ATE495239T1 - Zellen für adenovirusvektor- und proteinherstellung - Google Patents
Zellen für adenovirusvektor- und proteinherstellungInfo
- Publication number
- ATE495239T1 ATE495239T1 AT08743728T AT08743728T ATE495239T1 AT E495239 T1 ATE495239 T1 AT E495239T1 AT 08743728 T AT08743728 T AT 08743728T AT 08743728 T AT08743728 T AT 08743728T AT E495239 T1 ATE495239 T1 AT E495239T1
- Authority
- AT
- Austria
- Prior art keywords
- protein production
- cells
- adenovirus vector
- line
- adenovirus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0091—Purification or manufacturing processes for gene therapy compositions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0684—Cells of the urinary tract or kidneys
- C12N5/0686—Kidney cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10351—Methods of production or purification of viral material
- C12N2710/10352—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Plant Pathology (AREA)
- Manufacturing & Machinery (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89401807P | 2007-03-09 | 2007-03-09 | |
PCT/US2008/056198 WO2008112540A2 (en) | 2007-03-09 | 2008-03-07 | Cells for adenovirus vector and protein production |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE495239T1 true ATE495239T1 (de) | 2011-01-15 |
Family
ID=39743143
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08743728T ATE495239T1 (de) | 2007-03-09 | 2008-03-07 | Zellen für adenovirusvektor- und proteinherstellung |
Country Status (5)
Country | Link |
---|---|
US (1) | US20090227031A1 (de) |
EP (1) | EP2132300B1 (de) |
AT (1) | ATE495239T1 (de) |
DE (1) | DE602008004476D1 (de) |
WO (1) | WO2008112540A2 (de) |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5464764A (en) * | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
EP0911413A3 (de) * | 1992-12-03 | 2000-11-15 | Genzyme Corporation | Mindestadenovirus-Vector zur Gentherapie |
US6004941A (en) * | 1993-06-14 | 1999-12-21 | Basf Aktiengesellschaft | Methods for regulating gene expression |
EP0784690B1 (de) * | 1994-06-10 | 2006-08-16 | Genvec, Inc. | Adenoviren-vektor systeme und zelllinien |
US5851806A (en) * | 1994-06-10 | 1998-12-22 | Genvec, Inc. | Complementary adenoviral systems and cell lines |
US6265212B1 (en) * | 1995-06-15 | 2001-07-24 | Introgene B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
US6783980B2 (en) * | 1995-06-15 | 2004-08-31 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
EP0833934B2 (de) * | 1995-06-15 | 2012-08-15 | Crucell Holland B.V. | Verpackungssysteme für humane, menschliche adenoviren, zur verwendung in die gentherapie |
US5972650A (en) * | 1997-06-26 | 1999-10-26 | Brigham And Women's Hospital | Tetracycline repressor regulated mammalian cell transcription and viral replication switch |
US6989264B2 (en) * | 1997-09-05 | 2006-01-24 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
WO1999041398A1 (en) * | 1998-02-11 | 1999-08-19 | Genvec, Inc. | Vectors, cells and methods for the production of deleterious viral eukaryotic gene transfer vectors |
US6670188B1 (en) * | 1998-04-24 | 2003-12-30 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
WO1999057296A1 (en) * | 1998-05-01 | 1999-11-11 | Genzyme Corporation | Partially deleted adenoviral vectors |
US6291214B1 (en) * | 1998-05-11 | 2001-09-18 | Glaxo Wellcome Inc. | System for generating recombinant viruses |
US6855544B1 (en) * | 1999-04-15 | 2005-02-15 | Crucell Holland B.V. | Recombinant protein production in a human cell |
US6913922B1 (en) * | 1999-05-18 | 2005-07-05 | Crucell Holland B.V. | Serotype of adenovirus and uses thereof |
US6492169B1 (en) * | 1999-05-18 | 2002-12-10 | Crucell Holland, B.V. | Complementing cell lines |
WO2000072887A1 (en) * | 1999-05-28 | 2000-12-07 | Mount Sinai School Of Medicine | A novel packaging cell line for the rescue, production and titration of high-capacity adenovirus amplicon vectors |
US6541245B1 (en) * | 1999-09-23 | 2003-04-01 | Genzyme Corporation | Adenoviral helper vectors |
US6579522B1 (en) * | 2000-06-27 | 2003-06-17 | Genvec, Inc. | Replication deficient adenoviral TNF vector |
US6682929B2 (en) * | 2001-07-23 | 2004-01-27 | Genvec, Inc. | Adenovector complementing cells |
US6677156B2 (en) * | 2001-07-23 | 2004-01-13 | Genvec, Inc. | Non-adenoviral gene product-based complementing cells for adenoviral vectors |
CA2454992A1 (en) * | 2001-09-13 | 2003-03-20 | Genvec, Inc. | Adenoviral vector and related system and methods of making and use |
DK1463751T3 (da) * | 2001-12-21 | 2013-08-26 | Human Genome Sciences Inc | Albuminfusionsproteiner. |
US7189561B2 (en) * | 2004-09-21 | 2007-03-13 | Advec, Inc. | Production of adenovirus vectors with reduced levels of replication competent adenovirus contamination |
-
2008
- 2008-03-07 WO PCT/US2008/056198 patent/WO2008112540A2/en active Application Filing
- 2008-03-07 DE DE602008004476T patent/DE602008004476D1/de active Active
- 2008-03-07 US US12/044,423 patent/US20090227031A1/en not_active Abandoned
- 2008-03-07 EP EP08743728A patent/EP2132300B1/de not_active Not-in-force
- 2008-03-07 AT AT08743728T patent/ATE495239T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE602008004476D1 (de) | 2011-02-24 |
WO2008112540A3 (en) | 2008-12-04 |
US20090227031A1 (en) | 2009-09-10 |
WO2008112540A2 (en) | 2008-09-18 |
EP2132300A2 (de) | 2009-12-16 |
EP2132300B1 (de) | 2011-01-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1948789T3 (da) | Fremgangsmåde til fremstilling af permanente, humane cellelinjer | |
EA200901388A1 (ru) | Повышение продуктивности растений путем комбинирования химических веществ с трансгенными модификациями | |
TR201903707T4 (tr) | Aşırı yükleme ve elüsyon kromatografisi. | |
MX2019004378A (es) | Edulcorante de estevia altamente soluble. | |
DE602005024180D1 (de) | Erzeugungssystem für brennstoffzellen des polymer-elektrolyttyps | |
UY34374A (es) | Benzilindazoles sustituidos | |
DK3421597T3 (da) | System til chrysosporium lucknowense-proteinfremstilling | |
PA8676401A1 (es) | Metodos para purificar tigeciclina | |
UA115022C2 (uk) | Трансгенна рослина, яка містить нуклеїнову кислоту, що має виділену нуклеотидну послідовність, яка кодує модифіковану інтеїном ксиланазу | |
EP2516624A4 (de) | Zelllinie 3m | |
MY152682A (en) | Swollenin compositions and methods of increasing the efficency of a cellulase | |
MA32827B1 (fr) | Procede de sequestration de carbone | |
RS54073B1 (en) | STROMAL MATERIAL CELLS | |
EA201300876A1 (ru) | Мутантная целлобиогидролаза | |
CY1118539T1 (el) | Ανασυνδυασμενο μυκοβακτηριο ως εμβολιο | |
ATE490354T1 (de) | Elektrode für membranelektrolysezellen | |
UA115235C2 (uk) | Ген токсину axmi335 bacillus thuringiensis та спосіб його застосування | |
BR112014011943A2 (pt) | plantas tolerantes à seca produzidas por modificação do locus stgx estadia-verde | |
CY1124624T1 (el) | Μητρες οι οποιες περιεχουν εναν τροποποιημενο πολυσακχαριτη | |
CL2013000893A1 (es) | Medio para cultivo de celulas de mamiferos que comprende sobrenadante de la etapa i del fraccionamiento de cohn; procedimiento de preparacion del medio; uso del medio de cultivo para cultivar celulas de mamiferos. | |
MX2022000516A (es) | Metodos relacionados con celulas pluripotentes. | |
EA201171278A1 (ru) | Отвечающая за засуху экпрессия генов с промотора rab17 zea mays | |
BR112012029188A2 (pt) | clareadores óticos e composições compreendendo os mesmos | |
ATE495239T1 (de) | Zellen für adenovirusvektor- und proteinherstellung | |
WO2012175745A9 (en) | Cell secreted proteins for the treatment of myocardial infarction |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |