ATE502675T1 - Verbindungen, die den ampa-rezeptor verstärken, und deren anwendung in der medizin - Google Patents

Verbindungen, die den ampa-rezeptor verstärken, und deren anwendung in der medizin

Info

Publication number
ATE502675T1
ATE502675T1 AT07822140T AT07822140T ATE502675T1 AT E502675 T1 ATE502675 T1 AT E502675T1 AT 07822140 T AT07822140 T AT 07822140T AT 07822140 T AT07822140 T AT 07822140T AT E502675 T1 ATE502675 T1 AT E502675T1
Authority
AT
Austria
Prior art keywords
compounds
strengthen
medicine
application
ampa receptor
Prior art date
Application number
AT07822140T
Other languages
German (de)
English (en)
Inventor
Daniel Bradley
Wai Chan
Kevin Thewlis
Simon Ward
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0621967A external-priority patent/GB0621967D0/en
Priority claimed from GB0717262A external-priority patent/GB0717262D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE502675T1 publication Critical patent/ATE502675T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
AT07822140T 2006-11-03 2007-11-01 Verbindungen, die den ampa-rezeptor verstärken, und deren anwendung in der medizin ATE502675T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0621967A GB0621967D0 (en) 2006-11-03 2006-11-03 Compounds
GB0717262A GB0717262D0 (en) 2007-09-05 2007-09-05 Compounds
PCT/EP2007/061794 WO2008053031A1 (en) 2006-11-03 2007-11-01 Compounds which potentiate ampa receptor and uses thereof in medicine

Publications (1)

Publication Number Publication Date
ATE502675T1 true ATE502675T1 (de) 2011-04-15

Family

ID=39099804

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07822140T ATE502675T1 (de) 2006-11-03 2007-11-01 Verbindungen, die den ampa-rezeptor verstärken, und deren anwendung in der medizin

Country Status (6)

Country Link
US (1) US20100137276A1 (enExample)
EP (1) EP2086643B1 (enExample)
JP (1) JP2010508328A (enExample)
AT (1) ATE502675T1 (enExample)
DE (1) DE602007013450D1 (enExample)
WO (1) WO2008053031A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0711089D0 (en) * 2007-06-08 2007-07-18 Glaxo Group Ltd Compounds
GB0711088D0 (en) * 2007-06-08 2007-07-18 Glaxo Group Ltd Compounds
WO2013118845A1 (ja) * 2012-02-08 2013-08-15 武田薬品工業株式会社 複素環化合物およびその用途
AU2016255434C1 (en) 2015-04-29 2021-09-23 Rapport Therapeutics, Inc. Azabenzimidazoles and their use as AMPA receptor modulators
BR112017023200A2 (pt) 2015-04-29 2018-08-07 Janssen Pharmaceutica Nv compostos de indolona e seu uso como moduladores do receptor de ampa
MX373652B (es) 2015-04-29 2020-04-02 Janssen Pharmaceutica Nv Imidazopirazinas y pirazolopirimidinas y su uso como moduladores del receptor de ampa.
WO2016176449A1 (en) 2015-04-29 2016-11-03 Janssen Pharmaceutica Nv Benzimidazolone and benzothiazolone compounds and their use as ampa receptor modulators
GB201702221D0 (en) * 2017-02-10 2017-03-29 Univ Of Sussex Compounds
GB201803340D0 (en) * 2018-03-01 2018-04-18 Univ Of Sussex Compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2159479B1 (es) 1999-10-25 2002-05-01 Menarini Lab Nuevos indazoles como inhibidores de la ciclooxigenasa-ii
ATE468326T1 (de) 2004-08-09 2010-06-15 Glaxo Group Ltd Verbindungen zur verstärkung der glutamatrezeptorwirkung und deren verwendung in der medizin

Also Published As

Publication number Publication date
JP2010508328A (ja) 2010-03-18
EP2086643A1 (en) 2009-08-12
WO2008053031A1 (en) 2008-05-08
US20100137276A1 (en) 2010-06-03
EP2086643B1 (en) 2011-03-23
DE602007013450D1 (de) 2011-05-05

Similar Documents

Publication Publication Date Title
ATE502675T1 (de) Verbindungen, die den ampa-rezeptor verstärken, und deren anwendung in der medizin
EA200802007A1 (ru) Соединения, потенцирующие рецептор амра, и применение указанных соединений в медицине
CY1119176T1 (el) 5-υποκατεστημενα παραγωγα κιναζολινονης ως αντικαρκινικοι παραγοντες
GB0612423D0 (en) Therapeutic agents
SE0402735D0 (sv) Novel compounds
MX393395B (es) Derivado de heteroaril[4,3-c]pirimidina-5-amina, método de preparación del mismo y usos médicos del mismo.
NZ595738A (en) Benzimidazole-piperidine-cyclohexane derivatives which have activity at M1 receptor and their uses in medicine
ATE556074T1 (de) Neue imidazoä1,5-aüpyridinderivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen, die diese enthalten
UY29384A1 (es) Derivados del ácido2-3s,4r)-4-(((3,4-dicloro-5-metil-1h-pirrol-2-il) carbonil)amino)-1,3-tiazol-5-carboxílico y sus sales, composiciones farmacéuticas que los contienen, procedimientos de preparación y aplicaciónes.
NZ612000A (en) Bicyclo[3.2.1]octyl amide derivatives and uses of same
BRPI0720551A2 (pt) composto ou um sal farmaceuticamente aceitável do mesmo, e, uso do mesmo, método para o tratamento de câncer, processos para a preparação de uma composição farmacêutica e de um composto ou de um sal farmaceuticamente aceitável do mesmo
UA96964C2 (ru) Соединения полициклической мочевины с антибактериальными свойствами
ATE360631T1 (de) Azabicyclische heterocyclen als modulatoren des cannabinoidrezeptors
WO2022261240A3 (en) Dimethoxyphenylalkylamine activators of serotonin receptors
UY28940A1 (es) Derivados de quinazolina
DE602005017895D1 (de) Pyrazolamid-derivate, diese verbindungen enthaltende zusammensetzungen und anwendungsverfahren
MY145647A (en) (4-hydroxy-2-oxo-3h-benzothiazol-7-yl)ethylamine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in therapy (for example in the treatment of respiratory disease states)
MX2010009022A (es) Derivados 16 alfa, 17 alfa-acetal glucocorticoesteroideos y su uso.
DE602008004540D1 (de) 2-oxo-2-(2-phenyl-5,6,7,8-tetrahydroindolizin-3-yl)acetamidderivate und verwandte verbindungen als antipilzmittel
MX2009013501A (es) Compuestos piperidinicos y sus usos.
ATE543804T1 (de) Neue verbindungen
ATE430744T1 (de) Thiazolylpiperidin-derivate nützlich als h3 rezeptor modulatoren
EA200801909A1 (ru) Соединения пиридина для лечения заболеваний, опосредованных действием простагландина
MX2010009756A (es) Agonistas de receptores muscarinicos, composiciones, metodos de tratamiento de los mismos, y proceso para preparacion de los mismos.
WO2007054257A3 (en) Indene derivatives, their preparation and use as medicaments

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties