ATE495734T1 - Formulierungen von organischen platinverbindungen in anwesenheit von assoziativen polymeren, so erhaltene produkte und ihre anwendungen - Google Patents
Formulierungen von organischen platinverbindungen in anwesenheit von assoziativen polymeren, so erhaltene produkte und ihre anwendungenInfo
- Publication number
- ATE495734T1 ATE495734T1 AT08840675T AT08840675T ATE495734T1 AT E495734 T1 ATE495734 T1 AT E495734T1 AT 08840675 T AT08840675 T AT 08840675T AT 08840675 T AT08840675 T AT 08840675T AT E495734 T1 ATE495734 T1 AT E495734T1
- Authority
- AT
- Austria
- Prior art keywords
- formulations
- products
- applications
- platinum compounds
- associative polymers
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 229940045985 antineoplastic platinum compound Drugs 0.000 title 1
- 150000003058 platinum compounds Chemical class 0.000 title 1
- 229920000642 polymer Polymers 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 3
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 2
- 238000009096 combination chemotherapy Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 229920003169 water-soluble polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
- C08F290/06—Polymers provided for in subclass C08G
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
- C08F290/06—Polymers provided for in subclass C08G
- C08F290/061—Polyesters; Polycarbonates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
- C08F290/06—Polymers provided for in subclass C08G
- C08F290/062—Polyethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0707306A FR2922452B1 (fr) | 2007-10-19 | 2007-10-19 | Formulations de composes organoplatiniques en presence de polymeres associatifs, produits obtenus et leurs utilisations |
| PCT/IB2008/002669 WO2009050555A2 (fr) | 2007-10-19 | 2008-10-07 | Formulations de composes organoplatiniques en presence de polymeres associatifs, produits obtenus et leurs utilisations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE495734T1 true ATE495734T1 (de) | 2011-02-15 |
Family
ID=39431012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08840675T ATE495734T1 (de) | 2007-10-19 | 2008-10-07 | Formulierungen von organischen platinverbindungen in anwesenheit von assoziativen polymeren, so erhaltene produkte und ihre anwendungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20100278925A1 (de) |
| EP (1) | EP2231131B1 (de) |
| JP (1) | JP2011500660A (de) |
| CN (1) | CN101827587A (de) |
| AT (1) | ATE495734T1 (de) |
| DE (1) | DE602008004675D1 (de) |
| DK (1) | DK2231131T3 (de) |
| ES (1) | ES2362559T3 (de) |
| FR (1) | FR2922452B1 (de) |
| IL (1) | IL204427A (de) |
| WO (1) | WO2009050555A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA116535C2 (uk) | 2012-03-30 | 2018-04-10 | Рдінновейшн Апс | Сполуки бензолполікарбонових кислот та їх застосування як лікарських засобів |
| FR3107667A1 (fr) | 2020-02-27 | 2021-09-03 | Melchior Material And Life Science France | Doses unitaires pour la liberation d’une formulation aqueuse |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US290969A (en) * | 1883-12-25 | Device for handling spooled barbed wire | ||
| US277108A (en) * | 1883-05-08 | Clamp for sewing-machine attachments | ||
| US361505A (en) * | 1887-04-19 | Folding portable tent | ||
| US257621A (en) * | 1882-05-09 | And chaeles e | ||
| US277116A (en) * | 1883-05-08 | Daniel conboy | ||
| US312876A (en) * | 1885-02-24 | Saloon-hopper tube for keeping clean saloon-hoppers in railroad-cars | ||
| US255323A (en) * | 1882-03-21 | Israel e | ||
| US257622A (en) * | 1882-05-09 | John w | ||
| US277118A (en) * | 1883-05-08 | Apparatus for operating railway-signals | ||
| US255326A (en) * | 1882-03-21 | ordway | ||
| US312848A (en) * | 1885-02-24 | Watch | ||
| US255325A (en) * | 1882-03-21 | Oastler | ||
| US277113A (en) * | 1883-05-08 | Air-gas machine | ||
| US361629A (en) * | 1887-04-19 | Friction-clutch pulley | ||
| US257623A (en) * | 1882-05-09 | John m | ||
| US312834A (en) * | 1885-02-24 | Device for milking cows | ||
| US324919A (en) * | 1885-08-25 | Liniment | ||
| US277120A (en) * | 1883-05-08 | Island | ||
| US290983A (en) * | 1883-12-25 | bbanson | ||
| US284544A (en) * | 1883-09-04 | Othniel b | ||
| US361643A (en) * | 1887-04-19 | William phillips | ||
| US290955A (en) * | 1883-12-25 | Half to charles green | ||
| US273996A (en) * | 1883-03-13 | Oheistopher hymees | ||
| US361615A (en) * | 1887-04-19 | Chair | ||
| US312820A (en) * | 1885-02-24 | Barb-fence machine | ||
| US356004A (en) * | 1887-01-11 | Combined wood | ||
| FR2633930B1 (fr) * | 1988-07-07 | 1991-04-19 | Coatex Sa | Agent epaississant modificateur des caracteristiques rheologiques de compositions aqueuses chargees et/ou pigmentees, blanches ou colorees |
| EP0706376B2 (de) * | 1993-07-19 | 2007-08-08 | Angiotech Pharmaceuticals, Inc. | Anti-angiogene mittel und verfahren zu deren verwendung |
| US20030203976A1 (en) * | 1993-07-19 | 2003-10-30 | William L. Hunter | Anti-angiogenic compositions and methods of use |
| US6004573A (en) * | 1997-10-03 | 1999-12-21 | Macromed, Inc. | Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
| US6861397B2 (en) * | 1999-06-23 | 2005-03-01 | The Dial Corporation | Compositions having enhanced deposition of a topically active compound on a surface |
| AU2001292235A1 (en) * | 2000-09-26 | 2002-04-08 | Center For Advanced Science And Technology Incubation, Ltd. | Polymeric micelle containing cisplatin enclosed therein and use thereof |
| US7094810B2 (en) * | 2001-06-08 | 2006-08-22 | Labopharm, Inc. | pH-sensitive block copolymers for pharmaceutical compositions |
| WO2003037383A1 (en) * | 2001-10-29 | 2003-05-08 | The Dow Chemical Company | An antineoplastic- dendritic polymer drug delivery system |
| FR2846978B1 (fr) * | 2002-11-08 | 2007-05-18 | Coatex Sas | Utilisation d'un copolymere disposant d'au moins une fonction greffee alkoxy ou hydroxy polyalkylene glycol, comme agent ameliorant l'activation de l'azurage optique et produits obtenus |
| US7682630B2 (en) * | 2003-05-26 | 2010-03-23 | Hiroshi Maeda | Antitumor agent and process for producing the same |
| JP2007508243A (ja) * | 2003-08-04 | 2007-04-05 | フォーミックス エルティーディー． | 両親媒性コポリマーゲル化剤を含む泡坦体 |
-
2007
- 2007-10-19 FR FR0707306A patent/FR2922452B1/fr not_active Expired - Fee Related
-
2008
- 2008-10-07 JP JP2010529465A patent/JP2011500660A/ja not_active Withdrawn
- 2008-10-07 US US12/738,302 patent/US20100278925A1/en not_active Abandoned
- 2008-10-07 AT AT08840675T patent/ATE495734T1/de active
- 2008-10-07 DE DE602008004675T patent/DE602008004675D1/de active Active
- 2008-10-07 WO PCT/IB2008/002669 patent/WO2009050555A2/fr active Application Filing
- 2008-10-07 DK DK08840675.6T patent/DK2231131T3/da active
- 2008-10-07 CN CN200880112050A patent/CN101827587A/zh active Pending
- 2008-10-07 EP EP08840675A patent/EP2231131B1/de active Active
- 2008-10-07 ES ES08840675T patent/ES2362559T3/es active Active
-
2010
- 2010-03-11 IL IL204427A patent/IL204427A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| IL204427A (en) | 2013-10-31 |
| JP2011500660A (ja) | 2011-01-06 |
| EP2231131A2 (de) | 2010-09-29 |
| FR2922452A1 (fr) | 2009-04-24 |
| US20100278925A1 (en) | 2010-11-04 |
| FR2922452B1 (fr) | 2010-01-22 |
| ES2362559T3 (es) | 2011-07-07 |
| WO2009050555A3 (fr) | 2009-06-04 |
| EP2231131B1 (de) | 2011-01-19 |
| DK2231131T3 (da) | 2011-04-26 |
| WO2009050555A2 (fr) | 2009-04-23 |
| CN101827587A (zh) | 2010-09-08 |
| DE602008004675D1 (de) | 2011-03-03 |
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| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification |
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