ATE501271T1 - Verfahren und vorrichtung zur gleichzeitigen quantifizierung verschiedener radionuklide auf der oberfläche eines biologischen mikroarrays - Google Patents

Verfahren und vorrichtung zur gleichzeitigen quantifizierung verschiedener radionuklide auf der oberfläche eines biologischen mikroarrays

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Publication number
ATE501271T1
ATE501271T1 AT02716498T AT02716498T ATE501271T1 AT E501271 T1 ATE501271 T1 AT E501271T1 AT 02716498 T AT02716498 T AT 02716498T AT 02716498 T AT02716498 T AT 02716498T AT E501271 T1 ATE501271 T1 AT E501271T1
Authority
AT
Austria
Prior art keywords
simultaneous quantification
nuclides
different radionuclides
biological microarray
radioactive nuclides
Prior art date
Application number
AT02716498T
Other languages
English (en)
Inventor
Eivind Hovig
Arne Skretting
Einar Nygard
Yngve Kvinnsland
Knut Breistol
Koki Yoshioka
Original Assignee
Biomolex As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomolex As filed Critical Biomolex As
Application granted granted Critical
Publication of ATE501271T1 publication Critical patent/ATE501271T1/de

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845Methods of identifying protein-protein interactions in protein mixtures

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measurement Of Radiation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT02716498T 2001-01-12 2002-01-11 Verfahren und vorrichtung zur gleichzeitigen quantifizierung verschiedener radionuklide auf der oberfläche eines biologischen mikroarrays ATE501271T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20010229A NO316478B1 (no) 2001-01-12 2001-01-12 Fremgangsmåte og apparat for simultan kvantifisering av ulike radionuklideri et stort antall regioner på overflaten av en biologiskmikromatrise eller lignende objekt
PCT/NO2002/000014 WO2002059365A1 (en) 2001-01-12 2002-01-11 Method and apparatus for simultaneous quantification of different radionuclides on the surface of a biological microarray

Publications (1)

Publication Number Publication Date
ATE501271T1 true ATE501271T1 (de) 2011-03-15

Family

ID=19912004

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02716498T ATE501271T1 (de) 2001-01-12 2002-01-11 Verfahren und vorrichtung zur gleichzeitigen quantifizierung verschiedener radionuklide auf der oberfläche eines biologischen mikroarrays

Country Status (10)

Country Link
EP (1) EP1358357B1 (de)
JP (1) JP2004523233A (de)
KR (1) KR20030066810A (de)
CN (1) CN1496411A (de)
AT (1) ATE501271T1 (de)
CA (1) CA2434093A1 (de)
DE (1) DE60239388D1 (de)
EA (1) EA006014B1 (de)
NO (1) NO316478B1 (de)
WO (1) WO2002059365A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1689882B1 (de) * 2003-10-07 2014-11-26 TRAN, Nathaniel Tue Radioaktive multiplex-analyseverfahren
DE102008017716A1 (de) 2008-04-07 2009-10-08 Volkswagen Ag Anzeige- und Bedienvorrichtung für ein Kraftfahrzeug sowie Verfahren zum Betreiben einer solchen
GB201303830D0 (en) * 2013-03-04 2013-04-17 Univ Glasgow Methods,unit and device relating to the manufacture,processing,synthesising or screening of radiopharmaceutical compositions
CA2948699C (en) 2014-05-13 2019-11-26 Paul Scherrer Institut Production of 43sc radionuclide and radiopharmaceuticals thereof for use in positron emission tomography
CN104965014B (zh) * 2015-07-06 2017-06-23 济南大学 用于检测sam的量子点/酶复合碳糊电极的制备方法
WO2024091986A1 (en) * 2022-10-28 2024-05-02 President And Fellows Of Harvard College Electrochemical systems with massively parallel array of controllable electrochemical cells and sensor system for sparse sensing
CN117452469B (zh) * 2023-12-26 2024-03-19 山东大学 一种细胞内辐射微剂量探测结构及探测方法
CN119833197B (zh) * 2025-01-07 2025-08-12 中国人民解放军总医院第八医学中心 一种用于放射性废液的智能处理系统

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8626575D0 (en) * 1986-11-06 1986-12-10 Amersham Int Plc Biochemical sequencing
US4967084A (en) * 1989-02-02 1990-10-30 The University Of Michigan Multi-sample scintillation counter using position-sensitive detector
US5117114A (en) * 1989-12-11 1992-05-26 The Regents Of The University Of California High resolution amorphous silicon radiation detectors
NO930164L (no) 1993-01-18 1994-07-19 Integrert Detektor Og Elektron Elektronisk strålingsavbildningssystem
US5532122A (en) * 1993-10-12 1996-07-02 Biotraces, Inc. Quantitation of gamma and x-ray emitting isotopes
EP0853427B1 (de) * 1994-06-01 2008-10-15 Ipl Intellectual Property Licensing Limited Vorrichtungen, Systeme und Methoden zur Aufnahme von Bildern
GB2311198B (en) 1996-03-14 1998-05-06 Simage Oy Autoradiography imaging
US5960349A (en) 1997-05-20 1999-09-28 Northern Telecom Enhanced cellular layout for CDMA networks having six-sectored cells
WO1999008233A1 (en) * 1997-08-07 1999-02-18 Imaging Research Inc. A digital imaging system for assays in well plates, gels and blots

Also Published As

Publication number Publication date
WO2002059365A1 (en) 2002-08-01
EP1358357B1 (de) 2011-03-09
EA200300785A1 (ru) 2003-12-25
NO20010229D0 (no) 2001-01-12
NO316478B1 (no) 2004-01-26
NO20010229L (no) 2002-07-15
JP2004523233A (ja) 2004-08-05
CA2434093A1 (en) 2002-08-01
DE60239388D1 (de) 2011-04-21
KR20030066810A (ko) 2003-08-09
EA006014B1 (ru) 2005-08-25
CN1496411A (zh) 2004-05-12
WO2002059365A8 (en) 2003-12-11
EP1358357A1 (de) 2003-11-05

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