ATE429415T1 - Verfahren zur kristallisierung von benzphetamin - Google Patents

Verfahren zur kristallisierung von benzphetamin

Info

Publication number
ATE429415T1
ATE429415T1 AT05816270T AT05816270T ATE429415T1 AT E429415 T1 ATE429415 T1 AT E429415T1 AT 05816270 T AT05816270 T AT 05816270T AT 05816270 T AT05816270 T AT 05816270T AT E429415 T1 ATE429415 T1 AT E429415T1
Authority
AT
Austria
Prior art keywords
crystallization
organic medium
temperature
benzphetamine
discovered
Prior art date
Application number
AT05816270T
Other languages
English (en)
Inventor
Dennis Kalota
Keith Tomazi
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Application granted granted Critical
Publication of ATE429415T1 publication Critical patent/ATE429415T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/82—Purification; Separation; Stabilisation; Use of additives
    • C07C209/84—Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT05816270T 2004-11-30 2005-11-02 Verfahren zur kristallisierung von benzphetamin ATE429415T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63163504P 2004-11-30 2004-11-30
US65658105P 2005-02-25 2005-02-25
PCT/US2005/039448 WO2006060099A1 (en) 2004-11-30 2005-11-02 Crystallization method for benzphetamine

Publications (1)

Publication Number Publication Date
ATE429415T1 true ATE429415T1 (de) 2009-05-15

Family

ID=35929609

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05816270T ATE429415T1 (de) 2004-11-30 2005-11-02 Verfahren zur kristallisierung von benzphetamin

Country Status (9)

Country Link
US (1) US7750187B2 (de)
EP (1) EP1819661B1 (de)
JP (1) JP2008521804A (de)
AT (1) ATE429415T1 (de)
AU (1) AU2005310229A1 (de)
CA (1) CA2588724A1 (de)
DE (1) DE602005014138D1 (de)
MX (1) MX2007006281A (de)
WO (1) WO2006060099A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008048254A1 (en) * 2006-10-17 2008-04-24 Mallinckrodt Inc. Highly pure crystalline benzphetamine hydrochloride and processes for preparing
JP4914759B2 (ja) 2007-05-09 2012-04-11 住友化学株式会社 晶析方法
US8569544B2 (en) * 2009-08-19 2013-10-29 Emcure Pharmaceuticals Limited Process for preparation of benzphetamine and its pharmaceutically acceptable salts
GB201212081D0 (en) * 2012-07-06 2012-08-22 Kalvista Pharmaceuticals Ltd New polymorph
CN110655466B (zh) * 2019-01-16 2023-02-24 安徽贝克制药股份有限公司 盐酸苄非他明的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1854553A (en) * 1926-05-10 1932-04-19 Nat Aniline & Chem Co Inc Production of n-substituted amines
US2789138A (en) * 1952-06-02 1957-04-16 Upjohn Co d-nu-methyl-nu-benzyl-beta-phenyliso-propylamine
US3182060A (en) * 1961-08-21 1965-05-04 Du Pont N, n'-disubstituted dicarboxamides and dithiocarboxamides prepared from monoenamines
FR2782M (fr) * 1963-08-01 1964-09-07 Amido Lab Nouveaux médicaments actifs sur le systeme nerveux autonome et possédant des propriétés anorexigenes et stimulantes sur le systeme nerveux central.
US3676558A (en) * 1970-08-28 1972-07-11 Upjohn Co Anorexigenic compositions comprising 6-alkyl-1,2,3,4,5,6-hexahydroazepino 4,5-indoles as active ingredient and process of treatment
US4277420A (en) * 1979-09-24 1981-07-07 Monsanto Company Ephedrine and pseudoephedrine precursors
US4747920A (en) * 1984-06-20 1988-05-31 Battelle Memorial Institute Solid-liquid separation process for fine particle suspensions by an electric and ultrasonic field
US5236922A (en) * 1984-08-20 1993-08-17 Laboratoire L. Lafon Method for treating depression using 1-(aminophenyl)-2-aminopropanone derivatives
CO5150225A1 (es) * 1999-03-19 2002-04-29 Merck Sharp & Dohme Derivados del tetrahidropirano y su uso como agentes terapeuticos
GB0020721D0 (en) * 2000-08-22 2000-10-11 Merck Sharp & Dohme Therapeutic agents
AU2005309960A1 (en) * 2004-11-22 2006-06-01 Mallinckrodt Inc. Process for the purification of benzphetamine hydrochloride

Also Published As

Publication number Publication date
DE602005014138D1 (de) 2009-06-04
CA2588724A1 (en) 2006-06-08
EP1819661A1 (de) 2007-08-22
US20080262268A1 (en) 2008-10-23
EP1819661B1 (de) 2009-04-22
AU2005310229A1 (en) 2006-06-08
US7750187B2 (en) 2010-07-06
WO2006060099A1 (en) 2006-06-08
JP2008521804A (ja) 2008-06-26
MX2007006281A (es) 2007-07-09

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Legal Events

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