ATE543504T1 - Hox peptide als pbx-modulatoren zur behandlung von krebs - Google Patents
Hox peptide als pbx-modulatoren zur behandlung von krebsInfo
- Publication number
- ATE543504T1 ATE543504T1 AT06755670T AT06755670T ATE543504T1 AT E543504 T1 ATE543504 T1 AT E543504T1 AT 06755670 T AT06755670 T AT 06755670T AT 06755670 T AT06755670 T AT 06755670T AT E543504 T1 ATE543504 T1 AT E543504T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acid
- absent
- side chain
- sequence
- amino acids
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 235000001014 amino acid Nutrition 0.000 abstract 17
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 12
- 150000001413 amino acids Chemical class 0.000 abstract 9
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 230000002209 hydrophobic effect Effects 0.000 abstract 2
- 125000001433 C-terminal amino-acid group Chemical group 0.000 abstract 1
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 abstract 1
- 230000001594 aberrant effect Effects 0.000 abstract 1
- 229920006317 cationic polymer Polymers 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000032823 cell division Effects 0.000 abstract 1
- 235000018417 cysteine Nutrition 0.000 abstract 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69513605P | 2005-06-29 | 2005-06-29 | |
| PCT/GB2006/002390 WO2007000601A2 (en) | 2005-06-29 | 2006-06-28 | Gene regulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE543504T1 true ATE543504T1 (de) | 2012-02-15 |
Family
ID=37595498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06755670T ATE543504T1 (de) | 2005-06-29 | 2006-06-28 | Hox peptide als pbx-modulatoren zur behandlung von krebs |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090286738A1 (https=) |
| EP (1) | EP1909811B1 (https=) |
| JP (1) | JP2009500314A (https=) |
| AT (1) | ATE543504T1 (https=) |
| WO (1) | WO2007000601A2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012513218A (ja) * | 2008-12-23 | 2012-06-14 | ヴィヴォスクリプト，インコーポレイテッド | 遺伝子改変を伴わずに細胞を再プログラミングするための組成物および方法 |
| GB2543550A (en) * | 2015-10-21 | 2017-04-26 | Hox Therapeutics Ltd | Peptides |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997042222A1 (en) * | 1996-05-08 | 1997-11-13 | Cyclacel Limited | Methods and means for inhibition of cdk4 activity |
| US20020086383A1 (en) * | 2000-02-23 | 2002-07-04 | Guy Sauvageau | Hematopoietic stem cell expansion enhancing factor and method of use |
| GB0229151D0 (en) * | 2002-12-13 | 2003-01-15 | St Georges Entpr Ltd | Product and method |
-
2006
- 2006-06-28 WO PCT/GB2006/002390 patent/WO2007000601A2/en not_active Ceased
- 2006-06-28 EP EP06755670A patent/EP1909811B1/en not_active Not-in-force
- 2006-06-28 AT AT06755670T patent/ATE543504T1/de active
- 2006-06-28 US US11/993,978 patent/US20090286738A1/en not_active Abandoned
- 2006-06-28 JP JP2008518963A patent/JP2009500314A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1909811B1 (en) | 2012-02-01 |
| WO2007000601A2 (en) | 2007-01-04 |
| EP1909811A2 (en) | 2008-04-16 |
| WO2007000601A8 (en) | 2008-03-27 |
| JP2009500314A (ja) | 2009-01-08 |
| WO2007000601A3 (en) | 2007-05-18 |
| US20090286738A1 (en) | 2009-11-19 |
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