
CA2681110A1 (en) * 2007-03-14 2008-09-18 Knopp Neurosciences, Inc. Synthesis of chirally purified substituted benzothiazole diamines
US8231906B2 (en) 2008-07-10 2012-07-31 Noven Pharmaceuticals, Inc. Transdermal estrogen device and delivery
KR20110071064A (ko) * 2008-08-19 2011-06-28 크놉 뉴로사이언시스 인코포레이티드 (ｒ)-프라미펙솔을 사용하는 조성물 및 방법
RU2012101792A (ru) * 2009-06-19 2013-07-27 Нопп Ньюросайенсиз, Инк. Композиции и способы для лечения бокового амиотрофического склероза
JP5927506B2 (ja) 2010-04-13 2016-06-01 レルマダ セラピューティクス、インク． １−メチル−２’，６’−ピペコロキシリダイドの皮膚医薬組成物および使用方法
WO2012096866A2 (en) 2011-01-10 2012-07-19 Inverseon, Inc. Use of beta-adrenergic inverse agonists for smoking cessation
WO2013096816A1 (en) 2011-12-22 2013-06-27 Biogen Idec Ma Inc. Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
US9682068B2 (en) 2013-05-20 2017-06-20 Mylan Inc. Transdermal therapeutic system for extended dosing of pramipexole in treating neurological disorders
EP3838271B1 (de) 2013-07-12 2025-09-03 Areteia Therapeutics, Inc. Behandlung eines erhöhten spiegels von eosinophilen und/oder basophilen
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
CA2921381A1 (en) 2013-08-13 2015-02-19 Knopp Biosciences Llc Compositions and methods for treating chronic urticaria
ES2813674T3 (es) 2013-08-13 2021-03-24 Knopp Biosciences Llc Composiciones y métodos para el tratamiento de trastornos de células plasmáticas y trastornos prolinfocíticos de células b
BR112017016325B1 (pt) * 2015-01-30 2023-02-28 Daio Paper Corporation Artigo absorvente e método de fabricação
JP6240733B1 (ja) * 2016-09-30 2017-11-29 大王製紙株式会社 使い捨て着用物品及びその製造方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598122A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US3699963A (en) * 1969-10-31 1972-10-24 Alza Corp Therapeutic adhesive patch
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US3742951A (en) * 1971-08-09 1973-07-03 Alza Corp Bandage for controlled release of vasodilators
US3926188A (en) * 1974-11-14 1975-12-16 Alza Corp Laminated drug dispenser
US4144317A (en) * 1975-05-30 1979-03-13 Alza Corporation Device consisting of copolymer having acetoxy groups for delivering drugs
US4262003A (en) 1975-12-08 1981-04-14 Alza Corporation Method and therapeutic system for administering scopolamine transdermally
US4031894A (en) * 1975-12-08 1977-06-28 Alza Corporation Bandage for transdermally administering scopolamine to prevent nausea
US4060084A (en) * 1976-09-07 1977-11-29 Alza Corporation Method and therapeutic system for providing chemotherapy transdermally
US4286592A (en) * 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
US4314557A (en) * 1980-05-19 1982-02-09 Alza Corporation Dissolution controlled active agent dispenser
US4379454A (en) * 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
US4605548A (en) * 1983-05-31 1986-08-12 Nitto Electric Industrial Co., Ltd. Drug administration material
DE3347278A1 (de) * 1983-12-28 1985-07-11 Bayer Ag, 5090 Leverkusen Wirkstoffabgabesysteme
US4752478A (en) * 1984-12-17 1988-06-21 Merck & Co., Inc. Transdermal system for timolol
US4615699A (en) * 1985-05-03 1986-10-07 Alza Corporation Transdermal delivery system for delivering nitroglycerin at high transdermal fluxes

Also Published As

Publication number Publication date
GR3001328T3 (en) 1992-08-31
EP0259136A3 (en) 1989-03-15
CA1297754C (en) 1992-03-24
US4938759A (en) 1990-07-03
EP0259136B1 (de) 1991-01-16
JP2511472B2 (ja) 1996-06-26
DE3767412D1 (de) 1991-02-21
JPS63119421A (ja) 1988-05-24
ES2020278B3 (es) 1991-08-01
EP0259136A2 (de) 1988-03-09

Similar Documents

Publication Publication Date Title
ATE59968T1 (de) Transdermale abgabevorrichtung mit gradkontrollierendem klebstoff.
EP0279986B1 (de) Glycerolmonolaurate enthaltende, die Hautpermeabilität vergrössernde Zusammensetzungen
ES287385U (es) Esparadrapo autoadhesivo
FI920960A0 (fi) Fast matrissystem foer transdermal dosering av laekemedelsaemnen.
EP0409910A4 (en) Laminated composite for transdermal administration of fentanyl
BE896578A (fr) Dispositif d'administration soutenue d'un medicament.
ES8802276A1 (es) Metodo para la fabricacion de dispositivos de liberacion a velocidad controlada de agentes beneficiosos.
DE3688075D1 (de) Transdermales verabreichungssystem.
ATE103819T1 (de) Pharmazeutische praeparate.
EP0160501A3 (de) Intranasale Zusammenstellung mit verzögerter Freigabe und Gebrauchsanweisung
DE3751761D1 (de) Penetrationsverbesserer für die transdermale Verabreichung von systemisch wirksamen Arzneimitteln
CA2006511A1 (en) Percutaneous preparation of tulobuterol
ATE84714T1 (de) Transkutane verabreichung von pharmazeutika.
ATE146676T1 (de) Transdermales therapeutisches system für broncholytika
ATE84975T1 (de) Pharmazeutische praeparate.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee