ATE539160T1 - Verfahren zur erhöhung der produktion von proteinen - Google Patents
Verfahren zur erhöhung der produktion von proteinenInfo
- Publication number
- ATE539160T1 ATE539160T1 AT98102626T AT98102626T ATE539160T1 AT E539160 T1 ATE539160 T1 AT E539160T1 AT 98102626 T AT98102626 T AT 98102626T AT 98102626 T AT98102626 T AT 98102626T AT E539160 T1 ATE539160 T1 AT E539160T1
- Authority
- AT
- Austria
- Prior art keywords
- proteins
- promoter
- increase production
- coding sequence
- sequence
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/807,415 US5854021A (en) | 1997-02-28 | 1997-02-28 | Enhance protein production method |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE539160T1 true ATE539160T1 (de) | 2012-01-15 |
Family
ID=25196326
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98102626T ATE539160T1 (de) | 1997-02-28 | 1998-02-16 | Verfahren zur erhöhung der produktion von proteinen |
Country Status (6)
Country | Link |
---|---|
US (1) | US5854021A (de) |
EP (1) | EP0867514B1 (de) |
JP (1) | JP4450438B2 (de) |
AT (1) | ATE539160T1 (de) |
AU (1) | AU722373B2 (de) |
CA (1) | CA2224126C (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6051401A (en) * | 1998-07-28 | 2000-04-18 | Bayer Corporation | Methods and constructs for protein expression |
US6180108B1 (en) * | 1998-12-10 | 2001-01-30 | Bayer Corporation | Vectors having terminal repeat sequence of Epstein-Barr virus |
US7723102B2 (en) | 2000-09-28 | 2010-05-25 | Bayer Corporation | Enhanced transfection system |
JP5727790B2 (ja) | 2007-12-27 | 2015-06-03 | バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated | 細胞培養プロセス |
US9700486B2 (en) | 2013-04-24 | 2017-07-11 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2197321B (en) * | 1986-09-12 | 1990-10-03 | Genentech Inc | Method and vectors for obtaining continuous production of heterologous protein in a eukaryotic host cell line |
DE69433925T2 (de) * | 1993-06-10 | 2005-07-28 | Bayer Corp. | Vektoren und Zelllinien von Säugetieren mit erhöhter Produktivität |
-
1997
- 1997-02-28 US US08/807,415 patent/US5854021A/en not_active Expired - Lifetime
-
1998
- 1998-02-11 CA CA002224126A patent/CA2224126C/en not_active Expired - Fee Related
- 1998-02-16 AT AT98102626T patent/ATE539160T1/de active
- 1998-02-16 EP EP98102626A patent/EP0867514B1/de not_active Expired - Lifetime
- 1998-02-23 JP JP05573598A patent/JP4450438B2/ja not_active Expired - Fee Related
- 1998-02-26 AU AU56345/98A patent/AU722373B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
CA2224126A1 (en) | 1998-08-28 |
CA2224126C (en) | 2008-10-07 |
US5854021A (en) | 1998-12-29 |
AU722373B2 (en) | 2000-08-03 |
AU5634598A (en) | 1998-09-03 |
JPH10248584A (ja) | 1998-09-22 |
EP0867514A2 (de) | 1998-09-30 |
EP0867514B1 (de) | 2011-12-28 |
JP4450438B2 (ja) | 2010-04-14 |
EP0867514A3 (de) | 1999-12-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69528061T2 (de) | Gereinigte polyporus laccasen und dafür kodierende nukleinsäuren | |
DE69738586D1 (de) | Hohe expressionsrate von proteinen | |
ATE439592T1 (de) | Proteingerüste für antikörper-nachahmer und andere bindende proteine | |
ATE506374T1 (de) | Exprimierungskontrolle unter verwendung von variabelen intergenischen sequenzen | |
DK0815245T3 (da) | Bioaktive IL 12 fusionsproteiner | |
DE69523052T2 (de) | Gereinigte myceliophthora laccasen und nukleinsäuren dafür kodierend | |
FI960888A0 (fi) | Protokadheriiniproteiineja ja niiden käyttö | |
DK1346034T3 (da) | von Willebrand-faktor (vWF) spaltende protease-polypeptid, nukleinsyre kodende for polypeptidet og anvendelse af polypeptidet | |
DE50012831D1 (de) | Verfahren zur verbindung von molekularen substanzen | |
DE69433925D1 (de) | Vektoren und Zelllinien von Säugetieren mit erhöhter Produktivität | |
DE59711375D1 (de) | Verfahren zur aktivierung von denaturiertem protein | |
ES2104596T3 (es) | Nuevos polipeptidos, secuencias de adn que permiten su expresion, metodo de preparacion, y utilizacion. | |
ATE539160T1 (de) | Verfahren zur erhöhung der produktion von proteinen | |
DE69737651D1 (de) | Cortistatin: neuropeptide, zusammensetzungen und methoden | |
NO930428L (no) | Proteinstrukturen til plantetoksingelonin | |
DE69902796T2 (de) | Verfahren zur reinigung von biomolekül- oder proteinkomplexen | |
DE69809227D1 (de) | Reifen mit geodätischer karkasse und verfahren zur herstellung | |
DE3586830D1 (de) | Verfahren zur ligation von heterogenen genen. | |
ATE319841T1 (de) | Verfahren zur expression von fremdgenen und entsprechende vektoren | |
NO885154L (no) | Fremgangsmaate til selektiv spalting av fusjonsproteiner. | |
DE59310280D1 (de) | Verfahren zur Herstellung von Konjugaten aus einem spezifischen Bindungspartner und einem kohlenhydrathaltigen Protein | |
DE69838459D1 (de) | Für den licht-überempfinlichkeitsphaenotyp kodierende nukleotidsequenzen von tomaten, dadurch kodierte proteine und deren verwendungen | |
DE69623746T2 (de) | Icam-4 material und verfahren | |
DE69634297D1 (de) | Verfahren zur verlängerung der expression eines interessierenden gens unter verwendung von löslichen ctla4 molekülen |