ATE416765T1 - Methode zur extraktion antineoplastischer substanzen aus bupleurum scorzonerifolium und lactone enthaltende zusammensetzung - Google Patents
Methode zur extraktion antineoplastischer substanzen aus bupleurum scorzonerifolium und lactone enthaltende zusammensetzungInfo
- Publication number
- ATE416765T1 ATE416765T1 AT03450241T AT03450241T ATE416765T1 AT E416765 T1 ATE416765 T1 AT E416765T1 AT 03450241 T AT03450241 T AT 03450241T AT 03450241 T AT03450241 T AT 03450241T AT E416765 T1 ATE416765 T1 AT E416765T1
- Authority
- AT
- Austria
- Prior art keywords
- antineoplastic
- bupleurum scorzonerifolium
- components
- chaihulactone
- agent
- Prior art date
Links
- 241000213015 Bupleurum scorzonerifolium Species 0.000 title abstract 4
- 230000000118 anti-neoplastic effect Effects 0.000 title abstract 4
- 239000000126 substance Substances 0.000 title abstract 2
- 238000000605 extraction Methods 0.000 title 1
- 150000002596 lactones Chemical class 0.000 title 1
- CJLVKDPRUXBTJQ-UHFFFAOYSA-N chaihulactone Natural products COC1=C(OC)C(OC)=CC(C=C2C(OCC2CC=2C=C3OCOC3=CC=2)=O)=C1 CJLVKDPRUXBTJQ-UHFFFAOYSA-N 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 2
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract 2
- CJLVKDPRUXBTJQ-BESIOYJRSA-N (3z,4r)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methylidene]oxolan-2-one Chemical compound COC1=C(OC)C(OC)=CC(\C=C\2C(OC[C@@H]/2CC=2C=C3OCOC3=CC=2)=O)=C1 CJLVKDPRUXBTJQ-BESIOYJRSA-N 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 229930012538 Paclitaxel Natural products 0.000 abstract 1
- 108010017842 Telomerase Proteins 0.000 abstract 1
- 239000002259 anti human immunodeficiency virus agent Substances 0.000 abstract 1
- 229940124411 anti-hiv antiviral agent Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229960001592 paclitaxel Drugs 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 239000012747 synergistic agent Substances 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03450241A EP1527784B1 (de) | 2003-10-28 | 2003-10-28 | Methode zur Extraktion antineoplastischer Substanzen aus Bupleurum scorzonerifolium und Lactone enthaltende Zusammensetzung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE416765T1 true ATE416765T1 (de) | 2008-12-15 |
Family
ID=34400649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03450241T ATE416765T1 (de) | 2003-10-28 | 2003-10-28 | Methode zur extraktion antineoplastischer substanzen aus bupleurum scorzonerifolium und lactone enthaltende zusammensetzung |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1527784B1 (de) |
| AT (1) | ATE416765T1 (de) |
| DE (1) | DE60325220D1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP2667A (en) * | 2006-05-25 | 2013-05-17 | Csir | Treatment of erectile dysfunction and libido enhancement |
| CN102940720A (zh) * | 2012-11-22 | 2013-02-27 | 山东省立医院 | 一种用于抗肝癌的中药复方制剂 |
| JP6763604B2 (ja) * | 2016-10-04 | 2020-09-30 | 日本メナード化粧品株式会社 | 幹細胞の未分化状態維持剤及び増殖促進剤 |
-
2003
- 2003-10-28 AT AT03450241T patent/ATE416765T1/de not_active IP Right Cessation
- 2003-10-28 DE DE60325220T patent/DE60325220D1/de not_active Expired - Lifetime
- 2003-10-28 EP EP03450241A patent/EP1527784B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1527784A1 (de) | 2005-05-04 |
| DE60325220D1 (de) | 2009-01-22 |
| EP1527784B1 (de) | 2008-12-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |