ATE44465T1 - Verfahren zur waermebehandlung einer den menschlichen blutgerinnungsfaktor viii enthaltenden waessrigen loesung. - Google Patents
Verfahren zur waermebehandlung einer den menschlichen blutgerinnungsfaktor viii enthaltenden waessrigen loesung.Info
- Publication number
- ATE44465T1 ATE44465T1 AT82101408T AT82101408T ATE44465T1 AT E44465 T1 ATE44465 T1 AT E44465T1 AT 82101408 T AT82101408 T AT 82101408T AT 82101408 T AT82101408 T AT 82101408T AT E44465 T1 ATE44465 T1 AT E44465T1
- Authority
- AT
- Austria
- Prior art keywords
- factor viii
- aqueous solution
- coagaging
- heat treatment
- solution containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0023—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/04—Heat
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56173585A JPS5874617A (ja) | 1981-10-28 | 1981-10-28 | 人由来血液凝固第7因子含有水溶液の加熱処理方法 |
EP82101408A EP0077870B1 (de) | 1981-10-28 | 1982-02-24 | Verfahren zur Wärmebehandlung einer den menschlichen Blutgerinnungsfaktor VIII enthaltenden wässrigen Lösung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE44465T1 true ATE44465T1 (de) | 1989-07-15 |
Family
ID=15963301
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT82101408T ATE44465T1 (de) | 1981-10-28 | 1982-02-24 | Verfahren zur waermebehandlung einer den menschlichen blutgerinnungsfaktor viii enthaltenden waessrigen loesung. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4446134A (de) |
EP (1) | EP0077870B1 (de) |
JP (1) | JPS5874617A (de) |
AT (1) | ATE44465T1 (de) |
DE (1) | DE3279807D1 (de) |
ES (1) | ES8302772A1 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4581231A (en) * | 1982-06-10 | 1986-04-08 | The United States Of America As Represented By The Secretary Of Health And Human Services | Inactivation of viruses containing essential lipids |
DE3481109D1 (de) * | 1983-05-09 | 1990-03-01 | Novo Nordisk As | Antihaemophilie-faktor-viii-konzentrat und dessen herstellungsverfahren. |
DE3330770A1 (de) * | 1983-08-26 | 1985-03-14 | Behringwerke Ag, 3550 Marburg | Verfahren zur pasteurisierung von humanplasma |
US4615886A (en) * | 1983-08-31 | 1986-10-07 | The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Utilizing a halohydrocarbon containing dissolved water to inactivate a lipid virus |
AT389815B (de) * | 1984-03-09 | 1990-02-12 | Immuno Ag | Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten |
US4797388A (en) * | 1984-05-21 | 1989-01-10 | Cetus Corporation | Pharmaceutical compositions with galactitol as carrier |
JPH0669961B2 (ja) * | 1984-09-25 | 1994-09-07 | 株式会社ミドリ十字 | 免疫グロブリンの加熱処理方法 |
US4670394A (en) * | 1984-11-16 | 1987-06-02 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Isolation and culture of adrenal medullary endothelial cells producing blood clotting factor VIII:C |
JPH0825902B2 (ja) * | 1985-02-21 | 1996-03-13 | 株式会社ミドリ十字 | γ−グロブリンの加熱処理方法 |
AT390560B (de) * | 1986-05-30 | 1990-05-25 | Immuno Ag | Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern |
US4749783A (en) * | 1986-07-11 | 1988-06-07 | Miles Laboratories, Inc. | Viral inactivation and purification of active proteins |
DE3625090A1 (de) * | 1986-07-24 | 1988-01-28 | Behringwerke Ag | Mittel zur therapie faktor viii-resistenter haemophilie a und verfahren zu seiner herstellung |
GB8628104D0 (en) * | 1986-11-25 | 1986-12-31 | Connaught Lab | Pasteurization of immunoglobin solutions |
AU2251288A (en) * | 1987-05-15 | 1988-12-06 | Alan I. Rubinstein | Sequential improved method for treatment of human blood- clotting factor products |
IL86417A (en) * | 1987-05-22 | 1992-09-06 | Armour Pharma | Process for the inactivation of pathogens in biological or pharmaceutical material by mixing with aqueous solution containing a sugar(alcohol)and neutral salts as stabilizers |
US4876241A (en) * | 1987-05-22 | 1989-10-24 | Armour Pharmaceutical Company | Stabilization of biological and pharmaceutical products during thermal inactivation of viral and bacterial contaminants |
DE3805459A1 (de) * | 1988-02-22 | 1989-08-31 | Biotest Pharma Gmbh | Verfahren zur sterilisation von blut, plasma, blut- und plasmaderivaten, zellsuspensionen oder dgl. |
US4939176A (en) * | 1988-12-20 | 1990-07-03 | Miles Inc. | Viral inactivation process |
ES2042138T3 (es) * | 1989-05-24 | 1993-12-01 | Miles Inc. | Filtracion en gel del factor viii tratado termicamente. |
DE4001451A1 (de) * | 1990-01-19 | 1991-08-01 | Octapharma Ag | Stabile injizierbare loesungen von faktor viii und faktor ix |
AT402891B (de) * | 1991-06-20 | 1997-09-25 | Immuno Ag | Verfahren zur herstellung eines inaktivierten blutproduktes |
JP3133338B2 (ja) * | 1992-12-16 | 2001-02-05 | イムノ・アクチエンゲゼルシャフト | ウイルス的に安全な生物学的組成物の調製方法 |
JP3220539B2 (ja) * | 1992-12-25 | 2001-10-22 | 日本ケミカルリサーチ株式会社 | 活性乳蛋白成分含有製品およびその製造法 |
DE4320294A1 (de) * | 1993-06-18 | 1994-12-22 | Immuno Ag | Verwendung von humanem Protein C zur Verhinderung und Behandlung von Thrombozytenablagerungen |
US6288030B1 (en) | 1993-12-22 | 2001-09-11 | Amgen Inc. | Stem cell factor formulations and methods |
EP0888779B1 (de) * | 1996-02-05 | 2003-07-02 | Asahi Medical Co., Ltd. | Sterilisationsschutzmittel und verfahren zur sterilisation |
AUPO871997A0 (en) * | 1997-08-25 | 1997-09-18 | Csl Limited | Dried biologically or therapeutically active preparations |
CN1075736C (zh) * | 1997-12-30 | 2001-12-05 | 长春市中心血站 | 高密度脂蛋白制剂的病毒灭活方法 |
RU2244556C2 (ru) | 1999-02-22 | 2005-01-20 | Юниверсити Оф Коннектикут | Новые не содержащие альбумин составы фактора viii |
AUPR638801A0 (en) * | 2001-07-13 | 2001-08-09 | Life Therapeutics Limited | Factor viii separation |
KR100624013B1 (ko) * | 2004-06-25 | 2006-09-19 | 주식회사 녹십자홀딩스 | 동결건조된 알부민 비함유 재조합 사람 혈액응고 제 8인자 제제 |
JP5779780B2 (ja) | 2008-11-07 | 2015-09-16 | バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated | 第viii因子製剤 |
PT3135687T (pt) | 2015-08-31 | 2019-05-21 | Inst Grifols S A | Método para preparação de imunoglobulinas |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2705230A (en) * | 1949-09-23 | 1955-03-29 | Allen F Reid | Method of purifying albumin |
JPS51118820A (en) * | 1975-04-08 | 1976-10-19 | Green Cross Corp:The | A process for preparing heat stable macroglobulin |
JPS51118819A (en) * | 1975-04-08 | 1976-10-19 | Green Cross Corp:The | A process for preparing heat stable antitrypsin |
US4089944A (en) * | 1975-12-22 | 1978-05-16 | Baxter Travenol Laboratories, Inc. | Rapidly solubilized AHF composition and process for preparing same |
US4027013A (en) * | 1976-01-22 | 1977-05-31 | William L. Wilson | Clottable fibrinogen free factor VIII and albumin product and process |
DE2916711A1 (de) * | 1979-04-25 | 1980-11-06 | Behringwerke Ag | Blutgerinnungsfaktoren und verfahren zu ihrer herstellung |
JPS56135418A (en) * | 1980-03-27 | 1981-10-22 | Green Cross Corp:The | Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human |
-
1981
- 1981-10-28 JP JP56173585A patent/JPS5874617A/ja active Granted
-
1982
- 1982-02-19 US US06/350,150 patent/US4446134A/en not_active Expired - Fee Related
- 1982-02-24 DE DE8282101408T patent/DE3279807D1/de not_active Expired
- 1982-02-24 EP EP82101408A patent/EP0077870B1/de not_active Expired
- 1982-02-24 AT AT82101408T patent/ATE44465T1/de not_active IP Right Cessation
- 1982-02-26 ES ES509941A patent/ES8302772A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0077870A2 (de) | 1983-05-04 |
EP0077870B1 (de) | 1989-07-12 |
US4446134A (en) | 1984-05-01 |
EP0077870A3 (en) | 1983-11-09 |
DE3279807D1 (en) | 1989-08-17 |
ES509941A0 (es) | 1983-01-16 |
JPH0348170B2 (de) | 1991-07-23 |
JPS5874617A (ja) | 1983-05-06 |
ES8302772A1 (es) | 1983-01-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |