ATE434765T1 - Verwendung von polarisiertem 129xe zur herstellung eines medikaments zur verwendung in einem in-vivo-nmr-verfahren - Google Patents

Verwendung von polarisiertem 129xe zur herstellung eines medikaments zur verwendung in einem in-vivo-nmr-verfahren

Info

Publication number
ATE434765T1
ATE434765T1 AT02766248T AT02766248T ATE434765T1 AT E434765 T1 ATE434765 T1 AT E434765T1 AT 02766248 T AT02766248 T AT 02766248T AT 02766248 T AT02766248 T AT 02766248T AT E434765 T1 ATE434765 T1 AT E434765T1
Authority
AT
Austria
Prior art keywords
disease
polarized
disorder
methods
medicine
Prior art date
Application number
AT02766248T
Other languages
English (en)
Inventor
Bastiaan Driehuys
Margaret Hall
Claudio Marelli
Original Assignee
Medi Physics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medi Physics Inc filed Critical Medi Physics Inc
Application granted granted Critical
Publication of ATE434765T1 publication Critical patent/ATE434765T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Measuring devices for evaluating the respiratory organs
    • A61B5/0813Measurement of pulmonary parameters by tracers, e.g. radioactive tracers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026Measuring blood flow
    • A61B5/0275Measuring blood flow using tracers, e.g. dye dilution
    • A61B5/02755Radioactive tracers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Signal Processing (AREA)
  • Physiology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT02766248T 2001-09-20 2002-09-06 Verwendung von polarisiertem 129xe zur herstellung eines medikaments zur verwendung in einem in-vivo-nmr-verfahren ATE434765T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32366701P 2001-09-20 2001-09-20
PCT/US2002/028431 WO2003024324A2 (en) 2001-09-20 2002-09-06 METHODS FOR IN VIVO EVALUATION OF A PHYSIOLOGICAL STRUCTURE OR FUNCTION USING POLARIZED129Xe

Publications (1)

Publication Number Publication Date
ATE434765T1 true ATE434765T1 (de) 2009-07-15

Family

ID=23260201

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02766248T ATE434765T1 (de) 2001-09-20 2002-09-06 Verwendung von polarisiertem 129xe zur herstellung eines medikaments zur verwendung in einem in-vivo-nmr-verfahren

Country Status (10)

Country Link
US (1) US20030064024A1 (de)
EP (1) EP1430322B1 (de)
JP (2) JP4283673B2 (de)
AT (1) ATE434765T1 (de)
AU (1) AU2002329991B2 (de)
CA (1) CA2457543A1 (de)
DE (1) DE60232734D1 (de)
DK (1) DK1430322T3 (de)
ES (1) ES2327218T3 (de)
WO (1) WO2003024324A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040142496A1 (en) * 2001-04-23 2004-07-22 Nicholson Jeremy Kirk Methods for analysis of spectral data and their applications: atherosclerosis/coronary heart disease
US7179450B2 (en) * 2001-09-20 2007-02-20 Medi-Physics, Inc. Methods for in vivo evaluation of pulmonary physiology and/or function using NMR signals of polarized Xe
FR2848750B1 (fr) * 2002-12-13 2007-02-09 Centre Nat Rech Scient Procede d'acquisition de signaux electromagnetiques et produit de contraste pour une telle acquisition
DE102005048443A1 (de) 2005-10-07 2007-04-12 Linotec Development Gmbh Spinnvlies-Filmlaminat
BRPI0718198A2 (pt) 2006-10-03 2013-11-12 Univ Duke Método para fornecer dados de mri de estado de troca gasosa pulmonar e/ou de barreira capilar-alveolar, sistema e dispositivo de varredura de mri, e, produto de programa de computador
AU2008240243A1 (en) 2007-04-11 2008-10-23 Oregon Health & Science University Method and apparatus for noninvasive quantitative detection of fibrosis in the heart
RU2556590C2 (ru) * 2009-03-19 2015-07-10 Конинклейке Филипс Электроникс Н.В. Функциональная визуализация
US20110009731A1 (en) 2009-07-08 2011-01-13 Fonar Corporation Method and system for performing upright magnetic resonance imaging of various anatomical and physiological conditions
JP5595497B2 (ja) * 2009-07-20 2014-09-24 コーニンクレッカ フィリップス エヌ ヴェ 磁性粒子に影響を及ぼし、かつ前記磁性粒子を検出する装置並びに方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002507438A (ja) * 1998-03-18 2002-03-12 メディ−フィジックス・インコーポレイテッド 溶解化した極性化129Xeを用いる肺および心臓脈管構造の映像化および血流を上昇するMR方法
EP1265527A2 (de) * 2000-03-13 2002-12-18 Medi-Physics, Inc. Diagnostische verfahren unter verwendung direkter injizierung von gasförmigem hyperpolarisiertem 129 xenon

Also Published As

Publication number Publication date
DE60232734D1 (de) 2009-08-06
JP2005502418A (ja) 2005-01-27
US20030064024A1 (en) 2003-04-03
EP1430322B1 (de) 2009-06-24
ES2327218T3 (es) 2009-10-27
DK1430322T3 (da) 2009-10-19
WO2003024324A3 (en) 2003-11-20
JP4283673B2 (ja) 2009-06-24
CA2457543A1 (en) 2003-03-27
JP2009106788A (ja) 2009-05-21
WO2003024324A2 (en) 2003-03-27
AU2002329991B2 (en) 2008-09-25
EP1430322A2 (de) 2004-06-23

Similar Documents

Publication Publication Date Title
Song et al. The effects of specific respiratory rates on heart rate and heart rate variability
Reimann et al. The (un) conscious mouse as a model for human brain functions: key principles of anesthesia and their impact on translational neuroimaging
Caparros-Gonzalez et al. Listening to relaxing music improves physiological responses in premature infants: a randomized controlled trial
Bonfiglio et al. Cortical source of blink‐related delta oscillations and their correlation with levels of consciousness
Yu et al. Quantitative assessment of brain microvascular and tissue oxygenation during cardiac arrest and resuscitation in pigs
Han et al. Phase synchronization analysis of prefrontal tissue oxyhemoglobin oscillations in elderly subjects with cerebral infarction
Ross et al. Speech‐in‐noise understanding in older age: The role of inhibitory cortical responses
West et al. A porcine model for studying the cardiovascular consequences of high‐thoracic spinal cord injury
ATE434765T1 (de) Verwendung von polarisiertem 129xe zur herstellung eines medikaments zur verwendung in einem in-vivo-nmr-verfahren
Murase et al. Interstitial-fluid shear stresses induced by vertically oscillating head motion lower blood pressure in hypertensive rats and humans
Kasai et al. Early sinusoidal heart rate patterns and heart rate variability to assess hypoxia–ischaemia in near‐term fetal sheep
Weintraub et al. Auditory stream segregation impairments in schizophrenia
Ando et al. Acute hypoxia impairs posterior cerebral bioenergetics and memory in man
Takei et al. Preattentive dysfunction in bipolar disorder: a MEG study using auditory mismatch negativity
Shoemaker et al. Altered cortical activation patterns associated with baroreflex unloading following 24 h of physical deconditioning
Aizawa et al. Effects of procaterol, a beta-2-adrenoceptor stimulant, on neuroeffector transmission in human bronchial tissue
Cho et al. Refining the sensory and motor ratunculus of the rat upper extremity using fMRI and direct nerve stimulation
Koszycki et al. Influence of personality on behavioral response to cholecystokinin-tetrapeptide in patients with panic disorder
Kuipers et al. Aging attenuates the vestibulorespiratory reflex in humans
Muñoz et al. Head hemodynamics and systemic responses during auditory stimulation
Hayati et al. DIFFERENCES IN THE EFFECTS OF PSYCHORELIGENT THERAPY AND CLASSICAL MUSIC THERAPY ON REDUCING ANXIETY LEVELS IN ORTHOPEDIC PRE-OPERATION PATIENTS
Eisen et al. The effects of breathing rate and pCO2 levels on relaxation and anxiety in a non-clinical population
Orlikoff Heartbeat-related fundamental frequency and amplitude variation in healthy young and elderly male voices
KR20120000370A (ko) 마취심도 모니터링 장치 및 그를 이용한 방법
Prasetyawati et al. The Effect of Therapy Music of Natural Sound to Anxiety in the Last Batch Students

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties