ATE501710T1 - Somatostatin-analog-formulierungen - Google Patents
Somatostatin-analog-formulierungenInfo
- Publication number
- ATE501710T1 ATE501710T1 AT05818366T AT05818366T ATE501710T1 AT E501710 T1 ATE501710 T1 AT E501710T1 AT 05818366 T AT05818366 T AT 05818366T AT 05818366 T AT05818366 T AT 05818366T AT E501710 T1 ATE501710 T1 AT E501710T1
- Authority
- AT
- Austria
- Prior art keywords
- formulations
- somatostatin analog
- somatostatin
- administration
- analog formulations
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 8
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 abstract 5
- DEQANNDTNATYII-OULOTJBUSA-N (4r,7s,10s,13r,16s,19r)-10-(4-aminobutyl)-19-[[(2r)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-n-[(2r,3r)-1,3-dihydroxybutan-2-yl]-7-[(1r)-1-hydroxyethyl]-13-(1h-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxa Chemical compound C([C@@H](N)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC=2C3=CC=CC=C3NC=2)NC(=O)[C@H](CC=2C=CC=CC=2)NC1=O)C(=O)N[C@H](CO)[C@H](O)C)C1=CC=CC=C1 DEQANNDTNATYII-OULOTJBUSA-N 0.000 abstract 1
- 108010016076 Octreotide Proteins 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 150000001982 diacylglycerols Chemical class 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229960002700 octreotide Drugs 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0500807A GB0500807D0 (en) | 2005-01-14 | 2005-01-14 | Formulation |
| GB0507811A GB0507811D0 (en) | 2005-04-18 | 2005-04-18 | Formulation |
| PCT/GB2005/002217 WO2005117830A1 (en) | 2004-06-04 | 2005-06-06 | Liquid depot formulations |
| GB0518878A GB0518878D0 (en) | 2005-09-15 | 2005-09-15 | Formulations |
| PCT/GB2005/004748 WO2006075124A1 (en) | 2005-01-14 | 2005-12-09 | Somatostatin analogue formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE501710T1 true ATE501710T1 (de) | 2011-04-15 |
Family
ID=40432504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05818366T ATE501710T1 (de) | 2005-01-14 | 2005-12-09 | Somatostatin-analog-formulierungen |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US8871712B2 (de) |
| AT (1) | ATE501710T1 (de) |
| DE (1) | DE602005026998D1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9649382B2 (en) | 2005-01-14 | 2017-05-16 | Camurus Ab | Topical bioadhesive formulations |
| SI1845942T1 (sl) | 2005-01-14 | 2014-06-30 | Camurus Ab | Gnrh analogne formulacije |
| KR101245022B1 (ko) * | 2005-01-21 | 2013-03-19 | 카무러스 에이비 | 약제학적 지질 조성물 |
| DK1888031T3 (da) * | 2005-06-06 | 2013-02-18 | Camurus Ab | GLP-1-analogformuleringer |
| GB0711656D0 (en) * | 2007-06-15 | 2007-07-25 | Camurus Ab | Formulations |
| GB0716385D0 (en) | 2007-08-22 | 2007-10-03 | Camurus Ab | Formulations |
| GB0815435D0 (en) | 2008-08-22 | 2008-10-01 | Camurus Ab | Formulations |
| ES2834318T3 (es) | 2012-05-25 | 2021-06-17 | Camurus Ab | Formulaciones de agonistas de receptores de la somatostatina |
| AU2017336199B2 (en) * | 2016-09-27 | 2020-08-20 | Camurus Ab | Mixtures and formulations comprising an alkyl ammonium EDTA salt |
| WO2018067987A1 (en) * | 2016-10-06 | 2018-04-12 | Amgen Inc. | Reduced viscosity protein pharmaceutical formulations |
| EP3551210A1 (de) | 2016-12-07 | 2019-10-16 | RA Pharmaceuticals, Inc. | Modulatoren der komplementaktivität |
| CN113368041B (zh) * | 2020-07-17 | 2023-01-03 | 丽珠医药集团股份有限公司 | 药物组合物、缓释制剂及其制备方法 |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US595502A (en) * | 1897-12-14 | terpeningt | ||
| GB2209937B (en) * | 1987-09-21 | 1991-07-03 | Depiopharm S A | Water insoluble polypeptides |
| US4938763B1 (en) * | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
| US5340802A (en) * | 1989-06-30 | 1994-08-23 | Abbott Laboratories | Peptide analog type-B CCK receptor ligands |
| PH30995A (en) * | 1989-07-07 | 1997-12-23 | Novartis Inc | Sustained release formulations of water soluble peptides. |
| MY107937A (en) * | 1990-02-13 | 1996-06-29 | Takeda Chemical Industries Ltd | Prolonged release microcapsules. |
| WO1993006921A1 (en) | 1991-10-04 | 1993-04-15 | Gs Biochem Ab | Particles, method of preparing said particles and uses thereof |
| EP0643620B1 (de) * | 1991-10-04 | 1999-07-21 | Gs Development Ab | Teilchen, methode zur herstellung der teilchen und deren verwendung |
| US6228383B1 (en) * | 1994-03-03 | 2001-05-08 | Gs Development Ab | Use of fatty acid esters as bioadhesive substances |
| ES2135723T3 (es) | 1994-03-30 | 1999-11-01 | Gs Dev Ab | Uso de esteres de acidos grasos como sustancias bioadhesivas. |
| SE518578C2 (sv) | 1994-06-15 | 2002-10-29 | Gs Dev Ab | Lipidbaserad komposition |
| FR2725369B1 (fr) * | 1994-10-07 | 1997-01-03 | Oreal | Composition cosmetique ou dermatologique constituee d'une emulsion huile dans eau a base de globules huileux pourvus d'un enrobage cristal liquide lamellaire |
| JPH11513393A (ja) | 1995-10-12 | 1999-11-16 | ジーエス ディベロップメント エービー | 皮膚又は粘膜表面へのもしくは介する活性物質の投与用医薬組成物 |
| US6458924B2 (en) * | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| EP0839525B1 (de) * | 1996-10-31 | 2004-08-04 | Takeda Chemical Industries, Ltd. | Zubereitung mit verzögerter Freisetzung |
| CA2286052A1 (en) | 1997-04-17 | 1998-10-29 | Lise Sylvest Nielsen | A novel bioadhesive drug delivery system based on liquid crystals |
| US6638621B2 (en) * | 2000-08-16 | 2003-10-28 | Lyotropic Therapeutics, Inc. | Coated particles, methods of making and using |
| US20040018241A1 (en) * | 1997-09-26 | 2004-01-29 | Noven Pharmaceuticals, Inc. | Bioadhesive compositions and methods for topical administration of active agents |
| US6320017B1 (en) * | 1997-12-23 | 2001-11-20 | Inex Pharmaceuticals Corp. | Polyamide oligomers |
| BE1011899A6 (fr) * | 1998-04-30 | 2000-02-01 | Ucb Sa | Compositions pharmaceutiques gelifiables utilisables. |
| SI1140148T1 (sl) | 1998-12-22 | 2006-04-30 | Lilly Co Eli | Stabilna formulacija raztopine glukagonu podobnega peptida-1 |
| US20020153508A1 (en) | 2000-06-29 | 2002-10-24 | Lynch Matthew Lawrence | Cubic liquid crystalline compositions and methods for their preparation |
| US7008646B2 (en) | 2001-02-20 | 2006-03-07 | Patrick Thomas Spicer | Cubic liquid crystalline compositions and methods for their preparation |
| US6936187B2 (en) | 2001-02-21 | 2005-08-30 | Matthew Lawrence Lynch | Functionalized cubic liquid crystalline phase materials and methods for their preparation and use |
| US6656385B2 (en) | 2001-02-21 | 2003-12-02 | The Procter & Gamble Company | Functionalized cubic liquid crystalline phase materials and methods for their preparation and use |
| EP1408932A4 (de) * | 2001-06-23 | 2009-02-25 | Lyotropic Therapeutics Inc | Teilchen mit verbesserter solubilisierungseigenschaft |
| EP1412384B1 (de) | 2001-06-28 | 2007-12-26 | Novo Nordisk A/S | Stabile formulierung von modifiziertem glp-1 |
| CA2472882A1 (en) | 2002-01-10 | 2003-07-17 | Imperial College Innovations Ltd | Use of pyy and glp-1, or an agonist thereof, for the modification of feeding behaviour |
| US7622118B2 (en) * | 2002-07-15 | 2009-11-24 | Board Of Regents, The University Of Texas System | Cancer treatment methods using selected antibodies to aminophospholipids |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| GB0305941D0 (en) * | 2003-03-14 | 2003-04-23 | Camurus Ab | Composition |
| GB0307777D0 (en) | 2003-04-04 | 2003-05-07 | Medical Res Council | Conjugate compounds |
| JP2007501213A (ja) * | 2003-08-04 | 2007-01-25 | カムルス エービー | 両親媒性粒子に活性因子を装填する方法 |
| WO2005021022A2 (en) | 2003-09-01 | 2005-03-10 | Novo Nordisk A/S | Stable formulations of peptides |
| GB0322033D0 (en) * | 2003-09-19 | 2003-10-22 | Camurus Ab | Composition |
| AU2005324794C1 (en) | 2003-11-07 | 2010-12-02 | Camurus Ab | Somatostatin analogue formulations |
| EP1682091B1 (de) * | 2003-11-07 | 2017-03-29 | Camurus Ab | Zusammensetzungen von lipiden und kationischen peptiden |
| WO2005063213A1 (en) | 2003-12-19 | 2005-07-14 | Biodelivery Sciences International, Inc. | Rigid liposomal cochleate and methods of use and manufacture |
| CA2554052C (en) | 2004-01-23 | 2013-10-22 | Camurus Ab | Ternary non-lamellar lipid compositions of structure forming amphiphile, structure swelling amphiphile and dispersion stabilising amphiphile |
| GB0401513D0 (en) * | 2004-01-23 | 2004-02-25 | Camurus Ab | Compositions |
| ATE401054T1 (de) * | 2004-06-04 | 2008-08-15 | Camurus Ab | Flüssige depotformulierungen |
| EP1778187B1 (de) * | 2004-08-04 | 2012-05-23 | Camurus Ab | Nichtlamellare dispersionen bildende zusammensetzungen |
| SI1845942T1 (sl) * | 2005-01-14 | 2014-06-30 | Camurus Ab | Gnrh analogne formulacije |
| EP1848403B8 (de) | 2005-01-14 | 2010-05-19 | Camurus Ab | Topische bioadhäsive formulierungen |
| KR101245022B1 (ko) * | 2005-01-21 | 2013-03-19 | 카무러스 에이비 | 약제학적 지질 조성물 |
| DK1888031T3 (da) * | 2005-06-06 | 2013-02-18 | Camurus Ab | GLP-1-analogformuleringer |
| CN103071209A (zh) * | 2005-11-17 | 2013-05-01 | 周吉尼克斯股份有限公司 | 用无针注射递送粘稠制剂 |
| GB0711656D0 (en) | 2007-06-15 | 2007-07-25 | Camurus Ab | Formulations |
| GB0716385D0 (en) * | 2007-08-22 | 2007-10-03 | Camurus Ab | Formulations |
| GB0815435D0 (en) * | 2008-08-22 | 2008-10-01 | Camurus Ab | Formulations |
-
2005
- 2005-12-09 US US11/795,249 patent/US8871712B2/en active Active
- 2005-12-09 DE DE602005026998T patent/DE602005026998D1/de not_active Expired - Lifetime
- 2005-12-09 AT AT05818366T patent/ATE501710T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005026998D1 (de) | 2011-04-28 |
| US8871712B2 (en) | 2014-10-28 |
| US20090069221A1 (en) | 2009-03-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |