ATE539160T1 - Verfahren zur erhöhung der produktion von proteinen - Google Patents

Verfahren zur erhöhung der produktion von proteinen

Info

Publication number
ATE539160T1
ATE539160T1 AT98102626T AT98102626T ATE539160T1 AT E539160 T1 ATE539160 T1 AT E539160T1 AT 98102626 T AT98102626 T AT 98102626T AT 98102626 T AT98102626 T AT 98102626T AT E539160 T1 ATE539160 T1 AT E539160T1
Authority
AT
Austria
Prior art keywords
proteins
promoter
increase production
coding sequence
sequence
Prior art date
Application number
AT98102626T
Other languages
English (en)
Inventor
Myung-Sam Cho
Original Assignee
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Corp filed Critical Bayer Corp
Application granted granted Critical
Publication of ATE539160T1 publication Critical patent/ATE539160T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT98102626T 1997-02-28 1998-02-16 Verfahren zur erhöhung der produktion von proteinen ATE539160T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/807,415 US5854021A (en) 1997-02-28 1997-02-28 Enhance protein production method

Publications (1)

Publication Number Publication Date
ATE539160T1 true ATE539160T1 (de) 2012-01-15

Family

ID=25196326

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98102626T ATE539160T1 (de) 1997-02-28 1998-02-16 Verfahren zur erhöhung der produktion von proteinen

Country Status (6)

Country Link
US (1) US5854021A (de)
EP (1) EP0867514B1 (de)
JP (1) JP4450438B2 (de)
AT (1) ATE539160T1 (de)
AU (1) AU722373B2 (de)
CA (1) CA2224126C (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6051401A (en) * 1998-07-28 2000-04-18 Bayer Corporation Methods and constructs for protein expression
US6180108B1 (en) * 1998-12-10 2001-01-30 Bayer Corporation Vectors having terminal repeat sequence of Epstein-Barr virus
US7723102B2 (en) 2000-09-28 2010-05-25 Bayer Corporation Enhanced transfection system
DK2235197T3 (en) 2007-12-27 2017-10-09 Baxalta GmbH Methods of cell culture
US9700486B2 (en) 2013-04-24 2017-07-11 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2197321B (en) * 1986-09-12 1990-10-03 Genentech Inc Method and vectors for obtaining continuous production of heterologous protein in a eukaryotic host cell line
EP0629700A3 (de) * 1993-06-10 1995-02-15 Miles Inc Vektor und Zelllinien von Säugetieren, die eine erhöhte Produktivität aufweisen.

Also Published As

Publication number Publication date
US5854021A (en) 1998-12-29
JPH10248584A (ja) 1998-09-22
JP4450438B2 (ja) 2010-04-14
EP0867514A3 (de) 1999-12-08
EP0867514B1 (de) 2011-12-28
CA2224126C (en) 2008-10-07
EP0867514A2 (de) 1998-09-30
AU722373B2 (en) 2000-08-03
CA2224126A1 (en) 1998-08-28
AU5634598A (en) 1998-09-03

Similar Documents

Publication Publication Date Title
DE69528061T2 (de) Gereinigte polyporus laccasen und dafür kodierende nukleinsäuren
DE69738586D1 (de) Hohe expressionsrate von proteinen
ATE439592T1 (de) Proteingerüste für antikörper-nachahmer und andere bindende proteine
ATE506374T1 (de) Exprimierungskontrolle unter verwendung von variabelen intergenischen sequenzen
GB9715660D0 (en) Proteins
ATE263841T1 (de) Praktische in vitro sialylierung von rekombinanten glykpproteinen
DK0815245T3 (da) Bioaktive IL 12 fusionsproteiner
DE69523052D1 (de) Gereinigte myceliophthora laccasen und nukleinsäuren dafür kodierend
FI960888A (fi) Protokadheriiniproteiineja ja niiden käyttö
DE69433925D1 (de) Vektoren und Zelllinien von Säugetieren mit erhöhter Produktivität
ATE260972T1 (de) Verfahren zur aktivierung von denaturiertem protein
ES2104596T3 (es) Nuevos polipeptidos, secuencias de adn que permiten su expresion, metodo de preparacion, y utilizacion.
ATE539160T1 (de) Verfahren zur erhöhung der produktion von proteinen
DE69737651D1 (de) Cortistatin: neuropeptide, zusammensetzungen und methoden
NO930428L (no) Proteinstrukturen til plantetoksingelonin
ATE223491T1 (de) Verfahren zur reinigung von biomolekül- oder proteinkomplexen
DE69809227T2 (de) Reifen mit geodätischer karkasse und verfahren zur herstellung
ATE78873T1 (de) Verfahren zur selektiven spaltung von fusionsproteinen.
DE3586830D1 (de) Verfahren zur ligation von heterogenen genen.
ATE319841T1 (de) Verfahren zur expression von fremdgenen und entsprechende vektoren
DE59310280D1 (de) Verfahren zur Herstellung von Konjugaten aus einem spezifischen Bindungspartner und einem kohlenhydrathaltigen Protein
DE69838459D1 (de) Für den licht-überempfinlichkeitsphaenotyp kodierende nukleotidsequenzen von tomaten, dadurch kodierte proteine und deren verwendungen
DE69623746D1 (de) Icam-4 material und verfahren