ATE518138T1 - Stabilisierung von konjugaten mit einem thiourea- binder - Google Patents
Stabilisierung von konjugaten mit einem thiourea- binderInfo
- Publication number
- ATE518138T1 ATE518138T1 AT08020499T AT08020499T ATE518138T1 AT E518138 T1 ATE518138 T1 AT E518138T1 AT 08020499 T AT08020499 T AT 08020499T AT 08020499 T AT08020499 T AT 08020499T AT E518138 T1 ATE518138 T1 AT E518138T1
- Authority
- AT
- Austria
- Prior art keywords
- thiourea
- conjugate
- conjugates
- stabilization
- binder
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07023206 | 2007-11-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE518138T1 true ATE518138T1 (de) | 2011-08-15 |
Family
ID=39271113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08020499T ATE518138T1 (de) | 2007-11-30 | 2008-11-26 | Stabilisierung von konjugaten mit einem thiourea- binder |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20110112291A1 (https=) |
| EP (1) | EP2065705B1 (https=) |
| JP (1) | JP5523695B2 (https=) |
| CN (1) | CN101445503A (https=) |
| AT (1) | ATE518138T1 (https=) |
| CA (1) | CA2645309C (https=) |
| ES (1) | ES2369717T3 (https=) |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5112930A (en) * | 1975-04-08 | 1976-01-31 | Kumiai Chemical Industry Co | Anteiseiryokonaru noengeiyosakinsoseibutsu |
| JPS5718605A (en) * | 1980-07-07 | 1982-01-30 | Kumiai Chem Ind Co Ltd | Stable insecticidal composition |
| GB2095818B (en) | 1981-03-27 | 1985-10-02 | Exxon Research Engineering Co | Staged adsorption/resorption heat pump |
| JPS5855417A (ja) * | 1981-09-27 | 1983-04-01 | Nitto Electric Ind Co Ltd | 医薬組成物 |
| WO1993002652A2 (en) * | 1991-08-01 | 1993-02-18 | Hybritech Incorporated | Modified haptens useful as imaging and therapeutic agents |
| US5541287A (en) * | 1992-06-09 | 1996-07-30 | Neorx Corporation | Pretargeting methods and compounds |
| WO1995006877A1 (en) * | 1993-09-03 | 1995-03-09 | Behringwerke Ag | Fluorescent oxygen channeling immunoassays |
| IT1298693B1 (it) * | 1996-04-24 | 2000-01-12 | Hoffmann La Roche | Derivati della fluoresceina 4'-metil sostituiti |
| US6342219B1 (en) * | 1999-04-28 | 2002-01-29 | Board Of Regents, The University Of Texas System | Antibody compositions for selectively inhibiting VEGF |
| US6586628B2 (en) * | 2000-05-10 | 2003-07-01 | The United States Of America, As Represented By The Secretary Of Agriculture | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same |
| US6586460B1 (en) | 2001-04-02 | 2003-07-01 | The Board Of Regents For Oklahoma State University | Heteroarotinoids containing urea or thiourea linker |
| US20030171260A1 (en) * | 2002-03-11 | 2003-09-11 | Nelson Deanna Jean | Compositions and methods utilizing hydroxamates to scavenge oxidant toxins |
| US7371524B2 (en) * | 2003-06-17 | 2008-05-13 | Hannjorg Hereth | Substituted azaporphyrins as fluorescence labels |
| DE102004045748A1 (de) * | 2004-09-21 | 2006-04-06 | Roche Diagnostics Gmbh | Stöchiometrisch definierte farbstoffmarkierte Substanzen zur Messung der glomerulären Filtrationsrate, ihre Herstellung und Verwendung |
| EP1795607A1 (en) * | 2005-12-08 | 2007-06-13 | Roche Diagnostics GmbH | Stabilized cholinesterase substrate solution |
| AU2006100657C4 (en) * | 2006-05-15 | 2009-09-10 | Wyeth | Stabilised formulation |
-
2008
- 2008-11-26 EP EP08020499A patent/EP2065705B1/en active Active
- 2008-11-26 ES ES08020499T patent/ES2369717T3/es active Active
- 2008-11-26 AT AT08020499T patent/ATE518138T1/de active
- 2008-11-26 US US12/323,942 patent/US20110112291A1/en not_active Abandoned
- 2008-11-27 JP JP2008302955A patent/JP5523695B2/ja active Active
- 2008-11-27 CA CA2645309A patent/CA2645309C/en active Active
- 2008-11-28 CN CNA200810179982XA patent/CN101445503A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2369717T3 (es) | 2011-12-05 |
| JP2009132716A (ja) | 2009-06-18 |
| CN101445503A (zh) | 2009-06-03 |
| JP5523695B2 (ja) | 2014-06-18 |
| US20110112291A1 (en) | 2011-05-12 |
| EP2065705B1 (en) | 2011-07-27 |
| CA2645309C (en) | 2016-07-19 |
| CA2645309A1 (en) | 2009-05-30 |
| EP2065705A1 (en) | 2009-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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