ATE484591T1 - Minimale dna sequenz, die als chromatin-isolator wirkt, und deren verwendung für die protein- expression - Google Patents
Minimale dna sequenz, die als chromatin-isolator wirkt, und deren verwendung für die protein- expressionInfo
- Publication number
- ATE484591T1 ATE484591T1 AT04791263T AT04791263T ATE484591T1 AT E484591 T1 ATE484591 T1 AT E484591T1 AT 04791263 T AT04791263 T AT 04791263T AT 04791263 T AT04791263 T AT 04791263T AT E484591 T1 ATE484591 T1 AT E484591T1
- Authority
- AT
- Austria
- Prior art keywords
- dna sequence
- protein expression
- chromatin insulator
- minimal dna
- sequence acting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/465—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03103890 | 2003-10-21 | ||
| PCT/EP2004/052591 WO2005040384A1 (en) | 2003-10-21 | 2004-10-20 | Minimal dna sequence acting as a chromatin insulator and its use in protein expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE484591T1 true ATE484591T1 (de) | 2010-10-15 |
Family
ID=34486337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04791263T ATE484591T1 (de) | 2003-10-21 | 2004-10-20 | Minimale dna sequenz, die als chromatin-isolator wirkt, und deren verwendung für die protein- expression |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8133699B2 (de) |
| EP (1) | EP1675956B1 (de) |
| JP (1) | JP4745972B2 (de) |
| AT (1) | ATE484591T1 (de) |
| AU (1) | AU2004284243B2 (de) |
| CA (1) | CA2541523A1 (de) |
| CY (1) | CY1110868T1 (de) |
| DE (1) | DE602004029598D1 (de) |
| DK (1) | DK1675956T3 (de) |
| ES (1) | ES2354160T3 (de) |
| HR (1) | HRP20100560T1 (de) |
| IL (1) | IL175021A (de) |
| NO (1) | NO338767B1 (de) |
| PL (1) | PL1675956T3 (de) |
| PT (1) | PT1675956E (de) |
| SI (1) | SI1675956T1 (de) |
| WO (1) | WO2005040384A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1395669B1 (de) | 2001-01-26 | 2009-07-22 | Selexis S.A. | Matrix-anheftungsregionen und verfahren zu deren verwendung |
| ATE399872T1 (de) * | 2003-03-11 | 2008-07-15 | Serono Lab | Expressionvektoren, die den promotor des ie2-gens des maus cytomegalovirus enthalten |
| DK1622939T3 (da) * | 2003-05-13 | 2012-04-10 | Merck Serono Sa | Aktive varianter af det IL-18-bindende protein og medicinske anvendelser deraf |
| PL1959011T3 (pl) | 2003-10-24 | 2012-07-31 | Selexis Sa | Wysokowydajny transfer genu i ekspresja w komórkach ssaczych przez procedurę wielokrotnej transfekcji sekwencji regionu przylegania do macierzy |
| ES2285543T3 (es) * | 2003-11-05 | 2007-11-16 | Ares Trading S.A. | Procedimiento para la purificacion de la proteina de union a il-18. |
| DE602005002829T2 (de) * | 2004-03-01 | 2008-07-10 | Ares Trading S.A. | Verwendung eines serumfreien zellkulturmediums zur produktion von il-18bp in säugerzellen |
| AU2005259269B2 (en) * | 2004-06-29 | 2010-12-09 | Ares Trading S.A. | Process for the purification of IL-18 binding protein |
| ES2385639T3 (es) * | 2005-06-03 | 2012-07-27 | Ares Trading S.A. | Producción de una proteína de unión a IL-18 recombinante |
| AU2006256763B2 (en) * | 2005-06-10 | 2012-08-02 | Ares Trading S.A. | Process for the purification of IL-18 binding protein |
| EP1760092A1 (de) * | 2005-08-26 | 2007-03-07 | Applied Research Systems ARS Holding N.V. | System für Screening von Zellen mit hoher Expression von einem interessierenden Protein |
| FR2919616A1 (fr) * | 2007-08-02 | 2009-02-06 | Ecole Norm Superieure Lyon | Polynucleotides insulateurs derives de l'element d4z4 et leurs utilisations en transgenese |
| EP2697375B1 (de) | 2011-04-13 | 2017-10-18 | National Research Council of Canada | Expressionssystem mit einem kerngerüst-anheftungsregions-element aus interferon 2 |
| CA2857755A1 (en) * | 2011-12-21 | 2013-06-27 | Danisco Us Inc. | Improving fungal gene expression using insulator dna sequences |
| KR102055438B1 (ko) | 2012-07-31 | 2019-12-19 | 에이지엑스 쎄라퓨틱스, 인크. | Hla g-변형된 세포 및 방법 |
| KR101591823B1 (ko) * | 2013-12-27 | 2016-02-04 | 재단법인 목암생명공학연구소 | 증가된 유전자 발현능을 갖는 발현벡터 |
| US11246896B2 (en) | 2015-10-28 | 2022-02-15 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Tumor-specific adenovirus vectors and therapeutic uses |
| CN115141836B (zh) * | 2015-10-28 | 2024-08-27 | 桑格摩生物治疗股份有限公司 | 肝特异性构建体、因子viii表达盒及其使用方法 |
| AU2017290389B2 (en) | 2016-07-01 | 2024-09-26 | Resolve Therapeutics, Llc | Optimized binuclease fusions and methods |
| CN106754817B (zh) * | 2016-11-03 | 2021-02-05 | 山西省生物研究院有限公司 | 一种重组自分泌运动因子的表达方法 |
| US10947295B2 (en) | 2017-08-22 | 2021-03-16 | Sanabio, Llc | Heterodimers of soluble interferon receptors and uses thereof |
| CA3100946A1 (en) | 2018-05-22 | 2019-11-28 | The Brigham And Women's Hospital, Inc. | Gene therapy for alzheimer's disease |
| EP3829650A4 (de) | 2018-08-03 | 2022-05-04 | Sangamo Therapeutics, Inc. | Verbesserte klinische parameter durch expression von faktor viii |
| EP3976637A4 (de) | 2019-05-24 | 2023-07-12 | The Brigham and Women's Hospital, Inc. | Gentherapie für morbus alzheimer |
| KR20220108096A (ko) * | 2019-11-29 | 2022-08-02 | 파로스 바이오, 인코포레이티드 | 신경퇴행성 질환에 대한 유전자 요법 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| US6113898A (en) * | 1995-06-07 | 2000-09-05 | Idec Pharmaceuticals Corporation | Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies |
| US6432700B1 (en) * | 1997-03-03 | 2002-08-13 | Cell Genesys, Inc. | Adenovirus vectors containing heterologous transcription regulatory elements and methods of using same |
| US6194152B1 (en) * | 1997-08-20 | 2001-02-27 | Dendreon Corporation | Prostate tumor polynucleotide compositions and methods of detection thereof |
| AU1128400A (en) * | 1998-10-22 | 2000-05-08 | Medical College Of Georgia Institute, Inc. | Long terminal repeat, enhancer, and insulator sequences for use in recombinant vectors |
| JP2003504016A (ja) | 1999-06-30 | 2003-02-04 | アメリカ合衆国 | 遺伝子発現の制御のための特異的エンハンサー遮断活性を有する絶縁体としてのｄｎａ結合タンパク質および配列 |
| ATE399872T1 (de) | 2003-03-11 | 2008-07-15 | Serono Lab | Expressionvektoren, die den promotor des ie2-gens des maus cytomegalovirus enthalten |
| DK1622939T3 (da) | 2003-05-13 | 2012-04-10 | Merck Serono Sa | Aktive varianter af det IL-18-bindende protein og medicinske anvendelser deraf |
| ES2285543T3 (es) | 2003-11-05 | 2007-11-16 | Ares Trading S.A. | Procedimiento para la purificacion de la proteina de union a il-18. |
| DE602005002829T2 (de) | 2004-03-01 | 2008-07-10 | Ares Trading S.A. | Verwendung eines serumfreien zellkulturmediums zur produktion von il-18bp in säugerzellen |
| AU2005259269B2 (en) | 2004-06-29 | 2010-12-09 | Ares Trading S.A. | Process for the purification of IL-18 binding protein |
| ES2385639T3 (es) | 2005-06-03 | 2012-07-27 | Ares Trading S.A. | Producción de una proteína de unión a IL-18 recombinante |
| AU2006256763B2 (en) | 2005-06-10 | 2012-08-02 | Ares Trading S.A. | Process for the purification of IL-18 binding protein |
-
2004
- 2004-10-20 AT AT04791263T patent/ATE484591T1/de active
- 2004-10-20 ES ES04791263T patent/ES2354160T3/es not_active Expired - Lifetime
- 2004-10-20 SI SI200431541T patent/SI1675956T1/sl unknown
- 2004-10-20 PT PT04791263T patent/PT1675956E/pt unknown
- 2004-10-20 CA CA002541523A patent/CA2541523A1/en not_active Abandoned
- 2004-10-20 DK DK04791263.9T patent/DK1675956T3/da active
- 2004-10-20 EP EP04791263A patent/EP1675956B1/de not_active Expired - Lifetime
- 2004-10-20 AU AU2004284243A patent/AU2004284243B2/en not_active Expired
- 2004-10-20 PL PL04791263T patent/PL1675956T3/pl unknown
- 2004-10-20 JP JP2006536087A patent/JP4745972B2/ja not_active Expired - Lifetime
- 2004-10-20 WO PCT/EP2004/052591 patent/WO2005040384A1/en not_active Ceased
- 2004-10-20 US US10/576,509 patent/US8133699B2/en active Active
- 2004-10-20 HR HR20100560T patent/HRP20100560T1/hr unknown
- 2004-10-20 DE DE602004029598T patent/DE602004029598D1/de not_active Expired - Lifetime
-
2006
- 2006-04-20 IL IL175021A patent/IL175021A/en active IP Right Grant
- 2006-05-22 NO NO20062315A patent/NO338767B1/no unknown
-
2010
- 2010-10-29 CY CY20101100982T patent/CY1110868T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO338767B1 (no) | 2016-10-17 |
| US8133699B2 (en) | 2012-03-13 |
| PL1675956T3 (pl) | 2011-06-30 |
| WO2005040384A1 (en) | 2005-05-06 |
| NO20062315L (no) | 2006-07-18 |
| CY1110868T1 (el) | 2015-06-10 |
| DK1675956T3 (da) | 2010-11-22 |
| EP1675956B1 (de) | 2010-10-13 |
| JP2007508833A (ja) | 2007-04-12 |
| US20070134761A1 (en) | 2007-06-14 |
| AU2004284243A1 (en) | 2005-05-06 |
| PT1675956E (pt) | 2010-11-04 |
| EP1675956A1 (de) | 2006-07-05 |
| SI1675956T1 (sl) | 2010-12-31 |
| CA2541523A1 (en) | 2005-05-06 |
| IL175021A0 (en) | 2006-08-20 |
| DE602004029598D1 (de) | 2010-11-25 |
| AU2004284243B2 (en) | 2010-11-04 |
| JP4745972B2 (ja) | 2011-08-10 |
| IL175021A (en) | 2011-07-31 |
| HRP20100560T1 (hr) | 2010-11-30 |
| ES2354160T3 (es) | 2011-03-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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