ATE43967T1 - Antitumorale arzneimittel und verbindungen fuer behandlung von tumoren unter anwendung von (alpha, omega-bis(disubstituierte phosphino) kohlenwasserstoff> digold (i), digold (iii), disilber (i) und dikupfer (i)-derivaten. - Google Patents
Antitumorale arzneimittel und verbindungen fuer behandlung von tumoren unter anwendung von (alpha, omega-bis(disubstituierte phosphino) kohlenwasserstoff> digold (i), digold (iii), disilber (i) und dikupfer (i)-derivaten.Info
- Publication number
- ATE43967T1 ATE43967T1 AT85300681T AT85300681T ATE43967T1 AT E43967 T1 ATE43967 T1 AT E43967T1 AT 85300681 T AT85300681 T AT 85300681T AT 85300681 T AT85300681 T AT 85300681T AT E43967 T1 ATE43967 T1 AT E43967T1
- Authority
- AT
- Austria
- Prior art keywords
- digold
- dicopper
- disilver
- omega
- alpha
- Prior art date
Links
- 239000004215 Carbon black (E152) Substances 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 229930195733 hydrocarbon Natural products 0.000 title abstract 2
- 150000002430 hydrocarbons Chemical class 0.000 title abstract 2
- FVZVCSNXTFCBQU-UHFFFAOYSA-N phosphanyl Chemical class [PH2] FVZVCSNXTFCBQU-UHFFFAOYSA-N 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 238000011282 treatment Methods 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
- 230000004565 tumor cell growth Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5027—Polyphosphines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5045—Complexes or chelates of phosphines with metallic compounds or metals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57565084A | 1984-02-01 | 1984-02-01 | |
| EP85300681A EP0151046B1 (de) | 1984-02-01 | 1985-01-31 | Antitumorale Arzneimittel und Verbindungen für Behandlung von Tumoren unter Anwendung von [alpha, omega-bis(disubstituierte phosphino) Kohlenwasserstoff] digold (I), digold (III), disilber (I) und dikupfer (I)-Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE43967T1 true ATE43967T1 (de) | 1989-06-15 |
Family
ID=24301170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85300681T ATE43967T1 (de) | 1984-02-01 | 1985-01-31 | Antitumorale arzneimittel und verbindungen fuer behandlung von tumoren unter anwendung von (alpha, omega-bis(disubstituierte phosphino) kohlenwasserstoff> digold (i), digold (iii), disilber (i) und dikupfer (i)-derivaten. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0151046B1 (de) |
| JP (1) | JPS60188322A (de) |
| AT (1) | ATE43967T1 (de) |
| AU (1) | AU572949B2 (de) |
| CA (1) | CA1238854A (de) |
| DE (1) | DE3570981D1 (de) |
| DK (1) | DK40385A (de) |
| IE (1) | IE850226L (de) |
| ZA (1) | ZA85755B (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH21350A (en) * | 1984-06-04 | 1987-10-13 | Smithkline Beckman Corp | Tumor cell growth imhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes |
| US5037812A (en) * | 1985-04-02 | 1991-08-06 | Smithkline Beckman Corporation | Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes |
| US4716230A (en) * | 1985-04-16 | 1987-12-29 | Smithkline Beckman Corporation | Certain bis(di-2 or 4-pyridyl-phosphino) alkanes #10 having anti-tumor properties |
| DK166686A (da) * | 1985-04-16 | 1986-10-17 | Smithkline Beckman Corp | Phosphinforbindelser, fremgangsmaade til fremstilling heraf samt farmaceutiske midler indeholdende disse forbindelser |
| US4902675A (en) * | 1985-05-16 | 1990-02-20 | Smithkline Beckman Corporation | "2-pyridyl and 4-pyridyl phosphine gold (I) anti tumor complexes" |
| EP0202854A3 (de) * | 1985-05-20 | 1988-01-13 | Smithkline Beecham Corporation | Phosphin-Gold-Verbindungen |
| US4698422A (en) * | 1985-05-20 | 1987-10-06 | Smithkline Beckman Corporation | Triphos and tetraphos gold compounds and ligands |
| NL8502929A (nl) * | 1985-10-25 | 1987-05-18 | Tno | Groep viii-overgangsmetaal-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijke groep viii-overgangsmetaal-complex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel. |
| US4758589A (en) * | 1985-12-23 | 1988-07-19 | Smithkline Beckman Corporation | Tetraphosphine-coordinated gold(I) complexes |
| US4764509A (en) * | 1986-02-21 | 1988-08-16 | Smithkline Beckman Corporation | Pharmaceutical compositions containing di-gold phosphine |
| WO1995014703A1 (en) * | 1993-11-24 | 1995-06-01 | Luminis Pty. Ltd. | Triorganophosphinegold (i) thionucleobases with anti-tumor activity |
| WO2001077121A1 (en) * | 2000-04-10 | 2001-10-18 | National University Of Singapore | Gold complexes |
| US6774254B2 (en) | 2000-04-10 | 2004-08-10 | National University Of Singapore | Gold complexes |
| DE10300097A1 (de) * | 2003-01-07 | 2004-07-22 | Bayer Ag | Kupfer-Komplexe und ihre Verwendung |
| WO2009074305A1 (de) * | 2007-12-13 | 2009-06-18 | Biosphings Ag | Gold-xanthogenate und diese enthaltende arzneimittel |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3661959A (en) * | 1970-07-30 | 1972-05-09 | Du Pont | Method of making organogold chloride complexes |
| US3676554A (en) * | 1970-10-30 | 1972-07-11 | Smith Kline French Lab | Anti-arthritic compositions comprising phosphine or phosphite gold halide complexes and methods of producing anti-arthritic activity |
| PH21350A (en) * | 1984-06-04 | 1987-10-13 | Smithkline Beckman Corp | Tumor cell growth imhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes |
-
1985
- 1985-01-07 CA CA000471598A patent/CA1238854A/en not_active Expired
- 1985-01-29 AU AU38126/85A patent/AU572949B2/en not_active Ceased
- 1985-01-29 DK DK40385A patent/DK40385A/da not_active Application Discontinuation
- 1985-01-31 DE DE8585300681T patent/DE3570981D1/de not_active Expired
- 1985-01-31 ZA ZA85755A patent/ZA85755B/xx unknown
- 1985-01-31 IE IE850226A patent/IE850226L/xx unknown
- 1985-01-31 EP EP85300681A patent/EP0151046B1/de not_active Expired
- 1985-01-31 AT AT85300681T patent/ATE43967T1/de not_active IP Right Cessation
- 1985-02-01 JP JP60019181A patent/JPS60188322A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS60188322A (ja) | 1985-09-25 |
| EP0151046A3 (en) | 1985-08-21 |
| IE850226L (en) | 1985-08-01 |
| EP0151046A2 (de) | 1985-08-07 |
| EP0151046B1 (de) | 1989-06-14 |
| DE3570981D1 (en) | 1989-07-20 |
| AU572949B2 (en) | 1988-05-19 |
| AU3812685A (en) | 1985-08-29 |
| CA1238854A (en) | 1988-07-05 |
| DK40385D0 (da) | 1985-01-29 |
| ZA85755B (en) | 1986-05-28 |
| DK40385A (da) | 1985-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |