ATE547388T1 - Verfahren zur verwendung von ä11cükohlenmonoxid zur markierenden synthese von 11c-markierten estern durch sensibilisierte photoinduzierte radikalische carbonylierung - Google Patents

Verfahren zur verwendung von ä11cükohlenmonoxid zur markierenden synthese von 11c-markierten estern durch sensibilisierte photoinduzierte radikalische carbonylierung

Info

Publication number
ATE547388T1
ATE547388T1 AT06744810T AT06744810T ATE547388T1 AT E547388 T1 ATE547388 T1 AT E547388T1 AT 06744810 T AT06744810 T AT 06744810T AT 06744810 T AT06744810 T AT 06744810T AT E547388 T1 ATE547388 T1 AT E547388T1
Authority
AT
Austria
Prior art keywords
esters
carbon monoxide
labled
labeling synthesis
carbonylation
Prior art date
Application number
AT06744810T
Other languages
English (en)
Inventor
Bengt Langstrom
Oleksiy Itsenko
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Application granted granted Critical
Publication of ATE547388T1 publication Critical patent/ATE547388T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001Acyclic or carbocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/10Preparation of carboxylic acids or their salts, halides or anhydrides by reaction with carbon monoxide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/36Preparation of carboxylic acid esters by reaction with carbon monoxide or formates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/75Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of acids with a six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT06744810T 2005-06-08 2006-06-05 Verfahren zur verwendung von ä11cükohlenmonoxid zur markierenden synthese von 11c-markierten estern durch sensibilisierte photoinduzierte radikalische carbonylierung ATE547388T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68846905P 2005-06-08 2005-06-08
PCT/IB2006/001452 WO2006131803A2 (en) 2005-06-08 2006-06-05 Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled esters and acids by sensitized photo-induced free radical carbonylation

Publications (1)

Publication Number Publication Date
ATE547388T1 true ATE547388T1 (de) 2012-03-15

Family

ID=37103323

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06744810T ATE547388T1 (de) 2005-06-08 2006-06-05 Verfahren zur verwendung von ä11cükohlenmonoxid zur markierenden synthese von 11c-markierten estern durch sensibilisierte photoinduzierte radikalische carbonylierung

Country Status (5)

Country Link
US (2) US20080226555A1 (de)
EP (1) EP1896380B1 (de)
AT (1) ATE547388T1 (de)
ES (1) ES2380680T3 (de)
WO (1) WO2006131803A2 (de)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6437103B1 (en) * 1999-04-14 2002-08-20 Biostream Inc. Fatty acid analogs for diagnosis of coronary artery disease
SE0102174D0 (sv) * 2001-06-19 2001-06-19 Tor Kihlberg Method and apparatus for production and use of (11C) carbon monoxide in labeling synthesis
GB0116815D0 (en) * 2001-07-10 2001-08-29 Nycomed Amersham Plc Improved chelator conjugates
ES2320897T3 (es) * 2003-10-31 2009-05-29 Ge Healthcare Limited Procedimiento y aparato para el uso de monoxido de carbono (11c) en la sintesis de marcaje mediante carbonilacion fotoiniciada.
US7667011B2 (en) * 2004-12-03 2010-02-23 Bengt Langstrom Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled acids by photo-induced free radical carbonylation

Also Published As

Publication number Publication date
ES2380680T3 (es) 2012-05-17
US20080226555A1 (en) 2008-09-18
EP1896380A2 (de) 2008-03-12
WO2006131803A3 (en) 2007-03-01
WO2006131803A2 (en) 2006-12-14
EP1896380B1 (de) 2012-02-29
US20100158804A1 (en) 2010-06-24

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