ATE44740T1 - Heterocyclische, dissymmetrische 1,4dihydropyridin-3,5-dicarboxylsaeureester, verfahren zu ihrer herstellung und ihre verwendung in heilmitteln. - Google Patents

Heterocyclische, dissymmetrische 1,4dihydropyridin-3,5-dicarboxylsaeureester, verfahren zu ihrer herstellung und ihre verwendung in heilmitteln.

Info

Publication number
ATE44740T1
ATE44740T1 AT86400273T AT86400273T ATE44740T1 AT E44740 T1 ATE44740 T1 AT E44740T1 AT 86400273 T AT86400273 T AT 86400273T AT 86400273 T AT86400273 T AT 86400273T AT E44740 T1 ATE44740 T1 AT E44740T1
Authority
AT
Austria
Prior art keywords
heterocyclic
dissymmetric
medicines
preparation
different
Prior art date
Application number
AT86400273T
Other languages
English (en)
Inventor
Jacques Robin
Didier Pruneau
Alain Bonenfant
Original Assignee
Fournier Innovation Synergie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Innovation Synergie filed Critical Fournier Innovation Synergie
Application granted granted Critical
Publication of ATE44740T1 publication Critical patent/ATE44740T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
AT86400273T 1985-02-20 1986-02-10 Heterocyclische, dissymmetrische 1,4dihydropyridin-3,5-dicarboxylsaeureester, verfahren zu ihrer herstellung und ihre verwendung in heilmitteln. ATE44740T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8502412A FR2577552B1 (fr) 1985-02-20 1985-02-20 Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique
EP86400273A EP0194906B1 (de) 1985-02-20 1986-02-10 Heterocyclische, dissymmetrische 1,4-Dihydropyridin-3,5-dicarboxylsäureester, Verfahren zu ihrer Herstellung und ihre Verwendung in Heilmitteln

Publications (1)

Publication Number Publication Date
ATE44740T1 true ATE44740T1 (de) 1989-08-15

Family

ID=9316449

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86400273T ATE44740T1 (de) 1985-02-20 1986-02-10 Heterocyclische, dissymmetrische 1,4dihydropyridin-3,5-dicarboxylsaeureester, verfahren zu ihrer herstellung und ihre verwendung in heilmitteln.

Country Status (8)

Country Link
US (1) US4710505A (de)
EP (1) EP0194906B1 (de)
JP (1) JPS61194084A (de)
AT (1) ATE44740T1 (de)
DE (1) DE3664470D1 (de)
ES (1) ES8802043A1 (de)
FR (1) FR2577552B1 (de)
PT (1) PT82042B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2596760B1 (fr) * 1986-04-02 1988-12-09 Sori Soc Rech Ind Derives dissymetriques de l'acide 1,4-dihydropyridine-3,5-dicarboxylique, procedes de preparation et utilisation en therapeutique
IT1205834B (it) * 1987-04-22 1989-03-31 Elbart Derivati tiodiossolanici ad attivita' mucolitica a procedimento per la loro preparazione
US4808729A (en) * 1987-09-24 1989-02-28 G. D. Searle & Co. Leukotriene LTD4 and LTB4 antagonists
US4923891A (en) * 1987-09-24 1990-05-08 G. D. Searle & Co. Leukotriene LTD4 and LTB4 antagonists
US4912223A (en) * 1988-01-28 1990-03-27 Nelson Research & Development Co. 1,4-Dihydropyridines
AT391471B (de) * 1988-05-13 1990-10-10 Gerot Pharmazeutika Neue derivate von 5-aminomethyl-2-furanmethanol, ihre herstellung und verwendung
NZ227921A (en) * 1988-05-30 1991-06-25 Embalaje Iberoamericana Stackable container: reinforcing corner flaps
US4870098A (en) * 1989-01-17 1989-09-26 G. D. Searle & Co. Antagonists of leukotriene D4
WO2011032095A1 (en) * 2009-09-11 2011-03-17 Segetis, Inc. Ketal esters of oxocarboxylic acids and process of making
US20170107325A1 (en) * 2014-03-31 2017-04-20 Nof Corporation Hydrophilic polymer derivative having cyclic benzylidene acetal linker

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2641746C2 (de) * 1976-09-16 1986-11-06 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-Zuckerderivate, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
GB2111978B (en) * 1981-10-19 1985-05-01 Maruko Pharmaceutical Co 1 4-dihydropyridine compounds
FR2553407B1 (fr) * 1983-10-14 1986-01-03 Lafon Labor Derives de n-(4-acetylaminophenacyl)-amine, leur utilisation en therapeutique et leur procede de preparation

Also Published As

Publication number Publication date
EP0194906A3 (en) 1987-08-19
US4710505A (en) 1987-12-01
ES8802043A1 (es) 1988-04-01
EP0194906B1 (de) 1989-07-19
PT82042A (fr) 1986-03-01
PT82042B (pt) 1988-01-22
FR2577552A1 (fr) 1986-08-22
DE3664470D1 (en) 1989-08-24
EP0194906A2 (de) 1986-09-17
FR2577552B1 (fr) 1987-09-04
JPS61194084A (ja) 1986-08-28
ES552509A0 (es) 1988-04-01

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