ATE443138T1 - Hemmung der expression von spag9 mit sirnas - Google Patents
Hemmung der expression von spag9 mit sirnasInfo
- Publication number
- ATE443138T1 ATE443138T1 AT06710485T AT06710485T ATE443138T1 AT E443138 T1 ATE443138 T1 AT E443138T1 AT 06710485 T AT06710485 T AT 06710485T AT 06710485 T AT06710485 T AT 06710485T AT E443138 T1 ATE443138 T1 AT E443138T1
- Authority
- AT
- Austria
- Prior art keywords
- spag9
- sirnas
- inhibition
- expression
- relates
- Prior art date
Links
- 102100025905 C-Jun-amino-terminal kinase-interacting protein 4 Human genes 0.000 title 1
- 101001076862 Homo sapiens C-Jun-amino-terminal kinase-interacting protein 4 Proteins 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000011275 oncology therapy Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN466DE2005 | 2005-03-02 | ||
| PCT/IB2006/000445 WO2006092714A2 (en) | 2005-03-02 | 2006-03-02 | Inhibition of spag9 expression with sirnas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE443138T1 true ATE443138T1 (de) | 2009-10-15 |
Family
ID=36763952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06710485T ATE443138T1 (de) | 2005-03-02 | 2006-03-02 | Hemmung der expression von spag9 mit sirnas |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8227591B2 (de) |
| EP (1) | EP1861496B1 (de) |
| JP (1) | JP2008531037A (de) |
| AT (1) | ATE443138T1 (de) |
| AU (1) | AU2006219666B2 (de) |
| DE (1) | DE602006009234D1 (de) |
| WO (1) | WO2006092714A2 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102590510A (zh) * | 2012-02-02 | 2012-07-18 | 任碧琼 | 抗spag9抗体在肿瘤的早期辅助诊断中的用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1390387A4 (de) * | 2001-04-20 | 2004-12-08 | Ludwig Inst Cancer Res | Hodenkrebsantigene |
| EP1432724A4 (de) * | 2002-02-20 | 2006-02-01 | Sirna Therapeutics Inc | Durch rna-interferenz vermittelte inhibierung von map-kinase-genen |
| CA2500687A1 (en) * | 2002-10-02 | 2004-04-15 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| EP2305813A3 (de) * | 2002-11-14 | 2012-03-28 | Dharmacon, Inc. | Funktionale und hyperfunktionale siRNA |
| JP2008512984A (ja) * | 2004-05-28 | 2008-05-01 | ダナ−ファーバー キャンサー インスティチュート，インコーポレイテッド | 癌の同定、評価、予防および治療のための組成物、キットおよび方法 |
-
2006
- 2006-03-02 AT AT06710485T patent/ATE443138T1/de not_active IP Right Cessation
- 2006-03-02 JP JP2007557617A patent/JP2008531037A/ja active Pending
- 2006-03-02 US US11/817,252 patent/US8227591B2/en not_active Expired - Fee Related
- 2006-03-02 EP EP06710485A patent/EP1861496B1/de not_active Expired - Lifetime
- 2006-03-02 AU AU2006219666A patent/AU2006219666B2/en not_active Ceased
- 2006-03-02 WO PCT/IB2006/000445 patent/WO2006092714A2/en not_active Ceased
- 2006-03-02 DE DE602006009234T patent/DE602006009234D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20090298740A1 (en) | 2009-12-03 |
| DE602006009234D1 (de) | 2009-10-29 |
| EP1861496A2 (de) | 2007-12-05 |
| EP1861496B1 (de) | 2009-09-16 |
| AU2006219666A1 (en) | 2006-09-08 |
| JP2008531037A (ja) | 2008-08-14 |
| AU2006219666B2 (en) | 2011-01-27 |
| US8227591B2 (en) | 2012-07-24 |
| WO2006092714A2 (en) | 2006-09-08 |
| WO2006092714A3 (en) | 2007-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |