ATE45162T1 - Ester von boranaloga von aminosaeuren. - Google Patents
Ester von boranaloga von aminosaeuren.Info
- Publication number
- ATE45162T1 ATE45162T1 AT85307732T AT85307732T ATE45162T1 AT E45162 T1 ATE45162 T1 AT E45162T1 AT 85307732 T AT85307732 T AT 85307732T AT 85307732 T AT85307732 T AT 85307732T AT E45162 T1 ATE45162 T1 AT E45162T1
- Authority
- AT
- Austria
- Prior art keywords
- esters
- boranalogues
- amino acids
- haloalkyl
- proviso
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol group Chemical group [C@@H]1(CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)[C@H](C)CCCC(C)C HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 1
- KKAXNAVSOBXHTE-UHFFFAOYSA-N boranamine Chemical class NB KKAXNAVSOBXHTE-UHFFFAOYSA-N 0.000 abstract 1
- KOXIGEBRUGYXFD-UHFFFAOYSA-N boranylformic acid Chemical compound BC(O)=O KOXIGEBRUGYXFD-UHFFFAOYSA-N 0.000 abstract 1
- FZFAMSAMCHXGEF-UHFFFAOYSA-N chloro formate Chemical compound ClOC=O FZFAMSAMCHXGEF-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000005270 trialkylamine group Chemical group 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1896—Compounds having one or more Si-O-acyl linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/664,647 US4647555A (en) | 1984-10-25 | 1984-10-25 | Esters of boron analogues of amino acids |
| EP85307732A EP0181721B1 (de) | 1984-10-25 | 1985-10-25 | Ester von Boranaloga von Aminosäuren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE45162T1 true ATE45162T1 (de) | 1989-08-15 |
Family
ID=24666855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85307732T ATE45162T1 (de) | 1984-10-25 | 1985-10-25 | Ester von boranaloga von aminosaeuren. |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4647555A (de) |
| EP (1) | EP0181721B1 (de) |
| AT (1) | ATE45162T1 (de) |
| DE (1) | DE3571988D1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2610522B1 (fr) * | 1987-02-06 | 1989-08-18 | Gueyne Jean | Produit therapeutique a base de derives organiques du silicium |
| US5023513A (en) * | 1989-06-09 | 1991-06-11 | Boron Biologicals, Inc. | Amine-alkylborane derivatives and methods |
| US5260427A (en) * | 1991-05-10 | 1993-11-09 | Boron Biolgicals, Inc. | Nucleosidylphosphite-borane compounds and method of making the same |
| US5143907A (en) * | 1991-05-10 | 1992-09-01 | Boron Biologicals, Inc. | Phosphite-borane compounds, and method of making and using the same |
| GB0111872D0 (en) | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
| US7968605B2 (en) | 2002-02-04 | 2011-06-28 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
| AU2003208525B9 (en) | 2002-02-04 | 2009-08-27 | Alfama-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda | Amend the invention title to read Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof |
| GB0601394D0 (en) | 2006-01-24 | 2006-03-01 | Hemocorm Ltd | Therapeutic delivery of carbon monoxide |
| EP2699242B1 (de) | 2011-04-19 | 2017-11-01 | Alfama, Inc. | Kohlenmonoxidfreisetzende moleküle und ihre verwendungen |
| EP2734235B1 (de) | 2011-07-21 | 2017-03-22 | Alfama, Inc. | Kohlenmonoxidfreisetzende rutheniummoleküle und ihre verwendungen |
| EP2881398A1 (de) | 2013-12-04 | 2015-06-10 | Université de Bordeaux I | Verfahren zur Herstellung von Aminoarylboranverbindungen oder Derivaten davon |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US312989A (en) * | 1885-02-24 | John t | ||
| US3018299A (en) * | 1960-07-01 | 1962-01-23 | Union Carbide Corp | Aryl borate addition compounds of amino hydrocarbon silicon compounds |
| US3265737A (en) * | 1964-11-03 | 1966-08-09 | Du Pont | Boron amines and process for formation thereof |
| US4035409A (en) * | 1974-12-18 | 1977-07-12 | Texaco Inc. | Hydrocarbyl amine substituted propionic ester |
| DE3070534D1 (en) * | 1979-12-21 | 1985-05-23 | Univ Duke | Pharmacologically active amine-carboxyboranes |
| US4440941A (en) * | 1980-12-22 | 1984-04-03 | Usv Pharmaceutical Corporation | Aroyl-aminoacids, amides and esters thereof |
-
1984
- 1984-10-25 US US06/664,647 patent/US4647555A/en not_active Expired - Fee Related
-
1985
- 1985-10-25 DE DE8585307732T patent/DE3571988D1/de not_active Expired
- 1985-10-25 EP EP85307732A patent/EP0181721B1/de not_active Expired
- 1985-10-25 AT AT85307732T patent/ATE45162T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0181721B1 (de) | 1989-08-02 |
| US4647555A (en) | 1987-03-03 |
| DE3571988D1 (en) | 1989-09-07 |
| EP0181721A1 (de) | 1986-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |