ATE510919T1 - Veränderte hirnanhangsdrüsenentwicklung in nachkommen von mit einer therapie mit wachstumshormon freisetzendem hormon behandelten trächtigen muttertieren - Google Patents

Veränderte hirnanhangsdrüsenentwicklung in nachkommen von mit einer therapie mit wachstumshormon freisetzendem hormon behandelten trächtigen muttertieren

Info

Publication number
ATE510919T1
ATE510919T1 AT03710898T AT03710898T ATE510919T1 AT E510919 T1 ATE510919 T1 AT E510919T1 AT 03710898 T AT03710898 T AT 03710898T AT 03710898 T AT03710898 T AT 03710898T AT E510919 T1 ATE510919 T1 AT E510919T1
Authority
AT
Austria
Prior art keywords
offspring
altered
pituitary gland
gland development
pregnant mothers
Prior art date
Application number
AT03710898T
Other languages
English (en)
Inventor
Ruxandra Draghia-Akli
Amir Khan
Original Assignee
Baylor College Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College Medicine filed Critical Baylor College Medicine
Application granted granted Critical
Publication of ATE510919T1 publication Critical patent/ATE510919T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth-hormone releasing factors (GH-RF) (Somatoliberin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
AT03710898T 2002-02-07 2003-02-06 Veränderte hirnanhangsdrüsenentwicklung in nachkommen von mit einer therapie mit wachstumshormon freisetzendem hormon behandelten trächtigen muttertieren ATE510919T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35556602P 2002-02-07 2002-02-07
PCT/US2003/003640 WO2003066825A2 (en) 2002-02-07 2003-02-06 Modified pituitary gland development in offspring from expectant mother animals treated with growth hormone releasing hormone therapy

Publications (1)

Publication Number Publication Date
ATE510919T1 true ATE510919T1 (de) 2011-06-15

Family

ID=27734536

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03710898T ATE510919T1 (de) 2002-02-07 2003-02-06 Veränderte hirnanhangsdrüsenentwicklung in nachkommen von mit einer therapie mit wachstumshormon freisetzendem hormon behandelten trächtigen muttertieren

Country Status (10)

Country Link
US (2) US7250405B2 (de)
EP (1) EP1499731B1 (de)
AR (1) AR038816A1 (de)
AT (1) ATE510919T1 (de)
AU (1) AU2003215082B2 (de)
CA (1) CA2475273A1 (de)
MX (1) MXPA04007638A (de)
NZ (1) NZ534935A (de)
TW (1) TW200307749A (de)
WO (1) WO2003066825A2 (de)

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EP1539959A2 (de) * 2002-09-18 2005-06-15 Centre Hospitalier de l'Université de Montréal (CHUM) Ghrh-analoge
CA2499533A1 (en) * 2002-09-26 2004-04-08 Pfizer Products Inc. Use of excipients to increase dna uptake by swine muscle cells
US7846720B2 (en) * 2005-01-26 2010-12-07 Vgx Pharmaceuticals, Inc. Optimized high yield synthetic plasmids
US8889632B2 (en) 2007-01-31 2014-11-18 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
CN101730708B (zh) 2007-03-28 2013-09-18 哈佛大学校长及研究员协会 缝合多肽
KR100944034B1 (ko) 2007-04-19 2010-02-24 한올제약주식회사 프로테아제-내성 폴리펩티드의 경구 투여 제형
CA2807685C (en) 2010-08-13 2020-10-06 Aileron Therapeutics, Inc. P53 derived peptidomimetic macrocycle
US9096684B2 (en) 2011-10-18 2015-08-04 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
US8993316B2 (en) 2011-11-16 2015-03-31 Brian P. Hanley Methods and compositions for gene therapy and GHRH therapy
JP6450192B2 (ja) 2012-02-15 2019-01-09 エイルロン セラピューティクス，インコーポレイテッド トリアゾール架橋した、およびチオエーテル架橋したペプチドミメティック大環状化合物
WO2013123266A1 (en) 2012-02-15 2013-08-22 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
US9604919B2 (en) 2012-11-01 2017-03-28 Aileron Therapeutics, Inc. Disubstituted amino acids and methods of preparation and use thereof
AU2015320549A1 (en) 2014-09-24 2017-04-13 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
BR112017019738A2 (pt) 2015-03-20 2018-05-29 Aileron Therapeutics Inc macrociclos peptidomiméticos e usos dos mesmos

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US4226857A (en) 1979-03-30 1980-10-07 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4223019A (en) 1979-03-30 1980-09-16 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4228158A (en) 1979-03-30 1980-10-14 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4228156A (en) 1979-03-30 1980-10-14 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4224316A (en) 1979-03-30 1980-09-23 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4223020A (en) 1979-03-30 1980-09-16 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4223021A (en) 1979-03-30 1980-09-16 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4410512A (en) 1981-12-28 1983-10-18 Beckman Instruments, Inc. Combinations having synergistic pituitary growth hormone releasing activity
US5134120A (en) 1984-08-03 1992-07-28 Cornell Research Foundation, Inc. Use of growth hormone to enhance porcine weight gain
US5036045A (en) 1985-09-12 1991-07-30 The University Of Virginia Alumni Patents Foundation Method for increasing growth hormone secretion
US4833166A (en) 1987-05-01 1989-05-23 Grosvenor Clark E Growth hormone releasing hormone complementary peptides
US4839344A (en) 1987-06-12 1989-06-13 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
USRE33699E (en) 1987-07-09 1991-09-24 International Minerals & Chemical Corp. Growth hormone-releasing factor analogs
FR2622455B1 (fr) 1987-11-04 1991-07-12 Agronomique Inst Nat Rech Application du facteur de stimulation de la secretion de l'hormone de croissance humaine, de ses fragments actifs et des analogues correspondants, pour augmenter la production laitiere et le poids des nouveau-nes chez les mammiferes
US5605885A (en) 1988-05-05 1997-02-25 Entremed, Inc. Method for stimulating the immune system
US5023322A (en) 1988-08-31 1991-06-11 Mta Kutatas-Es Szervezetelemzo Intezete Analogs of growth hormone releasing factor (GRF) and a method for the preparation thereof
US5084442A (en) 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5137872A (en) 1989-09-18 1992-08-11 Pitman-Moore, Inc. Growth hormone-releasing factor analogs
AU656144B2 (en) 1990-06-29 1995-01-27 F. Hoffmann-La Roche Ag Histidine substituted growth hormone releasing factor analogs
US5486505A (en) 1990-07-24 1996-01-23 Polygen Holding Corporation Polypeptide compounds having growth hormone releasing activity
EP0525838A3 (de) 1991-04-09 1993-02-10 F. Hoffmann-La Roche Ag Analogen von Wachstum-Hormon-befreundem Hormon
US5663146A (en) 1991-08-22 1997-09-02 Administrators Of The Tulane Educational Fund Polypeptide analogues having growth hormone releasing activity
US5298422A (en) 1991-11-06 1994-03-29 Baylor College Of Medicine Myogenic vector systems
US5696128A (en) 1994-07-07 1997-12-09 The Board Of Supervisors Of Louisiana University And Agricultural And Mechanical College Method of regulating immune function
US5792747A (en) 1995-01-24 1998-08-11 The Administrators Of The Tulane Educational Fund Highly potent agonists of growth hormone releasing hormone
WO1996032126A1 (en) 1995-04-14 1996-10-17 The Administrators Of The Tulane Educational Fund Analogs of growth hormone-releasing factor
US5801224A (en) * 1996-04-26 1998-09-01 Board Of Trustees Operating Michigan State University Bulk reactive extrusion polymerization process producing aliphatic ester polymer compositions
KR20020047096A (ko) * 1999-07-26 2002-06-21 크로커 사무엘 에스 초활성 돼지 성장 호르몬 분비 호르몬 유사체
AR035671A1 (es) * 2000-12-12 2004-06-23 Advisys Inc Administracion de secuencia de acido nucleico a un animal hembra, para aumentar el crecimiento de la descendencia
AU2002348417B9 (en) * 2001-10-26 2010-02-04 Baylor College Of Medicine A composition and method to alter lean body mass and bone properties in a subject
EP1465654B1 (de) * 2001-12-11 2015-02-25 Inovio Pharmaceuticals, Inc. Durch plasmid übertragene supplementierung zur behandlung chronisch kranker patienten

Also Published As

Publication number Publication date
US7250405B2 (en) 2007-07-31
US20080207543A1 (en) 2008-08-28
EP1499731A2 (de) 2005-01-26
AU2003215082A1 (en) 2003-09-02
AU2003215082B2 (en) 2011-11-10
AR038816A1 (es) 2005-01-26
US20040038918A1 (en) 2004-02-26
MXPA04007638A (es) 2004-12-06
CA2475273A1 (en) 2003-08-14
EP1499731A4 (de) 2006-04-26
EP1499731B1 (de) 2011-05-25
TW200307749A (en) 2003-12-16
WO2003066825A2 (en) 2003-08-14
WO2003066825A3 (en) 2004-10-28
NZ534935A (en) 2010-04-30

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