ATE473969T1 - Proliferationshemmende verbindungen aus einem 3- aryl-coumarin oder einem 3-aryl-chinolin-2-on und anwendungen davon - Google Patents

Proliferationshemmende verbindungen aus einem 3- aryl-coumarin oder einem 3-aryl-chinolin-2-on und anwendungen davon

Info

Publication number
ATE473969T1
ATE473969T1 AT07789580T AT07789580T ATE473969T1 AT E473969 T1 ATE473969 T1 AT E473969T1 AT 07789580 T AT07789580 T AT 07789580T AT 07789580 T AT07789580 T AT 07789580T AT E473969 T1 ATE473969 T1 AT E473969T1
Authority
AT
Austria
Prior art keywords
aryl
quinolin
antproliferation
coumarin
compounds
Prior art date
Application number
AT07789580T
Other languages
English (en)
Inventor
Matthieu Schapira
Cyrile Lamigeon
Mathieu Gutmann
Audrey Barthelaix
Nicolas Hugo
Pierre Colas
Original Assignee
Eos Ethical Oncology Science S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eos Ethical Oncology Science S filed Critical Eos Ethical Oncology Science S
Application granted granted Critical
Publication of ATE473969T1 publication Critical patent/ATE473969T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
AT07789580T 2006-05-22 2007-05-22 Proliferationshemmende verbindungen aus einem 3- aryl-coumarin oder einem 3-aryl-chinolin-2-on und anwendungen davon ATE473969T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06290821A EP1860104A1 (de) 2006-05-22 2006-05-22 Von 3-Arylcoumarin oder 3-Arylchinolin-2-on abgeleitete antiproliferative Verbindungen und ihre Verwendung
PCT/IB2007/002179 WO2007135565A2 (en) 2006-05-22 2007-05-22 Anti-proliferative compounds deriving from a 3-aryl-coumarine or 3-aryl-quinolin-2-one and uses thereof

Publications (1)

Publication Number Publication Date
ATE473969T1 true ATE473969T1 (de) 2010-07-15

Family

ID=37075181

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07789580T ATE473969T1 (de) 2006-05-22 2007-05-22 Proliferationshemmende verbindungen aus einem 3- aryl-coumarin oder einem 3-aryl-chinolin-2-on und anwendungen davon

Country Status (7)

Country Link
US (1) US20090203685A1 (de)
EP (2) EP1860104A1 (de)
JP (1) JP2009538290A (de)
CN (1) CN101448811A (de)
AT (1) ATE473969T1 (de)
DE (1) DE602007007757D1 (de)
WO (1) WO2007135565A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115403549B (zh) * 2022-08-30 2023-05-26 郑州大学 蛇床子素硫脲类衍生物、及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2781218B1 (fr) * 1998-07-15 2001-09-07 Lafon Labor Compositions pharmaceutiques comprenant des 2-quinolones
IL144003A0 (en) * 1998-12-30 2002-04-21 Signal Pharm Inc Compounds and methods for modulation of estrogen receptors
WO2003020698A2 (en) * 2001-09-06 2003-03-13 Prochon Biotech Ltd. Protein tyrosine kinase inhibitors
WO2004072043A1 (en) * 2003-02-11 2004-08-26 Warner-Lambert Company Llc Benzyl urea and thiourea derivatives useful as androgen antagonists

Also Published As

Publication number Publication date
EP2021333A2 (de) 2009-02-11
US20090203685A1 (en) 2009-08-13
EP2021333B1 (de) 2010-07-14
EP1860104A1 (de) 2007-11-28
DE602007007757D1 (de) 2010-08-26
WO2007135565A2 (en) 2007-11-29
WO2007135565A3 (en) 2008-04-03
JP2009538290A (ja) 2009-11-05
CN101448811A (zh) 2009-06-03

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Legal Events

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