ATE466104T1 - Als indikatoren zur patientenprognose geeignete haplotypen von plasminogenaktivator-inhibitor-1 (pai-1) - Google Patents
Als indikatoren zur patientenprognose geeignete haplotypen von plasminogenaktivator-inhibitor-1 (pai-1)Info
- Publication number
- ATE466104T1 ATE466104T1 AT04721788T AT04721788T ATE466104T1 AT E466104 T1 ATE466104 T1 AT E466104T1 AT 04721788 T AT04721788 T AT 04721788T AT 04721788 T AT04721788 T AT 04721788T AT E466104 T1 ATE466104 T1 AT E466104T1
- Authority
- AT
- Austria
- Prior art keywords
- patient
- pai
- inflammatory condition
- genotype
- plasminogen activator
- Prior art date
Links
- 102000012335 Plasminogen Activator Inhibitor 1 Human genes 0.000 title abstract 5
- 108010022233 Plasminogen Activator Inhibitor 1 Proteins 0.000 title abstract 5
- 238000004393 prognosis Methods 0.000 title abstract 3
- 102000054766 genetic haplotypes Human genes 0.000 title 1
- 230000004968 inflammatory condition Effects 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- 102000054765 polymorphisms of proteins Human genes 0.000 abstract 2
- 208000031729 Bacteremia Diseases 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 101000610236 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) Protein PatA Proteins 0.000 abstract 1
- 206010040047 Sepsis Diseases 0.000 abstract 1
- 206010040070 Septic Shock Diseases 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 230000004768 organ dysfunction Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 230000036303 septic shock Effects 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 230000009897 systematic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000008733 trauma Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45555003P | 2003-03-19 | 2003-03-19 | |
| PCT/CA2004/000424 WO2004083457A1 (en) | 2003-03-19 | 2004-03-19 | Plasminogen activator inhibitor-1 (pai-1) haplotypes useful as indicators of patient outcome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE466104T1 true ATE466104T1 (de) | 2010-05-15 |
Family
ID=33030019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04721788T ATE466104T1 (de) | 2003-03-19 | 2004-03-19 | Als indikatoren zur patientenprognose geeignete haplotypen von plasminogenaktivator-inhibitor-1 (pai-1) |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20060246451A1 (de) |
| EP (2) | EP1618208B1 (de) |
| JP (1) | JP2006520199A (de) |
| AT (1) | ATE466104T1 (de) |
| CA (1) | CA2519362A1 (de) |
| DE (1) | DE602004026854D1 (de) |
| ES (1) | ES2346881T3 (de) |
| WO (1) | WO2004083457A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060269946A1 (en) * | 2005-05-10 | 2006-11-30 | Young Robert P | Methods and compositions for assessment of pulmonary function and disorders |
| WO2006136033A1 (en) * | 2005-06-23 | 2006-12-28 | The University Of British Columbia | Coagulation factor iii polymorphisms associated with prediction of subject outcome and response to therapy |
| AU2007209725A1 (en) * | 2006-01-24 | 2007-08-02 | Sirius Genomics Inc. | Vasopressin pathway polymorphisms as indicators of subject outcome in critically ill subjects |
| CA2678436A1 (en) * | 2007-02-16 | 2008-08-21 | The University Of British Columbia | Serpine1 polymorphisms are predictive of response to activated protein c administration and risk of death |
| CN116574801A (zh) * | 2023-06-07 | 2023-08-11 | 北京中康博生物科技有限公司 | Pai-1基因启动子4g/5g多态性检测试剂盒、组合物及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6270961B1 (en) | 1987-04-01 | 2001-08-07 | Hyseq, Inc. | Methods and apparatus for DNA sequencing and DNA identification |
| US5866413A (en) * | 1989-03-06 | 1999-02-02 | Board Of Regents Of The University Of Texas System | Pai-1 mutants |
| US5128247A (en) | 1989-08-14 | 1992-07-07 | Board Of Regents, The University Of Texas System | Methods for isolation of nucleic acids from eukaryotic and prokaryotic sources |
| US5130423A (en) | 1990-07-13 | 1992-07-14 | Microprobe Corporation | Non-corrosive compositions and methods useful for the extraction of nucleic acids |
| EP0682671A4 (de) | 1993-02-01 | 1998-01-14 | Seq Ltd | Verfahren und geräte zur sequenzierung von dns. |
| US5922852A (en) * | 1995-06-07 | 1999-07-13 | Oklahoma Medical Research Foundation | 3' untranslated region of the human prohibitin gene |
| JPH11507544A (ja) | 1995-06-08 | 1999-07-06 | プロジェン インダストリーズ リミテッド | Ｄｎａを抽出するための方法及び装置 |
| US5945515A (en) | 1995-07-31 | 1999-08-31 | Chomczynski; Piotr | Product and process for isolating DNA, RNA and proteins |
| NL1005047C2 (nl) * | 1997-01-20 | 1998-07-22 | Tno | Werkwijze en kit voor het diagnostiseren van verhoogd risico op hart- en vaataandoeningen. |
| US6599704B2 (en) * | 1997-03-04 | 2003-07-29 | Christoph Wagener | Method for detecting mutated alleles |
| CA2290510A1 (en) * | 1997-05-21 | 1998-11-26 | Gesellschaft Fur Biotechnologische Forschung Mbh (Gbf) | Method and kit for detecting dna mutations using restriction enzymes |
| US6767540B2 (en) * | 2000-01-14 | 2004-07-27 | Tanox, Inc. | Use of antagonists of plasminogen activator inhibitor-1 (PAI-1) for the treatment of asthma and chronic obstructive pulmonary disease |
| EP1285090A1 (de) | 2000-04-25 | 2003-02-26 | DNA Sciences, Inc. | Nachweis von nukleiotidsequenzvariationen mittels der korrekturleseaktivität von polymerasen |
-
2004
- 2004-03-19 DE DE602004026854T patent/DE602004026854D1/de not_active Expired - Lifetime
- 2004-03-19 US US10/549,804 patent/US20060246451A1/en not_active Abandoned
- 2004-03-19 AT AT04721788T patent/ATE466104T1/de not_active IP Right Cessation
- 2004-03-19 EP EP04721788A patent/EP1618208B1/de not_active Expired - Lifetime
- 2004-03-19 WO PCT/CA2004/000424 patent/WO2004083457A1/en active Application Filing
- 2004-03-19 ES ES04721788T patent/ES2346881T3/es not_active Expired - Lifetime
- 2004-03-19 EP EP10154345A patent/EP2199410A1/de not_active Withdrawn
- 2004-03-19 JP JP2006504085A patent/JP2006520199A/ja active Pending
- 2004-03-19 CA CA002519362A patent/CA2519362A1/en not_active Abandoned
-
2010
- 2010-10-07 US US12/900,387 patent/US20110104683A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1618208A1 (de) | 2006-01-25 |
| WO2004083457A1 (en) | 2004-09-30 |
| CA2519362A1 (en) | 2004-09-30 |
| EP2199410A1 (de) | 2010-06-23 |
| US20110104683A1 (en) | 2011-05-05 |
| DE602004026854D1 (de) | 2010-06-10 |
| US20060246451A1 (en) | 2006-11-02 |
| JP2006520199A (ja) | 2006-09-07 |
| ES2346881T3 (es) | 2010-10-21 |
| EP1618208B1 (de) | 2010-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |