ATE490343T1 - Nachweisverfahren für die genexpression - Google Patents
Nachweisverfahren für die genexpressionInfo
- Publication number
- ATE490343T1 ATE490343T1 AT06774225T AT06774225T ATE490343T1 AT E490343 T1 ATE490343 T1 AT E490343T1 AT 06774225 T AT06774225 T AT 06774225T AT 06774225 T AT06774225 T AT 06774225T AT E490343 T1 ATE490343 T1 AT E490343T1
- Authority
- AT
- Austria
- Prior art keywords
- hybridization
- oligonucleotide probes
- gene expression
- genes
- approach
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title 1
- 230000014509 gene expression Effects 0.000 title 1
- 108020005187 Oligonucleotide Probes Proteins 0.000 abstract 3
- 238000009396 hybridization Methods 0.000 abstract 3
- 239000002751 oligonucleotide probe Substances 0.000 abstract 3
- 108091034117 Oligonucleotide Proteins 0.000 abstract 2
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000000523 sample Substances 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 238000003491 array Methods 0.000 abstract 1
- 239000011324 bead Substances 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000011223 gene expression profiling Methods 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69554905P | 2005-06-30 | 2005-06-30 | |
| PCT/US2006/025233 WO2007005482A1 (en) | 2005-06-30 | 2006-06-28 | Detection method for gene expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE490343T1 true ATE490343T1 (de) | 2010-12-15 |
Family
ID=37432262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06774225T ATE490343T1 (de) | 2005-06-30 | 2006-06-28 | Nachweisverfahren für die genexpression |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7914983B2 (de) |
| EP (1) | EP1913159B1 (de) |
| JP (1) | JP5058160B2 (de) |
| AT (1) | ATE490343T1 (de) |
| DE (1) | DE602006018622D1 (de) |
| WO (1) | WO2007005482A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2744916A4 (de) | 2011-07-13 | 2015-06-17 | Primeradx Inc | Multimodale verfahren zur simultanen erkennung und quantifizierung mehrerer nukleinsäuren in einer probe |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US115590A (en) * | 1871-06-06 | Lfxlproxeixie | ||
| DE2916711A1 (de) * | 1979-04-25 | 1980-11-06 | Behringwerke Ag | Blutgerinnungsfaktoren und verfahren zu ihrer herstellung |
| US4956386A (en) * | 1980-04-25 | 1990-09-11 | Gist-Brocades N.V. | Pharmaceutical compositions and process for their preparation |
| US5665544A (en) * | 1992-05-27 | 1997-09-09 | Amersham International Plc | RNA fingerprinting to determine RNA population differences |
| US5576291A (en) * | 1993-09-13 | 1996-11-19 | Baxter International Inc. | Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency |
| US5649959A (en) * | 1995-02-10 | 1997-07-22 | Sherwood Medical Company | Assembly for sealing a puncture in a vessel |
| US7282327B2 (en) * | 1996-01-23 | 2007-10-16 | Affymetrix, Inc. | Nucleic acid labeling compounds |
| US5770700A (en) * | 1996-01-25 | 1998-06-23 | Genetics Institute, Inc. | Liquid factor IX formulations |
| WO1997045559A1 (en) * | 1996-05-29 | 1997-12-04 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions |
| ATE273381T1 (de) * | 1997-02-12 | 2004-08-15 | Eugene Y Chan | Verfahren zur analyse von polymeren |
| US6004755A (en) * | 1998-04-07 | 1999-12-21 | Incyte Pharmaceuticals, Inc. | Quantitative microarray hybridizaton assays |
| US20040054162A1 (en) * | 2001-10-30 | 2004-03-18 | Hanna Michelle M. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
| DE60235491D1 (de) * | 2001-11-28 | 2010-04-08 | Bio Rad Laboratories | Paralleles scoring von polymorphismen mittels amplifikation und fehlerkorrektur |
| CA2500129C (en) * | 2002-09-30 | 2011-03-29 | F. Hoffmann-La Roche Ag | Oligonucleotides for genotyping thymidylate synthase gene |
| US7354706B2 (en) * | 2003-09-09 | 2008-04-08 | The Regents Of The University Of Colorado, A Body Corporate | Use of photopolymerization for amplification and detection of a molecular recognition event |
| EP1694869A2 (de) * | 2003-11-10 | 2006-08-30 | Investigen, Inc. | Verfahren zur herstellung von nukleinsäure für einen nachweis |
-
2006
- 2006-06-28 JP JP2008519532A patent/JP5058160B2/ja not_active Expired - Fee Related
- 2006-06-28 AT AT06774225T patent/ATE490343T1/de not_active IP Right Cessation
- 2006-06-28 WO PCT/US2006/025233 patent/WO2007005482A1/en not_active Ceased
- 2006-06-28 DE DE602006018622T patent/DE602006018622D1/de active Active
- 2006-06-28 EP EP06774225A patent/EP1913159B1/de not_active Not-in-force
- 2006-06-29 US US11/427,395 patent/US7914983B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007005482A1 (en) | 2007-01-11 |
| JP2009501005A (ja) | 2009-01-15 |
| DE602006018622D1 (de) | 2011-01-13 |
| EP1913159B1 (de) | 2010-12-01 |
| JP5058160B2 (ja) | 2012-10-24 |
| US20070003953A1 (en) | 2007-01-04 |
| US7914983B2 (en) | 2011-03-29 |
| EP1913159A1 (de) | 2008-04-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Singer et al. | Electronic barcoding of a viral gene at the single-molecule level | |
| NZ616407A (en) | Method and product for localised or spatial detection of nucleic acid in a tissue sample | |
| DK2385141T3 (da) | Flerkomponentnukleinsyreenzymer og fremgangsmåder til anvendelse heraf | |
| Xu et al. | Chemiluminescence imaging for microRNA detection based on cascade exponential isothermal amplification machinery | |
| ATE534748T1 (de) | Direkter snp-nachweis mit nichtamplifizierter dna | |
| ATE516371T1 (de) | Oligonukleotide und deren verwendungen | |
| EP4450642A3 (de) | Einzelmolekülnukleinsäurensequenzanalyseverfahren und zusammensetzungen | |
| Li et al. | G-triplex/hemin DNAzyme: An ideal signal generator for isothermal exponential amplification reaction-based biosensing platform | |
| WO2008070144A3 (en) | Imprinted genes and disease | |
| CN103614489B (zh) | 一种登革热病毒的恒温扩增检测试剂盒及检测方法 | |
| WO2005001113A3 (en) | Methods for detecting nucleic acid variations | |
| Zhang et al. | Single-molecule fluorescence imaging for ultrasensitive DNA methyltransferase activity measurement and inhibitor screening | |
| Gao et al. | Target-promoted specific activation of m6A-DNAzyme for SPEXPAR-amplified and highly sensitive non-label electrochemical assay of FTO demethylase | |
| Zhang et al. | A label-free kissing complexes-induced fluorescence aptasensor using DNA-templated silver nanoclusters as a signal transducer | |
| CN101962685A (zh) | 一种基于液相芯片检测微小核糖核酸的方法 | |
| Xue et al. | Facile Quantification of Lesions Derived from 2 ‘-Deoxyguanosine in DNA | |
| Xie et al. | In situ amplification signaling-based autonomous aptameric machine for the sensitive fluorescence detection ofcocaine | |
| Wang et al. | Activatable self-dissociation of watson–crick structures with fluorescent nucleotides for sensing multiple human glycosylases at single-cell level | |
| Nie et al. | Entropy-driven DNA circuit with two-stage strand displacement for elegant and robust detection of miRNA let-7a | |
| Huang et al. | A DNA walker based on hairpin-shaped DNA aligner and fueled by nicking endonuclease for sensitive and rapid miRNA analysis | |
| Su et al. | Three-in-One system based on multi-path nucleic acid amplification for bioanalysis of pre-miRNA/miRNA and dicer activity | |
| DE602006012455D1 (de) | Verfahren und zusammensetzungen zum nachweis und zur analyse von nukleinsäuren mittels signalverstärkung | |
| ATE490343T1 (de) | Nachweisverfahren für die genexpression | |
| BRPI0520067A2 (pt) | desenvolvimento de um ensaio de pcr em tempo real para a detecção de dna pneumocócico e diagnóstico da doença pneumocócica | |
| WO2008112754A3 (en) | Methods, computer-accessible medium, and systems for generating a genome wide haplotype sequence |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |