ATE482691T1 - Amorphes aripiprazol und verfahren zu seiner herstellung - Google Patents
Amorphes aripiprazol und verfahren zu seiner herstellungInfo
- Publication number
- ATE482691T1 ATE482691T1 AT08150576T AT08150576T ATE482691T1 AT E482691 T1 ATE482691 T1 AT E482691T1 AT 08150576 T AT08150576 T AT 08150576T AT 08150576 T AT08150576 T AT 08150576T AT E482691 T1 ATE482691 T1 AT E482691T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- amorphous aripiprazole
- aripiprazole
- amorphous
- preparing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08150576A EP2082735B1 (de) | 2008-01-23 | 2008-01-23 | Amorphes Aripiprazol und Verfahren zu seiner Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE482691T1 true ATE482691T1 (de) | 2010-10-15 |
Family
ID=39529818
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08150576T ATE482691T1 (de) | 2008-01-23 | 2008-01-23 | Amorphes aripiprazol und verfahren zu seiner herstellung |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP2082735B1 (de) |
AT (1) | ATE482691T1 (de) |
DE (1) | DE602008002809D1 (de) |
ES (1) | ES2353444T3 (de) |
PL (1) | PL2082735T3 (de) |
PT (1) | PT2082735E (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TR201000948A1 (tr) * | 2010-02-09 | 2011-08-22 | Sanovel İlaç San.Ve Ti̇c.A.Ş. | Aripiprazol formülasyonları. |
DE102010019416A1 (de) * | 2010-05-04 | 2011-11-10 | Stada Arzneimittel Ag | Schmelztablette, umfassend ein Triptan oder ein atypisches Neuroleptikum |
CN108078941A (zh) * | 2018-02-07 | 2018-05-29 | 瑞阳制药有限公司 | 阿立哌唑口崩片及其制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54130587A (en) | 1978-03-30 | 1979-10-09 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
US5006528A (en) | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
JP4310605B2 (ja) | 2001-05-25 | 2009-08-12 | 大塚製薬株式会社 | 医薬用組成物 |
AR033485A1 (es) * | 2001-09-25 | 2003-12-26 | Otsuka Pharma Co Ltd | Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma |
AU2003230192A1 (en) | 2003-03-21 | 2004-10-11 | Hetero Drugs Limited | Novel crystalline forms of aripiprazole |
WO2004106322A2 (en) | 2003-04-25 | 2004-12-09 | Cadila Healthcare Limited | Polymorphs of aripiprazole |
US7456181B2 (en) | 2003-07-25 | 2008-11-25 | Hetero Drugs Limited | Aripiprazole crystalline forms |
CA2550726A1 (en) | 2003-12-16 | 2005-06-30 | Teva Pharmaceutical Industries Ltd. | Methods of preparing aripiprazole crystalline forms |
EP1880714A1 (de) * | 2006-07-20 | 2008-01-23 | Helm AG | Amorphes Aripiprazol und Verfahren zu dessen Herstellung |
-
2008
- 2008-01-23 DE DE602008002809T patent/DE602008002809D1/de active Active
- 2008-01-23 PT PT08150576T patent/PT2082735E/pt unknown
- 2008-01-23 ES ES08150576T patent/ES2353444T3/es active Active
- 2008-01-23 EP EP08150576A patent/EP2082735B1/de active Active
- 2008-01-23 PL PL08150576T patent/PL2082735T3/pl unknown
- 2008-01-23 AT AT08150576T patent/ATE482691T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE602008002809D1 (de) | 2010-11-11 |
ES2353444T3 (es) | 2011-03-02 |
EP2082735B1 (de) | 2010-09-29 |
EP2082735A1 (de) | 2009-07-29 |
PT2082735E (pt) | 2010-10-12 |
PL2082735T3 (pl) | 2011-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |