ATE423205T1 - Verfahren zur biologischen herstellung von l- pipekolinsäure - Google Patents
Verfahren zur biologischen herstellung von l- pipekolinsäureInfo
- Publication number
- ATE423205T1 ATE423205T1 AT00985831T AT00985831T ATE423205T1 AT E423205 T1 ATE423205 T1 AT E423205T1 AT 00985831 T AT00985831 T AT 00985831T AT 00985831 T AT00985831 T AT 00985831T AT E423205 T1 ATE423205 T1 AT E423205T1
- Authority
- AT
- Austria
- Prior art keywords
- pipecolic acid
- producing
- escherichia coli
- biologically producing
- recombinant escherichia
- Prior art date
Links
- HXEACLLIILLPRG-RXMQYKEDSA-N l-pipecolic acid Natural products OC(=O)[C@H]1CCCCN1 HXEACLLIILLPRG-RXMQYKEDSA-N 0.000 title abstract 3
- HXEACLLIILLPRG-UHFFFAOYSA-N pipecolic acid Chemical compound OC(=O)C1CCCCN1 HXEACLLIILLPRG-UHFFFAOYSA-N 0.000 title abstract 3
- 241000588724 Escherichia coli Species 0.000 abstract 2
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 2
- CSDPVAKVEWETFG-UHFFFAOYSA-N 1-piperideine-6-carboxylic acid Chemical compound OC(=O)C1CCCC=N1 CSDPVAKVEWETFG-UHFFFAOYSA-N 0.000 abstract 1
- 241000186031 Corynebacteriaceae Species 0.000 abstract 1
- 235000019766 L-Lysine Nutrition 0.000 abstract 1
- 108091000123 L-Lysine 6-Transaminase Proteins 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Chemical compound OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 1
- 241000186254 coryneform bacterium Species 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0026—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y105/00—Oxidoreductases acting on the CH-NH group of donors (1.5)
- C12Y105/01—Oxidoreductases acting on the CH-NH group of donors (1.5) with NAD+ or NADP+ as acceptor (1.5.1)
- C12Y105/01002—Pyrroline-5-carboxylate reductase (1.5.1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0026—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
- C12N9/0028—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP37338999 | 1999-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE423205T1 true ATE423205T1 (de) | 2009-03-15 |
Family
ID=18502080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00985831T ATE423205T1 (de) | 1999-12-28 | 2000-12-22 | Verfahren zur biologischen herstellung von l- pipekolinsäure |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7022502B2 (de) |
| EP (1) | EP1249494B1 (de) |
| JP (1) | JP4516712B2 (de) |
| KR (1) | KR100819380B1 (de) |
| CN (1) | CN1415015B (de) |
| AT (1) | ATE423205T1 (de) |
| AU (1) | AU783140B2 (de) |
| CA (1) | CA2396439C (de) |
| DE (1) | DE60041595D1 (de) |
| ES (1) | ES2317857T3 (de) |
| WO (1) | WO2001048216A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4590981B2 (ja) * | 2003-08-26 | 2010-12-01 | 三菱化学株式会社 | 光学活性環状アミノ酸の製造方法 |
| EP2873730A4 (de) * | 2012-06-13 | 2016-05-11 | Microbiopharm Japan Co Ltd | Biologisches verfahren zur herstellung von cis-5-hydroxy-l-pipecolinsäure |
| IN2015DN02381A (de) | 2013-02-19 | 2015-09-04 | Api Corp | |
| CN104803909B (zh) * | 2015-05-25 | 2017-08-29 | 南京工业大学 | L‑哌啶甲酸的分离方法 |
| CN104974076A (zh) * | 2015-08-06 | 2015-10-14 | 南京工业大学 | 改进的l-哌啶甲酸的分离方法 |
| CN117866868B (zh) * | 2024-03-12 | 2024-05-28 | 天津科技大学 | 一种l-高脯氨酸生产菌株及其构建方法与应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3266635B2 (ja) | 1991-12-11 | 2002-03-18 | 協和醗酵工業株式会社 | １−ピペコリン酸の製造法 |
| WO2000008170A1 (en) * | 1998-08-05 | 2000-02-17 | Mercian Corporation | Gene participating in the production of homo-glutamic acid and utilization thereof |
-
2000
- 2000-12-22 ES ES00985831T patent/ES2317857T3/es not_active Expired - Lifetime
- 2000-12-22 AT AT00985831T patent/ATE423205T1/de not_active IP Right Cessation
- 2000-12-22 CN CN008179824A patent/CN1415015B/zh not_active Expired - Fee Related
- 2000-12-22 WO PCT/JP2000/009137 patent/WO2001048216A1/ja not_active Ceased
- 2000-12-22 DE DE60041595T patent/DE60041595D1/de not_active Expired - Lifetime
- 2000-12-22 KR KR1020027005415A patent/KR100819380B1/ko not_active Expired - Fee Related
- 2000-12-22 AU AU22225/01A patent/AU783140B2/en not_active Ceased
- 2000-12-22 US US10/169,257 patent/US7022502B2/en not_active Expired - Lifetime
- 2000-12-22 CA CA2396439A patent/CA2396439C/en not_active Expired - Lifetime
- 2000-12-22 JP JP2001548728A patent/JP4516712B2/ja not_active Expired - Fee Related
- 2000-12-22 EP EP00985831A patent/EP1249494B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1249494B1 (de) | 2009-02-18 |
| JPWO2001048216A1 (ja) | 2004-01-08 |
| AU2222501A (en) | 2001-07-09 |
| CN1415015B (zh) | 2011-12-14 |
| JP4516712B2 (ja) | 2010-08-04 |
| US20030207410A1 (en) | 2003-11-06 |
| CA2396439A1 (en) | 2001-07-05 |
| KR20020065494A (ko) | 2002-08-13 |
| EP1249494A1 (de) | 2002-10-16 |
| AU783140B2 (en) | 2005-09-29 |
| ES2317857T3 (es) | 2009-05-01 |
| WO2001048216A1 (en) | 2001-07-05 |
| KR100819380B1 (ko) | 2008-04-04 |
| DE60041595D1 (de) | 2009-04-02 |
| CN1415015A (zh) | 2003-04-30 |
| CA2396439C (en) | 2012-05-22 |
| EP1249494A4 (de) | 2004-06-16 |
| US7022502B2 (en) | 2006-04-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |