ATE485037T1 - Krebsbehandlung mittels fts und 2-deoxyglucose - Google Patents

Krebsbehandlung mittels fts und 2-deoxyglucose

Info

Publication number
ATE485037T1
ATE485037T1 AT06844276T AT06844276T ATE485037T1 AT E485037 T1 ATE485037 T1 AT E485037T1 AT 06844276 T AT06844276 T AT 06844276T AT 06844276 T AT06844276 T AT 06844276T AT E485037 T1 ATE485037 T1 AT E485037T1
Authority
AT
Austria
Prior art keywords
fts
deoxyglucose
cancer treatment
analogs
disclosed
Prior art date
Application number
AT06844276T
Other languages
English (en)
Inventor
Yoel Kloog
Liat Goldberg
Michael Brownstein
Original Assignee
Univ Ramot
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ramot filed Critical Univ Ramot
Application granted granted Critical
Publication of ATE485037T1 publication Critical patent/ATE485037T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
AT06844276T 2005-11-28 2006-11-06 Krebsbehandlung mittels fts und 2-deoxyglucose ATE485037T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74009605P 2005-11-28 2005-11-28
PCT/US2006/043325 WO2007064448A2 (en) 2005-11-28 2006-11-06 Cancer treatment using fts and 2-deoxyglucose

Publications (1)

Publication Number Publication Date
ATE485037T1 true ATE485037T1 (de) 2010-11-15

Family

ID=38016969

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06844276T ATE485037T1 (de) 2005-11-28 2006-11-06 Krebsbehandlung mittels fts und 2-deoxyglucose

Country Status (5)

Country Link
US (1) US8278349B2 (de)
EP (1) EP1957060B1 (de)
AT (1) ATE485037T1 (de)
DE (1) DE602006017728D1 (de)
WO (1) WO2007064448A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2301528B1 (de) 2004-08-18 2013-04-03 Kadmon Corporation, LLC Verwendung von FTS zur Behandlung von malignen Erkrankungen
US8278349B2 (en) 2005-11-28 2012-10-02 Ramot At Tel-Aviv University Ltd. Cancer treatment using FTS and 2-deoxyglucose
WO2007101148A2 (en) * 2006-02-24 2007-09-07 Board Of Regents, The University Of Texas System Hexose compounds to treat cancer
US8232253B2 (en) 2006-12-19 2012-07-31 Ramot At Tel-Aviv University Ltd. Treatment of lung cancer
PL2282773T3 (pl) 2008-05-02 2014-08-29 Seattle Genetics Inc Sposoby i kompozycje do wytwarzania przeciwciał i pochodnych przeciwciał o obniżonej fukozylacji rdzeniowej
JP2013508458A (ja) * 2009-10-26 2013-03-07 ラモット・アット・テル−アヴィヴ・ユニヴァーシティ・リミテッド Ｆｔｓとｈｄａｃ阻害剤との組合せを用いたがん治療
EP2608796B1 (de) 2010-08-05 2018-11-21 Seattle Genetics, Inc. In-vivo-hemmung einer protein-fucosylierung mit fucose-analogen
CA2849421C (en) 2011-10-07 2020-04-28 Pisces Therapeutics Llc Malignant and non-malignant disease treatment with ras antagonists
US9738614B2 (en) 2011-10-07 2017-08-22 Pisces Therapeutics, Llc Malignant and non-malignant disease treatment with Ras antagonists
MX363385B (es) 2012-08-23 2019-03-20 Seattle Genetics Inc Métodos para el tratamiento de enfermedad de células falciformes y otras condiciones inflamatorias.
US20170326166A1 (en) * 2014-10-17 2017-11-16 University Of Virginia Patent Foundation Compositions and methods for treating pituitary tumors
CN110615891B (zh) * 2019-08-16 2020-06-23 河南大学 一类茄呢基硫代水杨酸化合物、其制备方法及应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL107587A (en) * 1993-11-12 1998-08-16 Univ Ramot Farnesyl geranyl or geranyl-geranyl derivatives pharmaceutical compositions containing them and methods for their preparation
US6462086B1 (en) * 1999-06-18 2002-10-08 Ramot University Authority For Applied Research And Industrial Development Ltd. Non-malignant disease treatment with Ras antagonists
US6670330B1 (en) * 2000-05-01 2003-12-30 Theodore J. Lampidis Cancer chemotherapy with 2-deoxy-D-glucose
US6979675B2 (en) 2003-01-10 2005-12-27 Threshold Pharmaceuticals, Inc. Treatment of cancer with 2-deoxyglucose
EP2301528B1 (de) 2004-08-18 2013-04-03 Kadmon Corporation, LLC Verwendung von FTS zur Behandlung von malignen Erkrankungen
US8278349B2 (en) 2005-11-28 2012-10-02 Ramot At Tel-Aviv University Ltd. Cancer treatment using FTS and 2-deoxyglucose
EP1986625B1 (de) 2006-02-10 2012-08-01 Ramot at Tel-Aviv University Ltd. Behandlung von ovarialkrebs
WO2007116396A1 (en) 2006-04-11 2007-10-18 Ramot At Tel Aviv University Ltd. Treatment of hematological malignancies with fts and a bcr-abl tyrosine kinase inhibitor
US8232253B2 (en) 2006-12-19 2012-07-31 Ramot At Tel-Aviv University Ltd. Treatment of lung cancer

Also Published As

Publication number Publication date
EP1957060A2 (de) 2008-08-20
WO2007064448A2 (en) 2007-06-07
WO2007064448A3 (en) 2007-08-23
DE602006017728D1 (de) 2010-12-02
EP1957060B1 (de) 2010-10-20
US8278349B2 (en) 2012-10-02
US20090286870A1 (en) 2009-11-19

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