ATE501728T1 - Therapeutische verwendung von lpi, einem inhibitor des lectinwegs in staphylokokken bei entzündungskrankheiten - Google Patents
Therapeutische verwendung von lpi, einem inhibitor des lectinwegs in staphylokokken bei entzündungskrankheitenInfo
- Publication number
- ATE501728T1 ATE501728T1 AT04740883T AT04740883T ATE501728T1 AT E501728 T1 ATE501728 T1 AT E501728T1 AT 04740883 T AT04740883 T AT 04740883T AT 04740883 T AT04740883 T AT 04740883T AT E501728 T1 ATE501728 T1 AT E501728T1
- Authority
- AT
- Austria
- Prior art keywords
- lpi
- poly
- activity
- lectin pathway
- peptides
- Prior art date
Links
- 102000004856 Lectins Human genes 0.000 title abstract 2
- 108090001090 Lectins Proteins 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 239000002523 lectin Substances 0.000 title abstract 2
- 230000037361 pathway Effects 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 230000000694 effects Effects 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 238000011282 treatment Methods 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03077138 | 2003-07-08 | ||
| PCT/EP2004/007606 WO2005005630A2 (en) | 2003-07-08 | 2004-07-08 | Therapeutic use of lpi, a staphylococcal lectin pathway inhibitor in inflammatory diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE501728T1 true ATE501728T1 (de) | 2011-04-15 |
Family
ID=34042904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04740883T ATE501728T1 (de) | 2003-07-08 | 2004-07-08 | Therapeutische verwendung von lpi, einem inhibitor des lectinwegs in staphylokokken bei entzündungskrankheiten |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20110118194A1 (de) |
| AT (1) | ATE501728T1 (de) |
| DE (1) | DE602004031836D1 (de) |
| DK (1) | DK1641926T3 (de) |
| ES (1) | ES2360399T3 (de) |
| WO (1) | WO2005005630A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090246175A1 (en) * | 2005-04-01 | 2009-10-01 | Umc Utrecht Holding B.V. | Therapeutic use of scin, a staphylococcal complement inhibitor in inflammatory diseases |
| US8524453B2 (en) | 2006-02-10 | 2013-09-03 | The Brigham And Woman's Hospital, Inc. | Lectin complement pathway assays and related compositions and methods |
| KR20220100997A (ko) * | 2012-06-18 | 2022-07-18 | 오메로스 코포레이션 | 다양한 질환 및 장애의 치료를 위해 masp-1 및/또는 masp-2 및/또는 masp-3를 억제하는 조성물 및 방법 |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11471497B1 (en) | 2019-03-13 | 2022-10-18 | David Gordon Bermudes | Copper chelation therapeutics |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4837193A (en) | 1992-09-21 | 1994-04-12 | Alfa-Laval Agri International Aktiebolag | Fibrinogen binding protein |
| US6737248B2 (en) * | 1996-01-05 | 2004-05-18 | Human Genome Sciences, Inc. | Staphylococcus aureus polynucleotides and sequences |
| NZ509051A (en) * | 1998-07-10 | 2003-01-31 | Jari Pharmaceuticals B | Chemotaxis-inhibiting protein of staphylococcus (CHIPS) and its use |
| GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| AU2004226262A1 (en) * | 2003-03-31 | 2004-10-14 | Intercell Ag | Staphylococcus epidermidis antigens |
| US20090202437A1 (en) * | 2003-07-08 | 2009-08-13 | Willem Jan Bastiaan Van Wamel | Therapeutic Use of Lpi, a Staphylococcal Lectin Pathway Inhibitor in Inflammatory diseases |
| US20090246175A1 (en) * | 2005-04-01 | 2009-10-01 | Umc Utrecht Holding B.V. | Therapeutic use of scin, a staphylococcal complement inhibitor in inflammatory diseases |
-
2004
- 2004-07-08 WO PCT/EP2004/007606 patent/WO2005005630A2/en active Application Filing
- 2004-07-08 ES ES04740883T patent/ES2360399T3/es not_active Expired - Lifetime
- 2004-07-08 DK DK04740883.6T patent/DK1641926T3/da active
- 2004-07-08 AT AT04740883T patent/ATE501728T1/de not_active IP Right Cessation
- 2004-07-08 DE DE602004031836T patent/DE602004031836D1/de not_active Expired - Lifetime
-
2010
- 2010-11-04 US US12/939,872 patent/US20110118194A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2360399T3 (es) | 2011-06-03 |
| WO2005005630A3 (en) | 2005-06-23 |
| DK1641926T3 (da) | 2011-06-27 |
| US20110118194A1 (en) | 2011-05-19 |
| WO2005005630A2 (en) | 2005-01-20 |
| DE602004031836D1 (de) | 2011-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |