ATE519504T1 - Chromatin-remodellierende substanzen zur erhöhung der expression von pdx-1 und förderung der zelldifferenzierung - Google Patents
Chromatin-remodellierende substanzen zur erhöhung der expression von pdx-1 und förderung der zelldifferenzierungInfo
- Publication number
- ATE519504T1 ATE519504T1 AT06254532T AT06254532T ATE519504T1 AT E519504 T1 ATE519504 T1 AT E519504T1 AT 06254532 T AT06254532 T AT 06254532T AT 06254532 T AT06254532 T AT 06254532T AT E519504 T1 ATE519504 T1 AT E519504T1
- Authority
- AT
- Austria
- Prior art keywords
- pdx
- substances
- cell differentiation
- promote cell
- increase expression
- Prior art date
Links
- 230000024245 cell differentiation Effects 0.000 title abstract 2
- 108010077544 Chromatin Proteins 0.000 title 1
- 102100041030 Pancreas/duodenum homeobox protein 1 Human genes 0.000 title 1
- 101710144033 Pancreas/duodenum homeobox protein 1 Proteins 0.000 title 1
- 210000003483 chromatin Anatomy 0.000 title 1
- 238000007634 remodeling Methods 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- 102000052651 Pancreatic hormone Human genes 0.000 abstract 1
- 101800001268 Pancreatic hormone Proteins 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000004025 pancreas hormone Substances 0.000 abstract 1
- 229940032957 pancreatic hormone Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
- C12N5/0678—Stem cells; Progenitor cells; Precursor cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71307205P | 2005-08-31 | 2005-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE519504T1 true ATE519504T1 (de) | 2011-08-15 |
Family
ID=37806561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06254532T ATE519504T1 (de) | 2005-08-31 | 2006-08-31 | Chromatin-remodellierende substanzen zur erhöhung der expression von pdx-1 und förderung der zelldifferenzierung |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1949916B1 (de) |
| JP (1) | JP2007061096A (de) |
| AT (1) | ATE519504T1 (de) |
| AU (1) | AU2006204630A1 (de) |
| CA (1) | CA2557635C (de) |
| ES (1) | ES2369240T3 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009127719A1 (en) * | 2008-04-18 | 2009-10-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method for obtaining ngn3-expressing cells and insulin producing-beta cells |
| WO2009157559A1 (ja) * | 2008-06-27 | 2009-12-30 | 独立行政法人産業技術総合研究所 | 膵臓疾患又は糖尿病のための膵臓細胞再生移植用キット |
| US10513685B2 (en) | 2010-03-23 | 2019-12-24 | Corning Incorporated | Method for differentiating pluripotent mammalian stem cells into a population of hepatic cells in a microchamber |
| BR112015002295B1 (pt) | 2012-07-31 | 2022-02-01 | The Board Of Regents Of The University Of Texas System | Método para induzir a formação de célula beta in vitro |
| JP6486272B2 (ja) | 2012-09-07 | 2019-03-20 | マサチューセッツ・アイ・アンド・イア・インファーマリー | 有毛細胞および／または支持細胞再生のための方法および組成物 |
| EP3212773B1 (de) | 2014-10-29 | 2021-09-15 | Massachusetts Eye and Ear Infirmary | Effiziente abgabe von therapeutischen molekülen an zellen des innenohres |
| KR101697437B1 (ko) * | 2015-10-12 | 2017-01-17 | 전남대학교병원 | 중간엽줄기세포의 심근유사세포 분화유도용 아피시딘 함유 조성물 |
| US11590152B2 (en) | 2018-01-26 | 2023-02-28 | Massachusetts Eye And Ear Infirmary | Treatment of hearing loss |
| CN117957310A (zh) * | 2021-09-30 | 2024-04-30 | Jsr株式会社 | 类器官的制造方法、类器官制造用培养基、类器官、及被检物质的评价方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6774120B1 (en) * | 1999-06-01 | 2004-08-10 | Sarah Ferber | Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues |
| US20040002447A1 (en) * | 2002-06-04 | 2004-01-01 | Regents Of The University Of California | Induction of insulin expression |
-
2006
- 2006-08-30 JP JP2006234037A patent/JP2007061096A/ja active Pending
- 2006-08-30 CA CA2557635A patent/CA2557635C/en not_active Expired - Fee Related
- 2006-08-31 AU AU2006204630A patent/AU2006204630A1/en not_active Abandoned
- 2006-08-31 AT AT06254532T patent/ATE519504T1/de active
- 2006-08-31 EP EP06254532A patent/EP1949916B1/de not_active Not-in-force
- 2006-08-31 ES ES06254532T patent/ES2369240T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1949916A1 (de) | 2008-07-30 |
| CA2557635C (en) | 2014-10-28 |
| CA2557635A1 (en) | 2007-02-28 |
| AU2006204630A1 (en) | 2007-03-15 |
| JP2007061096A (ja) | 2007-03-15 |
| HK1118719A1 (en) | 2009-02-20 |
| ES2369240T3 (es) | 2011-11-28 |
| EP1949916B1 (de) | 2011-08-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE474592T1 (de) | Zusammensetzungen enthaltend lipase, protease und amylase zur behandlung von pankreasinsuffizienz | |
| NL301145I2 (nl) | Tirbanibulin | |
| IS3013B (is) | Meltikornatálmar og aðferðir til að nota þá | |
| DE602007011908D1 (de) | Verwendung von gpr119-rezeptoragonisten zur vermehrung der knochenmasse und zur behandlung von osteoporose sowie kombinationstherapie dafür | |
| DE602005009748D1 (de) | 3-phenyl-pyrazol-derivate als modulatoren des zur behandlung damit zusammenhängender störungen nützlichen 5-ht-2a-serotonin-rezeptors | |
| ATE524479T1 (de) | Sulfonamidthiazolpyridinderivate als zur behandlung von typ-2-diabetes geeignete glucokinaseaktivatoren | |
| ATE423087T1 (de) | Proteasome inhibitoren und deren verwendung | |
| CY1109985T1 (el) | Αναστολεις πρωτεασωματος και μεθοδοι χρησης αυτων | |
| EA200870164A1 (ru) | Лечение вирусного гепатита | |
| ATE532518T1 (de) | Dipeptidyl-peptidase-hemmer zur behandlung von diabetes | |
| TN2010000060A1 (en) | Proteasome inhibitors | |
| IL184403A0 (en) | Method and composition for treating mammalian diseases and injuries caused by the over expression of peroxynitrite | |
| ATE512663T1 (de) | Kombination zur behandlung von erkrankungen mit zellproliferation | |
| DE602005011656D1 (de) | Verfahren zur behandlung von dickdarmkrebs mit botulinum neurotoxin | |
| DE602005023877D1 (de) | Verfahren zur herstellung von 7-alpha-alkylierte 19-norsteroide | |
| EP1934025A4 (de) | Zusammensetzung zur behandlung von holz, verfahren zur behandlung von holz und holzprodukt | |
| ATE519504T1 (de) | Chromatin-remodellierende substanzen zur erhöhung der expression von pdx-1 und förderung der zelldifferenzierung | |
| DE602006010400D1 (de) | Olanzapin-analoga und verfahren zu ihrer verwendung | |
| AR059193A1 (es) | Modulacion de la actividad de mdl-1 para el tratamiento de enfermedades inflamatorias | |
| ATE399158T1 (de) | Heterocyclische phenylaminopropanolderivate als modulatoren der monoaminwiederaufnahme zur behandlung von vasomotorischen symptomen (vms) | |
| DE602005016141D1 (de) | S-mirtazapin zur behandlung von hitzewallungen | |
| EP1759020A4 (de) | Acacs als modifikatoren des igf-weges und verwendungsverfahren | |
| ATE535246T1 (de) | Zusammensetzung zur behandlung von erkrankungen des zentralen nervensystems | |
| ATE425755T1 (de) | 4-aminophenyl-morpholinon-derivate zur behandlung von hepatitis c | |
| MY180594A (en) | Proteasome inhibitors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1949916 Country of ref document: EP |