ATE535243T1 - Prophylaktisches oder therapeutisches mittel für posteriore augenerkrankung mit selektivem nicht- ergot-d2-rezeptoragonist als wirkstoff - Google Patents
Prophylaktisches oder therapeutisches mittel für posteriore augenerkrankung mit selektivem nicht- ergot-d2-rezeptoragonist als wirkstoffInfo
- Publication number
- ATE535243T1 ATE535243T1 AT08752538T AT08752538T ATE535243T1 AT E535243 T1 ATE535243 T1 AT E535243T1 AT 08752538 T AT08752538 T AT 08752538T AT 08752538 T AT08752538 T AT 08752538T AT E535243 T1 ATE535243 T1 AT E535243T1
- Authority
- AT
- Austria
- Prior art keywords
- therapeutic agent
- prophylactic
- receptor agonist
- ergot
- active ingredient
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 3
- 230000000069 prophylactic effect Effects 0.000 title abstract 3
- 229940124597 therapeutic agent Drugs 0.000 title abstract 3
- 239000000018 receptor agonist Substances 0.000 title abstract 2
- 229940044601 receptor agonist Drugs 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title 1
- 208000030533 eye disease Diseases 0.000 title 1
- 208000022873 Ocular disease Diseases 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 206010012688 Diabetic retinal oedema Diseases 0.000 abstract 1
- 206010012689 Diabetic retinopathy Diseases 0.000 abstract 1
- 206010029113 Neovascularisation Diseases 0.000 abstract 1
- 206010064930 age-related macular degeneration Diseases 0.000 abstract 1
- 230000005779 cell damage Effects 0.000 abstract 1
- 208000037887 cell injury Diseases 0.000 abstract 1
- 210000003161 choroid Anatomy 0.000 abstract 1
- 201000011190 diabetic macular edema Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 208000002780 macular degeneration Diseases 0.000 abstract 1
- 210000000608 photoreceptor cell Anatomy 0.000 abstract 1
- FASDKYOPVNHBLU-ZETCQYMHSA-N pramipexole Chemical compound C1[C@@H](NCCC)CCC2=C1SC(N)=N2 FASDKYOPVNHBLU-ZETCQYMHSA-N 0.000 abstract 1
- 229960003089 pramipexole Drugs 0.000 abstract 1
- 210000001525 retina Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007126232 | 2007-05-11 | ||
| PCT/JP2008/058655 WO2008140051A1 (ja) | 2007-05-11 | 2008-05-09 | 非麦角系の選択的ｄ２受容体アゴニストを有効成分として含有する後眼部疾患の予防又は治療剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE535243T1 true ATE535243T1 (de) | 2011-12-15 |
Family
ID=40002247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08752538T ATE535243T1 (de) | 2007-05-11 | 2008-05-09 | Prophylaktisches oder therapeutisches mittel für posteriore augenerkrankung mit selektivem nicht- ergot-d2-rezeptoragonist als wirkstoff |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20100130569A1 (de) |
| EP (1) | EP2156833B1 (de) |
| JP (2) | JP2008308488A (de) |
| KR (1) | KR20100016270A (de) |
| CN (1) | CN101678006A (de) |
| AT (1) | ATE535243T1 (de) |
| CA (1) | CA2686394A1 (de) |
| ES (1) | ES2374336T3 (de) |
| RU (1) | RU2470635C2 (de) |
| WO (2) | WO2008140051A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI320783B (en) | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
| US8518926B2 (en) | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
| PL2026803T3 (pl) | 2006-05-16 | 2012-05-31 | Knopp Neurosciences Inc | Kompozycje R(+) i S(-) pramipeksolu i sposoby ich zastosowania |
| US8524695B2 (en) | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
| EP2137171A4 (de) | 2007-03-14 | 2010-05-19 | Knopp Neurosciences Inc | Synthese von chiralaufgereinigten substituierten benzothiazoldiaminen |
| US20110190356A1 (en) | 2008-08-19 | 2011-08-04 | Knopp Neurosciences Inc. | Compositions and Methods of Using (R)- Pramipexole |
| EA201400064A1 (ru) * | 2011-06-28 | 2014-05-30 | Байер Хелфкеэ Ллк | Офтальмологическая фармацевтическая композиция для местного применения, которая содержит регорафениб |
| JO3753B1 (ar) * | 2011-10-14 | 2021-01-31 | Otsuka Pharma Co Ltd | قرص يتألف من 7-[4-(4-بينزو[بي]ثيوفين-4-ايل-ببرازين-1-1ايل)بوتكسيل]-1اتش-كوينولين-2-وان أو ملح منه |
| US9512096B2 (en) | 2011-12-22 | 2016-12-06 | Knopp Biosciences, LLP | Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
| US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| HRP20251187T1 (hr) | 2013-07-12 | 2025-11-21 | Areteia Therapeutics, Inc. | Liječenje povišenih razina eozinofila i/ili bazofila |
| US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
| US9642840B2 (en) | 2013-08-13 | 2017-05-09 | Knopp Biosciences, Llc | Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders |
| US9763918B2 (en) | 2013-08-13 | 2017-09-19 | Knopp Biosciences Llc | Compositions and methods for treating chronic urticaria |
| PL3052194T3 (pl) * | 2013-09-30 | 2021-12-13 | Orion Corporation | Weterynaryjny sposób wywoływania wymiotów |
| EP2870965A1 (de) * | 2013-11-06 | 2015-05-13 | Sanovel Ilac Sanayi ve Ticaret A.S. | Orale flüssige pharmazeutische Formulierungen von Pramipexol |
| RU2598348C1 (ru) * | 2015-09-23 | 2016-09-20 | Федеральное государственное бюджетное учреждение "Московский научно-исследовательский институт глазных болезней имени Гельмгольца" Министерства здравоохранения Российской Федерации | Способ лечения экспериментальной ретинопатии недоношенных |
| PL232974B1 (pl) * | 2015-12-09 | 2019-08-30 | Ofta Spolka Z Ograniczona Odpowiedzialnoscia | Zastosowanie agonistów receptorów dopaminergicznych typu 2 w leczeniu schorzeń oczu wywołanych przez podwyższony poziom śródbłonkopochodnego czynnika wzrostu naczyń |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4386098A (en) * | 1981-11-03 | 1983-05-31 | Merck & Co., Inc. | 6-Hydroxy-2-benzothiazolesulfonamide for the topical treatment of elevated intraocular pressure |
| US4452808A (en) * | 1982-12-07 | 1984-06-05 | Smithkline Beckman Corporation | 4-Aminoalkyl-2(3H)-indolones |
| DE3447075A1 (de) | 1984-12-22 | 1986-07-03 | Dr. Karl Thomae Gmbh, 7950 Biberach | Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arzneimittel |
| DE3923689A1 (de) * | 1989-07-18 | 1991-01-24 | Boehringer Ingelheim Kg | Neue verwendung von tetrahydrobenzthiazolderivaten als arzneistoffe |
| US5731294A (en) * | 1993-07-27 | 1998-03-24 | Hybridon, Inc. | Inhibition of neovasularization using VEGF-specific oligonucleotides |
| KR100840727B1 (ko) * | 1999-12-02 | 2008-06-23 | 오에스아이 파마슈티컬스, 인코포레이티드 | 아데노신 ａ1, ａ2ａ 및 ａ3 수용체 특이 화합물 및 그의 사용방법 |
| GB0106661D0 (en) * | 2001-03-16 | 2001-05-09 | Pfizer Ltd | Pharmaceutically active compounds |
| HRP20040406A2 (en) * | 2001-11-09 | 2005-02-28 | Eyetech Pharmaceuticals | Methods for treating ocular neovascular diseases |
| JP2004323486A (ja) * | 2003-04-30 | 2004-11-18 | National Institute Of Advanced Industrial & Technology | 網膜及び／又はブドウ膜疾患の予防乃至治療用点眼薬 |
| UY28326A1 (es) * | 2003-05-22 | 2004-06-30 | Osmotica Argentina S A | Dispositivo de ruptura de liberacion controlada con un pasaje preformado |
| JP2006176499A (ja) * | 2004-11-25 | 2006-07-06 | Nippon Seibutsu Seizai:Kk | 眼疾患治療剤 |
| ES2334061T3 (es) * | 2005-08-15 | 2010-03-04 | University Of Virginia Patent Foundation | Neurorrestauracion con pramipexol r(+). |
| WO2007121188A2 (en) * | 2006-04-10 | 2007-10-25 | Knopp Neurosciences, Inc. | Compositions and methods of using r(+) pramipexole |
-
2008
- 2008-05-09 WO PCT/JP2008/058655 patent/WO2008140051A1/ja not_active Ceased
- 2008-05-09 WO PCT/JP2008/058657 patent/WO2008140052A1/ja not_active Ceased
- 2008-05-09 RU RU2009145939/15A patent/RU2470635C2/ru not_active IP Right Cessation
- 2008-05-09 JP JP2008123636A patent/JP2008308488A/ja not_active Abandoned
- 2008-05-09 JP JP2008123639A patent/JP2008308489A/ja not_active Withdrawn
- 2008-05-09 US US12/451,282 patent/US20100130569A1/en not_active Abandoned
- 2008-05-09 CN CN200880015685A patent/CN101678006A/zh active Pending
- 2008-05-09 AT AT08752538T patent/ATE535243T1/de active
- 2008-05-09 KR KR1020097023170A patent/KR20100016270A/ko not_active Ceased
- 2008-05-09 EP EP08752538A patent/EP2156833B1/de not_active Not-in-force
- 2008-05-09 CA CA002686394A patent/CA2686394A1/en not_active Abandoned
- 2008-05-09 ES ES08752538T patent/ES2374336T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2686394A1 (en) | 2008-11-20 |
| EP2156833B1 (de) | 2011-11-30 |
| RU2009145939A (ru) | 2011-06-20 |
| JP2008308489A (ja) | 2008-12-25 |
| EP2156833A4 (de) | 2010-11-24 |
| EP2156833A1 (de) | 2010-02-24 |
| RU2470635C2 (ru) | 2012-12-27 |
| ES2374336T3 (es) | 2012-02-15 |
| WO2008140051A1 (ja) | 2008-11-20 |
| KR20100016270A (ko) | 2010-02-12 |
| JP2008308488A (ja) | 2008-12-25 |
| WO2008140052A1 (ja) | 2008-11-20 |
| CN101678006A (zh) | 2010-03-24 |
| US20100130569A1 (en) | 2010-05-27 |
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