ATE476506T1 - Modulatoren des cholesterinbiosynthesewegs und verwendungen davon - Google Patents

Modulatoren des cholesterinbiosynthesewegs und verwendungen davon

Info

Publication number
ATE476506T1
ATE476506T1 AT04736173T AT04736173T ATE476506T1 AT E476506 T1 ATE476506 T1 AT E476506T1 AT 04736173 T AT04736173 T AT 04736173T AT 04736173 T AT04736173 T AT 04736173T AT E476506 T1 ATE476506 T1 AT E476506T1
Authority
AT
Austria
Prior art keywords
cholesterol
fragment
variant
derivative
seq
Prior art date
Application number
AT04736173T
Other languages
English (en)
Inventor
Kandiah Jeyaseelan
Arunmozhiarasi Armugam
Siaw Ching Chai
Prabhakaran N Ramkishen
Ponnampalam Gopalakrishnakone
Kwong Huat Tan
Original Assignee
Univ Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Singapore filed Critical Univ Singapore
Application granted granted Critical
Publication of ATE476506T1 publication Critical patent/ATE476506T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43522—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from scorpions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Insects & Arthropods (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AT04736173T 2003-06-05 2004-06-04 Modulatoren des cholesterinbiosynthesewegs und verwendungen davon ATE476506T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47620803P 2003-06-05 2003-06-05
PCT/SG2004/000168 WO2004108928A1 (en) 2003-06-05 2004-06-04 Cholesterol biosynthesis pathway modulators and uses thereof

Publications (1)

Publication Number Publication Date
ATE476506T1 true ATE476506T1 (de) 2010-08-15

Family

ID=33511764

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04736173T ATE476506T1 (de) 2003-06-05 2004-06-04 Modulatoren des cholesterinbiosynthesewegs und verwendungen davon

Country Status (5)

Country Link
US (1) US20060222638A1 (de)
EP (1) EP1636365B1 (de)
AT (1) ATE476506T1 (de)
DE (1) DE602004028469D1 (de)
WO (1) WO2004108928A1 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622985A (en) * 1990-06-11 1997-04-22 Bristol-Myers Squibb Company Method for preventing a second heart attack employing an HMG CoA reductase inhibitor
US6369103B1 (en) * 1994-01-18 2002-04-09 Bristol-Myers Squibb Company Method for preventing or reducing risk of onset of cardiovascular events employing an HMG CoA reductase inhibitor
US5902805A (en) * 1996-04-22 1999-05-11 L'oreal Method for treatment of acne and/or the effects of ageing using HMG-coenzyme A-reductase inhibitor and compositions for performing the same

Also Published As

Publication number Publication date
EP1636365B1 (de) 2010-08-04
WO2004108928A1 (en) 2004-12-16
DE602004028469D1 (de) 2010-09-16
EP1636365A1 (de) 2006-03-22
US20060222638A1 (en) 2006-10-05

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties