ATE530914T1 - Prionentest - Google Patents

Prionentest

Info

Publication number
ATE530914T1
ATE530914T1 AT08754072T AT08754072T ATE530914T1 AT E530914 T1 ATE530914 T1 AT E530914T1 AT 08754072 T AT08754072 T AT 08754072T AT 08754072 T AT08754072 T AT 08754072T AT E530914 T1 ATE530914 T1 AT E530914T1
Authority
AT
Austria
Prior art keywords
prpsc
protease
region
binding partner
prpc
Prior art date
Application number
AT08754072T
Other languages
English (en)
Inventor
David Peretz
Alice Yam
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE530914T1 publication Critical patent/ATE530914T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT08754072T 2007-04-04 2008-04-03 Prionentest ATE530914T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92195107P 2007-04-04 2007-04-04
US6670408P 2008-02-21 2008-02-21
PCT/US2008/004454 WO2008124098A1 (en) 2007-04-04 2008-04-03 Prion assay

Publications (1)

Publication Number Publication Date
ATE530914T1 true ATE530914T1 (de) 2011-11-15

Family

ID=39639387

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08754072T ATE530914T1 (de) 2007-04-04 2008-04-03 Prionentest

Country Status (7)

Country Link
US (1) US20100196934A1 (de)
EP (1) EP2142934B1 (de)
JP (1) JP2010523977A (de)
AT (1) ATE530914T1 (de)
CA (1) CA2684796A1 (de)
ES (1) ES2373762T3 (de)
WO (1) WO2008124098A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2140272A1 (de) * 2007-04-04 2010-01-06 Novartis Ag Prion-elisa
WO2010084201A1 (en) 2009-01-26 2010-07-29 Commissariat A L'energie Atomique Et Aux Energies Alternatives Novel derivative of erythromycin for the treatment and diagnosis of prion disease
US9739771B2 (en) * 2009-02-27 2017-08-22 Yale University Physiologic sample preparation for nanosensors
EP3406632A1 (de) 2017-05-23 2018-11-28 S.I.S.S.A. Scuola Internazionale Superiore di Studi Avanzati An prionprotein bindende liganden zur verwendung bei der behandlung von synukleinopathien

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6165784A (en) * 1997-10-14 2000-12-26 The United States Of America As Represented By The Secretary Of Agriculture Antibodies for the detection of prion protein as an indication of transmissible spongiform encephalopathies
US6214565B1 (en) * 1998-10-09 2001-04-10 The Regents Of The University Of California Assay for disease related conformation of a protein and isolating same
US6261790B1 (en) * 1999-07-15 2001-07-17 The United States Of America As Represented By The Secretary Of Agriculture Monoclonal antibodies and antibody cocktail for detection of prion protein as an indication of transmissible spongiform encephalopathies
FR2801106B1 (fr) * 1999-11-12 2007-10-05 Commissariat Energie Atomique Procede de diagnostic d'une esst provoquee par une souche d'atnc dans un echantillon biologique et son utilisation dans le diagnostic differentiel des differentes souches d'atnc
DE10152677A1 (de) * 2001-10-19 2003-05-08 Aventis Behring Gmbh Antikörper zum spezifischen Nachweis von pathogenen Prionen humanen Ursprungs und damit durchgeführten Nachweisverfahren
FR2842303B1 (fr) * 2002-07-09 2004-09-24 Commissariat Energie Atomique Methode de detection automatisable de la prpres et ses applications
US20060035242A1 (en) * 2004-08-13 2006-02-16 Michelitsch Melissa D Prion-specific peptide reagents
EP1653844B1 (de) * 2003-08-13 2012-12-12 Novartis Vaccines and Diagnostics, Inc. Prion-spezifische peptid-reagenzien
JP5162250B2 (ja) * 2005-01-13 2013-03-13 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド プリオン特異的ペプチド試薬を使用するｅｌｉｓａアッセイ
CA2598321A1 (en) * 2005-02-19 2006-08-24 Peoplebio, Inc. Method for differentially detecting multimeric form from monomeric form of multimer-forming polypeptides
JP4724816B2 (ja) * 2005-09-06 2011-07-13 シャープ株式会社 タンパク質の測定方法
KR20080048527A (ko) * 2005-09-09 2008-06-02 노파르티스 아게 프리온-특이적 펩토이드 시약

Also Published As

Publication number Publication date
US20100196934A1 (en) 2010-08-05
EP2142934B1 (de) 2011-10-26
ES2373762T3 (es) 2012-02-08
EP2142934A1 (de) 2010-01-13
WO2008124098A1 (en) 2008-10-16
CA2684796A1 (en) 2008-10-16
JP2010523977A (ja) 2010-07-15

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Legal Events

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