ATE461706T1 - Verwendung eines antikörpers anti-pthrp(34-53) als antagonist von pthrp zur behandlung von nierenzellkarzinoma - Google Patents
Verwendung eines antikörpers anti-pthrp(34-53) als antagonist von pthrp zur behandlung von nierenzellkarzinomaInfo
- Publication number
- ATE461706T1 ATE461706T1 AT03748201T AT03748201T ATE461706T1 AT E461706 T1 ATE461706 T1 AT E461706T1 AT 03748201 T AT03748201 T AT 03748201T AT 03748201 T AT03748201 T AT 03748201T AT E461706 T1 ATE461706 T1 AT E461706T1
- Authority
- AT
- Austria
- Prior art keywords
- pthrp
- cell carcinoma
- renal cell
- antagonist
- antibody
- Prior art date
Links
- 208000006265 Renal cell carcinoma Diseases 0.000 title abstract 3
- 239000005557 antagonist Substances 0.000 title abstract 2
- 101150071808 PTHLH gene Proteins 0.000 title 1
- 208000008839 Kidney Neoplasms Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 108700020797 Parathyroid Hormone-Related Proteins 0.000 abstract 1
- 102000043299 Parathyroid hormone-related Human genes 0.000 abstract 1
- 206010038389 Renal cancer Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000011161 development Methods 0.000 abstract 1
- 230000018109 developmental process Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 201000010982 kidney cancer Diseases 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- 230000009401 metastasis Effects 0.000 abstract 1
- 230000001394 metastastic effect Effects 0.000 abstract 1
- 206010061289 metastatic neoplasm Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000004614 tumor growth Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Marine Sciences & Fisheries (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0208501A FR2841788B1 (fr) | 2002-07-05 | 2002-07-05 | Utilisation d'antagonistes de la pthrp pour traiter le carcinome a cellules renales |
| PCT/FR2003/002084 WO2004004756A1 (fr) | 2002-07-05 | 2003-07-04 | UTILISATION D'ANTAGONISTES DE LA PTHrP POUR TRAITER LE CARCINOME A CELLULES RENALES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE461706T1 true ATE461706T1 (de) | 2010-04-15 |
Family
ID=29725229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03748201T ATE461706T1 (de) | 2002-07-05 | 2003-07-04 | Verwendung eines antikörpers anti-pthrp(34-53) als antagonist von pthrp zur behandlung von nierenzellkarzinoma |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7727526B2 (de) |
| EP (1) | EP1521591B1 (de) |
| AT (1) | ATE461706T1 (de) |
| AU (1) | AU2003267511A1 (de) |
| DE (1) | DE60331834D1 (de) |
| FR (1) | FR2841788B1 (de) |
| WO (1) | WO2004004756A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8501929B2 (en) * | 2007-08-17 | 2013-08-06 | Biochrom Pharma Inc. | PTHrP, its isoforms and antagonist thereto in the diagnosis and treatment of disease |
| US7897139B2 (en) * | 2007-08-17 | 2011-03-01 | Biochrom Pharma, Inc. | PTHrP, its isoforms and antagonist thereto in the diagnosis and treatment of disease |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4231106B2 (ja) | 1995-01-23 | 2009-02-25 | ゼノテック インコーポレイティッド | 骨溶解および転移を改善する方法 |
| JP2000513201A (ja) | 1995-07-20 | 2000-10-10 | アイ・シー・エヌ・フアーマシユーテイカルズ | 上皮小体ホルモン様たんぱく質に関連する化合物および方法 |
| RU2198220C2 (ru) | 1996-09-26 | 2003-02-10 | Чугаи Сейяку Кабусики Кайся | Антитело против белка, родственного паращитовидному гормону человека, днк, вектор, способ получения и использование антитела |
| CA2373885A1 (en) * | 1999-07-02 | 2001-01-11 | Chugai Seiyaku Kabushiki Kaisha | Therapeutic agent for diseases caused by pth or pthrp |
| AU2001252618A1 (en) * | 2000-04-28 | 2001-11-12 | Chugai Seiyaku Kabushiki Kaisha | Cell proliferation inhibitors |
| IT1318517B1 (it) | 2000-05-12 | 2003-08-27 | Ist Naz Stud Cura Dei Tumori | Polinucleotidi codificanti per forme polimorfiche della proteinapthrp, le proteine codificate, e loro applicazioni terapeutiche. |
-
2002
- 2002-07-05 FR FR0208501A patent/FR2841788B1/fr not_active Expired - Fee Related
-
2003
- 2003-07-04 WO PCT/FR2003/002084 patent/WO2004004756A1/fr not_active Application Discontinuation
- 2003-07-04 DE DE60331834T patent/DE60331834D1/de not_active Expired - Fee Related
- 2003-07-04 AT AT03748201T patent/ATE461706T1/de not_active IP Right Cessation
- 2003-07-04 EP EP03748201A patent/EP1521591B1/de not_active Expired - Lifetime
- 2003-07-04 AU AU2003267511A patent/AU2003267511A1/en not_active Abandoned
- 2003-07-04 US US10/520,085 patent/US7727526B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004004756A8 (fr) | 2004-06-10 |
| US7727526B2 (en) | 2010-06-01 |
| EP1521591B1 (de) | 2010-03-24 |
| WO2004004756A1 (fr) | 2004-01-15 |
| FR2841788B1 (fr) | 2006-01-27 |
| DE60331834D1 (de) | 2010-05-06 |
| AU2003267511A1 (en) | 2004-01-23 |
| AU2003267511A8 (en) | 2004-01-23 |
| EP1521591A1 (de) | 2005-04-13 |
| FR2841788A1 (fr) | 2004-01-09 |
| US20060003916A1 (en) | 2006-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |