ATE520421T1 - Radioaktiv markierte brückenkopf-verbindungen und verfahren zu ihrer verwendung - Google Patents

Radioaktiv markierte brückenkopf-verbindungen und verfahren zu ihrer verwendung

Info

Publication number
ATE520421T1
ATE520421T1 AT06734176T AT06734176T ATE520421T1 AT E520421 T1 ATE520421 T1 AT E520421T1 AT 06734176 T AT06734176 T AT 06734176T AT 06734176 T AT06734176 T AT 06734176T AT E520421 T1 ATE520421 T1 AT E520421T1
Authority
AT
Austria
Prior art keywords
bridgehead
connections
bfr
radioactively marked
radioactively
Prior art date
Application number
AT06734176T
Other languages
English (en)
Inventor
Jacobus Donatus Herscheid
Joost Verbeek
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Application granted granted Critical
Publication of ATE520421T1 publication Critical patent/ATE520421T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06734176T 2005-02-02 2006-01-30 Radioaktiv markierte brückenkopf-verbindungen und verfahren zu ihrer verwendung ATE520421T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05075259 2005-02-02
PCT/US2006/003600 WO2006083983A2 (en) 2005-02-02 2006-01-30 Bridgehead radiolabelled compounds and methods of using the same

Publications (1)

Publication Number Publication Date
ATE520421T1 true ATE520421T1 (de) 2011-09-15

Family

ID=36603661

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06734176T ATE520421T1 (de) 2005-02-02 2006-01-30 Radioaktiv markierte brückenkopf-verbindungen und verfahren zu ihrer verwendung

Country Status (12)

Country Link
US (1) US7901667B2 (de)
EP (1) EP1846043B1 (de)
JP (1) JP5128293B2 (de)
CN (1) CN101111270A (de)
AT (1) ATE520421T1 (de)
AU (1) AU2006210791A1 (de)
BR (1) BRPI0606983A2 (de)
CA (1) CA2593323C (de)
ES (1) ES2371487T3 (de)
IL (1) IL184988A0 (de)
RU (1) RU2007129225A (de)
WO (1) WO2006083983A2 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5609849A (en) * 1994-03-11 1997-03-11 The Trustees Of The University Of Pennsylvania Serotonin (5-HT1A) receptor ligands and imaging agents
US5605809A (en) * 1994-10-28 1997-02-25 Oncoimmunin, Inc. Compositions for the detection of proteases in biological samples and methods of use thereof
EP1022049A1 (de) 1999-01-22 2000-07-26 Mallinckrodt Medical, Inc. Verfahren zur Reinigung und Konzentration von Radiojod Isotopen
EP1276731A2 (de) 1999-11-12 2003-01-22 Wyeth Verzweigte adamantyl- und noradamantyl-, aryl- und aralkyl-piperazine mit 5-ht1a serotoninergischer aktivität

Also Published As

Publication number Publication date
CN101111270A (zh) 2008-01-23
WO2006083983A3 (en) 2007-04-26
CA2593323A1 (en) 2006-08-10
EP1846043A2 (de) 2007-10-24
BRPI0606983A2 (pt) 2009-07-28
EP1846043B1 (de) 2011-08-17
IL184988A0 (en) 2007-12-03
CA2593323C (en) 2014-05-27
AU2006210791A1 (en) 2006-08-10
JP2008538545A (ja) 2008-10-30
US20080161542A1 (en) 2008-07-03
WO2006083983A2 (en) 2006-08-10
ES2371487T3 (es) 2012-01-03
RU2007129225A (ru) 2009-03-10
JP5128293B2 (ja) 2013-01-23
US7901667B2 (en) 2011-03-08

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties