ATE502919T1 - Kupplungsmittel, deren aktive zwischenverbindungen und konjugate sowie die verwendung dieser konjugate für diagnostische zwecke - Google Patents

Kupplungsmittel, deren aktive zwischenverbindungen und konjugate sowie die verwendung dieser konjugate für diagnostische zwecke

Info

Publication number
ATE502919T1
ATE502919T1 AT03718910T AT03718910T ATE502919T1 AT E502919 T1 ATE502919 T1 AT E502919T1 AT 03718910 T AT03718910 T AT 03718910T AT 03718910 T AT03718910 T AT 03718910T AT E502919 T1 ATE502919 T1 AT E502919T1
Authority
AT
Austria
Prior art keywords
mal
conjugates
new
molecule
iii
Prior art date
Application number
AT03718910T
Other languages
English (en)
Inventor
Xavier Lacoux
Original Assignee
Biomerieux Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux Sa filed Critical Biomerieux Sa
Application granted granted Critical
Publication of ATE502919T1 publication Critical patent/ATE502919T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
    • C07D207/452—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
AT03718910T 2002-02-28 2003-02-26 Kupplungsmittel, deren aktive zwischenverbindungen und konjugate sowie die verwendung dieser konjugate für diagnostische zwecke ATE502919T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0202559A FR2836382B1 (fr) 2002-02-28 2002-02-28 Nouveaux agents de couplages, leurs conjugues, ainsi que l'utilisation de ces conjugues dans des methodes de diagnostic
PCT/FR2003/000619 WO2003072546A1 (fr) 2002-02-28 2003-02-26 Nouveaux agents de couplages, leurs intermédiaires actives, leurs conjugues, ainsi que l'utilisation de ces conjugues dans des méthodes de diagnostic

Publications (1)

Publication Number Publication Date
ATE502919T1 true ATE502919T1 (de) 2011-04-15

Family

ID=27676179

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03718910T ATE502919T1 (de) 2002-02-28 2003-02-26 Kupplungsmittel, deren aktive zwischenverbindungen und konjugate sowie die verwendung dieser konjugate für diagnostische zwecke

Country Status (7)

Country Link
US (1) US7132269B2 (de)
EP (1) EP1478623B1 (de)
AT (1) ATE502919T1 (de)
AU (1) AU2003222944A1 (de)
DE (1) DE60336455D1 (de)
FR (1) FR2836382B1 (de)
WO (1) WO2003072546A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7356711B1 (en) 2002-05-30 2008-04-08 Microsoft Corporation Secure registration
FR2955111B1 (fr) * 2010-01-12 2013-05-31 Biomerieux Sa Procede de preparation de composes polybiotinyles
CN102834109B (zh) * 2010-01-22 2016-01-20 诺沃—诺迪斯克保健股份有限公司 稳定的生长激素化合物
JP5980689B2 (ja) 2010-01-22 2016-08-31 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー 安定な成長ホルモン化合物
JP6464145B2 (ja) 2013-04-05 2019-02-06 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー 成長ホルモン化合物製剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162505A (en) * 1989-09-19 1992-11-10 Centocor Proteins modified with positively charged carriers and compositions prepared therefrom
US5329028A (en) * 1992-08-05 1994-07-12 Genentech, Inc. Carbohydrate-directed cross-linking reagents
US6139819A (en) * 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use

Also Published As

Publication number Publication date
EP1478623A1 (de) 2004-11-24
EP1478623B1 (de) 2011-03-23
DE60336455D1 (de) 2011-05-05
AU2003222944A1 (en) 2003-09-09
FR2836382B1 (fr) 2004-08-13
WO2003072546A1 (fr) 2003-09-04
US7132269B2 (en) 2006-11-07
FR2836382A1 (fr) 2003-08-29
US20050215771A1 (en) 2005-09-29

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Legal Events

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