ATE544070T1 - Verfahren zum nachweis von tumorspezifischen fusionsproteinen - Google Patents
Verfahren zum nachweis von tumorspezifischen fusionsproteinenInfo
- Publication number
- ATE544070T1 ATE544070T1 AT09731266T AT09731266T ATE544070T1 AT E544070 T1 ATE544070 T1 AT E544070T1 AT 09731266 T AT09731266 T AT 09731266T AT 09731266 T AT09731266 T AT 09731266T AT E544070 T1 ATE544070 T1 AT E544070T1
- Authority
- AT
- Austria
- Prior art keywords
- fusion proteins
- specific fusion
- detecting tumor
- detection
- relates
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 102000037865 fusion proteins Human genes 0.000 title 1
- 108020001507 fusion proteins Proteins 0.000 title 1
- 238000001514 detection method Methods 0.000 abstract 2
- 208000031404 Chromosome Aberrations Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 231100000005 chromosome aberration Toxicity 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000012631 diagnostic technique Methods 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57426—Specifically defined cancers leukemia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/82—Translation products from oncogenes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12336908P | 2008-04-07 | 2008-04-07 | |
| EP08154164A EP2108956A1 (de) | 2008-04-07 | 2008-04-07 | Verbesserte Verfahren und Kits zum Erkennen von tumorspezifischen Fusionsproteinen |
| PCT/EP2009/054072 WO2009124901A1 (en) | 2008-04-07 | 2009-04-06 | Methods and kits for detecting tumor-specific fusion proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE544070T1 true ATE544070T1 (de) | 2012-02-15 |
Family
ID=39764992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT09731266T ATE544070T1 (de) | 2008-04-07 | 2009-04-06 | Verfahren zum nachweis von tumorspezifischen fusionsproteinen |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20110027808A1 (de) |
| EP (2) | EP2108956A1 (de) |
| JP (1) | JP2011519022A (de) |
| AT (1) | ATE544070T1 (de) |
| WO (1) | WO2009124901A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2558797C2 (ru) * | 2009-10-20 | 2015-08-10 | Нестек С.А. | Способы выявления онкогенных слитых белков, основанные на анализе близкого взаимного расположения |
| CN101955991B (zh) * | 2010-03-31 | 2014-05-28 | 江苏迈迪基因生物科技有限公司 | 白血病相关的融合基因的联合检测方法及诊断试剂盒 |
| DE102010031923A1 (de) | 2010-07-22 | 2012-01-26 | Giesecke & Devrient Gmbh | Sicherheitsfaden für Datenträger sowie Datenträger und deren Herstellung |
| WO2012140209A1 (en) * | 2011-04-15 | 2012-10-18 | Vivabiocell S.P.A. | Immunodiagnostic method for diagnosing auto-immune systemic sclerosis (ssc) and systemic lupus erythematosus (sle) |
| KR101439856B1 (ko) * | 2011-06-02 | 2014-09-17 | 한국생명공학연구원 | 항-ａｔｉｃ 자가면역항체를 포함하는 간암 진단 마커 및 이의 항원을 포함하는 간암 진단용 조성물 |
| US20160010068A1 (en) * | 2013-02-22 | 2016-01-14 | Boris C. Bastian | Fusion polynucleotides and fusion polypeptides associated with cancer and particularly melanoma and their uses as therapeutic and diagnostic targets |
| EP3554557A4 (de) | 2016-12-13 | 2020-07-29 | University of Pittsburgh - of The Commonwealth System of Higher Education | Verfahren zur behandlung von zellen, die fusionsgene enthalten, durch genomisches targeting |
| JP7042045B2 (ja) * | 2017-08-10 | 2022-03-25 | シスメックス株式会社 | 試料分析装置 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL78703A (en) | 1985-05-10 | 1993-02-21 | Benzon Alfred | Method of producing extracellular enzymes, the enzymes produced thereby and compositions containing them; a hybrid plasmid and a dna fragment comprising dna encoding the enzymes; a microorganism harbouring the plasmid; and a method for removing nucleic acids from biological materials |
| US5173418A (en) | 1985-05-10 | 1992-12-22 | Benzon Pharma, A/S | Production in Escherichia coli of extracellular Serratia spp. hydrolases |
| US6686165B2 (en) | 1997-05-20 | 2004-02-03 | Erasmus Universiteit Rotterdam | Recognition of tumor-specific gene products in cancer |
| WO2000050903A1 (en) | 1999-02-24 | 2000-08-31 | Luminex Corporation | Particulate solid phase immobilized protein quantitation |
| DK1534848T3 (da) | 2002-09-02 | 2008-01-07 | Merck Patent Gmbh | Fremgangsmåde til ekstraktion af proteiner |
| CA2529053A1 (en) * | 2003-06-18 | 2004-12-29 | Onyx Pharmaceuticals, Inc. | Method for purifying virus |
| EP1507147A1 (de) * | 2003-08-12 | 2005-02-16 | Erasmus University Medical Center Rotterdam | Verfahren zum Nachweiss von niedrigem Gehalt an Fusionsprotein |
| US20070015134A1 (en) | 2005-07-15 | 2007-01-18 | Beckman Coulter, Inc. | Quantitative stabilized cell reference control products and methods |
| WO2007061684A1 (en) * | 2005-11-18 | 2007-05-31 | Board Of Regents, The University Of Texas System | Quantification of fusion proteins and their activity from chromosomal translocation |
-
2008
- 2008-04-07 EP EP08154164A patent/EP2108956A1/de not_active Ceased
-
2009
- 2009-04-06 WO PCT/EP2009/054072 patent/WO2009124901A1/en active Application Filing
- 2009-04-06 US US12/736,411 patent/US20110027808A1/en not_active Abandoned
- 2009-04-06 JP JP2011503410A patent/JP2011519022A/ja active Pending
- 2009-04-06 AT AT09731266T patent/ATE544070T1/de active
- 2009-04-06 EP EP09731266A patent/EP2260304B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| EP2260304A1 (de) | 2010-12-15 |
| JP2011519022A (ja) | 2011-06-30 |
| EP2108956A1 (de) | 2009-10-14 |
| EP2260304B1 (de) | 2012-02-01 |
| US20110027808A1 (en) | 2011-02-03 |
| WO2009124901A8 (en) | 2011-04-14 |
| WO2009124901A1 (en) | 2009-10-15 |
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