ATE423205T1 - Verfahren zur biologischen herstellung von l- pipekolinsäure - Google Patents

Verfahren zur biologischen herstellung von l- pipekolinsäure

Info

Publication number
ATE423205T1
ATE423205T1 AT00985831T AT00985831T ATE423205T1 AT E423205 T1 ATE423205 T1 AT E423205T1 AT 00985831 T AT00985831 T AT 00985831T AT 00985831 T AT00985831 T AT 00985831T AT E423205 T1 ATE423205 T1 AT E423205T1
Authority
AT
Austria
Prior art keywords
pipecolic acid
producing
escherichia coli
biologically producing
recombinant escherichia
Prior art date
Application number
AT00985831T
Other languages
English (en)
Inventor
Tadashi Fujii
Yasuhide Aritoku
Manabu Mukaihara
Takao Narita
Hitosi Agematu
Kunio Isshiki
Original Assignee
Mercian Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mercian Corp filed Critical Mercian Corp
Application granted granted Critical
Publication of ATE423205T1 publication Critical patent/ATE423205T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0026—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y105/00—Oxidoreductases acting on the CH-NH group of donors (1.5)
    • C12Y105/01—Oxidoreductases acting on the CH-NH group of donors (1.5) with NAD+ or NADP+ as acceptor (1.5.1)
    • C12Y105/01002—Pyrroline-5-carboxylate reductase (1.5.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0026—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
    • C12N9/0028—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
  • Steroid Compounds (AREA)
AT00985831T 1999-12-28 2000-12-22 Verfahren zur biologischen herstellung von l- pipekolinsäure ATE423205T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP37338999 1999-12-28

Publications (1)

Publication Number Publication Date
ATE423205T1 true ATE423205T1 (de) 2009-03-15

Family

ID=18502080

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00985831T ATE423205T1 (de) 1999-12-28 2000-12-22 Verfahren zur biologischen herstellung von l- pipekolinsäure

Country Status (11)

Country Link
US (1) US7022502B2 (de)
EP (1) EP1249494B1 (de)
JP (1) JP4516712B2 (de)
KR (1) KR100819380B1 (de)
CN (1) CN1415015B (de)
AT (1) ATE423205T1 (de)
AU (1) AU783140B2 (de)
CA (1) CA2396439C (de)
DE (1) DE60041595D1 (de)
ES (1) ES2317857T3 (de)
WO (1) WO2001048216A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4590981B2 (ja) * 2003-08-26 2010-12-01 三菱化学株式会社 光学活性環状アミノ酸の製造方法
CN104395466A (zh) * 2012-06-13 2015-03-04 日本迈科洛生物制药有限公司 顺式-5-羟基-l-六氢吡啶甲酸的生物学制备方法
CN104685061B (zh) 2013-02-19 2018-05-01 株式会社Api L-赖氨酸羟化酶和利用了该l-赖氨酸羟化酶的羟基-l-赖氨酸的制造法及羟基-l-2-哌啶酸的制造法
CN104803909B (zh) * 2015-05-25 2017-08-29 南京工业大学 L‑哌啶甲酸的分离方法
CN104974076A (zh) * 2015-08-06 2015-10-14 南京工业大学 改进的l-哌啶甲酸的分离方法
CN117866868B (zh) * 2024-03-12 2024-05-28 天津科技大学 一种l-高脯氨酸生产菌株及其构建方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3266635B2 (ja) 1991-12-11 2002-03-18 協和醗酵工業株式会社 １−ピペコリン酸の製造法
CN1229497C (zh) * 1998-08-05 2005-11-30 美露香株式会社 与高谷氨酸生产相关的基因及其应用

Also Published As

Publication number Publication date
JPWO2001048216A1 (ja) 2004-01-08
CN1415015B (zh) 2011-12-14
EP1249494A1 (de) 2002-10-16
AU783140B2 (en) 2005-09-29
EP1249494A4 (de) 2004-06-16
KR20020065494A (ko) 2002-08-13
DE60041595D1 (de) 2009-04-02
JP4516712B2 (ja) 2010-08-04
CA2396439C (en) 2012-05-22
ES2317857T3 (es) 2009-05-01
US20030207410A1 (en) 2003-11-06
AU2222501A (en) 2001-07-09
CN1415015A (zh) 2003-04-30
EP1249494B1 (de) 2009-02-18
WO2001048216A1 (fr) 2001-07-05
CA2396439A1 (en) 2001-07-05
KR100819380B1 (ko) 2008-04-04
US7022502B2 (en) 2006-04-04

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