ATE456958T1 - Mannose als adjuvant für intranasale vakzine - Google Patents
Mannose als adjuvant für intranasale vakzineInfo
- Publication number
- ATE456958T1 ATE456958T1 AT01937864T AT01937864T ATE456958T1 AT E456958 T1 ATE456958 T1 AT E456958T1 AT 01937864 T AT01937864 T AT 01937864T AT 01937864 T AT01937864 T AT 01937864T AT E456958 T1 ATE456958 T1 AT E456958T1
- Authority
- AT
- Austria
- Prior art keywords
- mannose
- adjuvant
- intranasal vaccines
- subject
- vaccine composition
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 239000002671 adjuvant Substances 0.000 title 1
- GZCGUPFRVQAUEE-KVTDHHQDSA-N aldehydo-D-mannose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)C=O GZCGUPFRVQAUEE-KVTDHHQDSA-N 0.000 title 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 206010022000 influenza Diseases 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0208—Specific bacteria not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/15—Reoviridae, e.g. calf diarrhea virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPQ7977A AUPQ797700A0 (en) | 2000-06-06 | 2000-06-06 | Vaccine |
| PCT/AU2001/000669 WO2001093912A1 (en) | 2000-06-06 | 2001-06-06 | Vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE456958T1 true ATE456958T1 (de) | 2010-02-15 |
Family
ID=3822049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01937864T ATE456958T1 (de) | 2000-06-06 | 2001-06-06 | Mannose als adjuvant für intranasale vakzine |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20040043032A1 (de) |
| EP (2) | EP1301208B1 (de) |
| AT (1) | ATE456958T1 (de) |
| AU (4) | AUPQ797700A0 (de) |
| DE (1) | DE60141243D1 (de) |
| HK (1) | HK1056830A1 (de) |
| WO (1) | WO2001093912A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ797700A0 (en) * | 2000-06-06 | 2000-06-29 | Austin Research Institute, The | Vaccine |
| WO2008037033A1 (en) * | 2006-09-29 | 2008-04-03 | The Macfarlane Burnet Institute For Medical Research And Public Health Limited | Flu vaccine admixture of mannan and flu antigen |
| JP2003286191A (ja) * | 2002-03-27 | 2003-10-07 | Univ Nihon | 歯周病用粘膜免疫ワクチン |
| EP1617805A4 (de) * | 2003-04-11 | 2012-07-04 | Medimmune Llc | Verfahren zur prävention oder behandlung von atemwegserkrankungen |
| EP1921919B1 (de) | 2005-07-14 | 2012-04-04 | Lithera, Inc. | Verbesserte lipolytikum-formulierung mit hinhaltender wirkstofffreigabe für die arealbehandlung von fettgewebe |
| WO2007018152A1 (ja) * | 2005-08-05 | 2007-02-15 | The University Of Tokushima | IgA抗体の選択的産生からIgA及びIgG両抗体産生への切換えを可能にする抗原薬物ビークルとこれを用いる経鼻・粘膜ワクチン |
| US20080031872A1 (en) * | 2006-08-02 | 2008-02-07 | Karp Nelson M | HIV immunogenic composition and method of administration |
| EP2077830B1 (de) * | 2006-10-17 | 2012-11-07 | Lithera, Inc. | Prozesse, zusammensetzungen u. formulierungen zur behandlung der schilddrüsen augenkrankheit |
| US9132084B2 (en) * | 2009-05-27 | 2015-09-15 | Neothetics, Inc. | Methods for administration and formulations for the treatment of regional adipose tissue |
| BR112012017556A2 (pt) * | 2010-01-15 | 2016-08-16 | Lithera Inc | formulações de torta liofilizada |
| AU2011226992B2 (en) * | 2010-05-10 | 2012-03-22 | Ascend Biopharmaceuticals Pty Ltd | Immunostimulatory and vaccine compositions |
| GB2485885B (en) | 2010-11-24 | 2015-06-17 | Neothetics Inc | Selective, lipophilic, and long-acting beta agonist monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging |
| JP2014532799A (ja) * | 2011-11-09 | 2014-12-08 | アセンド・バイオファーマシューティカルズ・リミテッド | 免疫調節結合体 |
| JP2024511959A (ja) * | 2021-03-12 | 2024-03-18 | ザ チルドレンズ メディカル センター コーポレーション | ウイルスワクチン用の多糖類アジュバント |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU620149B2 (en) | 1988-08-18 | 1992-02-13 | Vaxine Pty Ltd | Gamma inulin compositions |
| US5804200A (en) * | 1991-02-12 | 1998-09-08 | Colorado State University Research Foundation | Parasitic nematode proteins and vaccines |
| AUPM322393A0 (en) * | 1993-12-24 | 1994-01-27 | Austin Research Institute, The | Mucin carbohydrate compounds and their use in immunotherapy |
| US5597807A (en) * | 1994-08-01 | 1997-01-28 | University Of Saskatchewan | Quinoa saponin compositions and methods of use |
| US6548643B1 (en) * | 1994-11-16 | 2003-04-15 | Austin Research Institute | Antigen carbohydrate compounds and their use in immunotherapy |
| AUPN568095A0 (en) | 1995-09-27 | 1995-10-26 | Austin Research Institute, The | Anti-Galalpha(1,3)Gal antibody binding peptides |
| DE69736779T2 (de) * | 1996-12-20 | 2007-08-16 | Merck & Co., Inc. | Zusammensetzungen von rekombinanten papillomavirus vakzinen |
| ATE422893T1 (de) * | 1997-09-29 | 2009-03-15 | Macfarlane Burnet Inst For Med | Mannose-rezeptor tragende zellinie und antigen zusammensetzung |
| ATE296105T1 (de) * | 1997-10-03 | 2005-06-15 | Galenica Pharmaceuticals Inc | Iminbildende polysaccharide, deren herstellung und verwendung als zusatzmittel und immunstimulierende mittel |
| JP2002513028A (ja) * | 1998-04-28 | 2002-05-08 | ガレニカ ファーマシューティカルズ， インコーポレイテッド | ポリサッカリド抗原結合体 |
| US6555115B1 (en) * | 1998-12-08 | 2003-04-29 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| DE69942774D1 (de) | 1999-02-26 | 2010-10-28 | Novartis Vaccines & Diagnostic | Verwendung von bioadhaesiven und adjuvantien für die mukosale anwendung von antigenen |
| ATE413190T1 (de) * | 1999-12-01 | 2008-11-15 | Novartis Vaccines & Diagnostic | Hervorrufen von antikörpern spezifisch für hepatitis c virus (hcv) |
| CA2399026A1 (en) | 2000-02-01 | 2001-08-09 | The Austin Research Institute | Mucin-1 derived antigens and their use in immunotherapy |
| AU2001263653B2 (en) * | 2000-06-06 | 2006-06-29 | Igavax Pty Ltd | Vaccine |
| AUPQ797700A0 (en) * | 2000-06-06 | 2000-06-29 | Austin Research Institute, The | Vaccine |
-
2000
- 2000-06-06 AU AUPQ7977A patent/AUPQ797700A0/en not_active Abandoned
-
2001
- 2001-06-06 DE DE60141243T patent/DE60141243D1/de not_active Expired - Lifetime
- 2001-06-06 EP EP01937864A patent/EP1301208B1/de not_active Expired - Lifetime
- 2001-06-06 AT AT01937864T patent/ATE456958T1/de not_active IP Right Cessation
- 2001-06-06 WO PCT/AU2001/000669 patent/WO2001093912A1/en active Application Filing
- 2001-06-06 AU AU6365301A patent/AU6365301A/xx active Pending
- 2001-06-06 US US10/297,256 patent/US20040043032A1/en not_active Abandoned
-
2003
- 2003-10-15 HK HK03107477.4A patent/HK1056830A1/xx not_active IP Right Cessation
-
2006
- 2006-09-29 AU AU2006222717A patent/AU2006222717A1/en not_active Abandoned
-
2007
- 2007-10-02 EP EP07815271A patent/EP2066332A4/de not_active Withdrawn
- 2007-10-02 AU AU2007302633A patent/AU2007302633A1/en not_active Abandoned
- 2007-10-02 US US12/443,048 patent/US8182821B2/en not_active Expired - Fee Related
-
2010
- 2010-06-11 US US12/813,982 patent/US20110033493A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2066332A1 (de) | 2009-06-10 |
| US8182821B2 (en) | 2012-05-22 |
| AU6365301A (en) | 2001-12-17 |
| EP1301208A1 (de) | 2003-04-16 |
| US20100008951A1 (en) | 2010-01-14 |
| EP1301208A4 (de) | 2004-11-17 |
| DE60141243D1 (de) | 2010-03-25 |
| AU2007302633A1 (en) | 2008-04-03 |
| US20110033493A1 (en) | 2011-02-10 |
| EP2066332A4 (de) | 2012-01-18 |
| HK1056830A1 (en) | 2004-03-05 |
| EP1301208B1 (de) | 2010-02-03 |
| AU2006222717A1 (en) | 2006-10-19 |
| WO2001093912A1 (en) | 2001-12-13 |
| US20040043032A1 (en) | 2004-03-04 |
| AUPQ797700A0 (en) | 2000-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |