ATE413414T1 - Kaliumabhängiger natrium-calcium-austauscher - Google Patents
Kaliumabhängiger natrium-calcium-austauscherInfo
- Publication number
- ATE413414T1 ATE413414T1 AT03766674T AT03766674T ATE413414T1 AT E413414 T1 ATE413414 T1 AT E413414T1 AT 03766674 T AT03766674 T AT 03766674T AT 03766674 T AT03766674 T AT 03766674T AT E413414 T1 ATE413414 T1 AT E413414T1
- Authority
- AT
- Austria
- Prior art keywords
- polypeptide
- potassium
- dependent sodium
- calcium exchanger
- expression vector
- Prior art date
Links
- 108010010579 potassium-dependent sodium-calcium exchanger Proteins 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 239000013604 expression vector Substances 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000005779 cell damage Effects 0.000 abstract 1
- 208000037887 cell injury Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 230000010410 reperfusion Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biotechnology (AREA)
- Cardiology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Zoology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002225114 | 2002-08-01 | ||
| JP2003182989 | 2003-06-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE413414T1 true ATE413414T1 (de) | 2008-11-15 |
Family
ID=31497615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03766674T ATE413414T1 (de) | 2002-08-01 | 2003-07-31 | Kaliumabhängiger natrium-calcium-austauscher |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7264935B2 (de) |
| EP (1) | EP1526140B1 (de) |
| JP (1) | JP4380536B2 (de) |
| AT (1) | ATE413414T1 (de) |
| AU (1) | AU2003252754A1 (de) |
| CA (1) | CA2480427C (de) |
| DE (1) | DE60324562D1 (de) |
| ES (1) | ES2314252T3 (de) |
| WO (1) | WO2004013173A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101657720A (zh) * | 2006-05-31 | 2010-02-24 | 荷兰联合利华有限公司 | 筛选改变皮肤和/或头发色素沉着的化合物的方法 |
| EP2215473A1 (de) * | 2007-11-27 | 2010-08-11 | Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House | Screening-verfahren |
| EP2103939A1 (de) * | 2008-03-20 | 2009-09-23 | sanofi-aventis | Fluoreszenzbasiertes Assay zur Detektion von Modulationskomponenten des Natrium-/Kalziumaustauschers (NCX) im Umkehrmodus |
| EP2103944A1 (de) * | 2008-03-20 | 2009-09-23 | sanofi-aventis | Fluoreszenz-basiertes Assay zum Erkennen von Substanzen, die den "forward mode" des Natrium/Calcium Austauschers modulieren |
| CN106620645A (zh) * | 2010-07-09 | 2017-05-10 | 康德生物医疗技术公司 | 预防或治疗缺血/再灌注损伤之后无复流的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0967336A (ja) * | 1995-09-04 | 1997-03-11 | Kanebo Ltd | 新規なイソチオウレア誘導体 |
| AU2001252084B2 (en) * | 2000-04-28 | 2006-07-06 | Inflazyme Pharmaceuticals Limited | 3-nitrogen-6,7-dioxygen steroids and uses related thereto |
| CA2423942A1 (en) * | 2000-09-27 | 2002-04-04 | Lexicon Genetics Incorporated | Human ion-exchanger proteins and polynucleotides encoding the same |
-
2003
- 2003-07-31 CA CA2480427A patent/CA2480427C/en not_active Expired - Fee Related
- 2003-07-31 DE DE60324562T patent/DE60324562D1/de not_active Expired - Lifetime
- 2003-07-31 JP JP2004525805A patent/JP4380536B2/ja not_active Expired - Fee Related
- 2003-07-31 AU AU2003252754A patent/AU2003252754A1/en not_active Abandoned
- 2003-07-31 WO PCT/JP2003/009732 patent/WO2004013173A1/ja active Application Filing
- 2003-07-31 ES ES03766674T patent/ES2314252T3/es not_active Expired - Lifetime
- 2003-07-31 EP EP03766674A patent/EP1526140B1/de not_active Expired - Lifetime
- 2003-07-31 US US10/506,624 patent/US7264935B2/en not_active Expired - Fee Related
- 2003-07-31 AT AT03766674T patent/ATE413414T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1526140A4 (de) | 2006-03-08 |
| CA2480427C (en) | 2010-08-31 |
| DE60324562D1 (de) | 2008-12-18 |
| CA2480427A1 (en) | 2004-02-12 |
| US7264935B2 (en) | 2007-09-04 |
| EP1526140B1 (de) | 2008-11-05 |
| ES2314252T3 (es) | 2009-03-16 |
| US20050119173A1 (en) | 2005-06-02 |
| AU2003252754A1 (en) | 2004-02-23 |
| WO2004013173A1 (ja) | 2004-02-12 |
| JP4380536B2 (ja) | 2009-12-09 |
| JPWO2004013173A1 (ja) | 2006-09-21 |
| EP1526140A1 (de) | 2005-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |