ATE413378T1 - Verfahren zur herstellung von phenylethylaminen, insbesondere venlafaxin - Google Patents

Verfahren zur herstellung von phenylethylaminen, insbesondere venlafaxin

Info

Publication number
ATE413378T1
ATE413378T1 AT02743616T AT02743616T ATE413378T1 AT E413378 T1 ATE413378 T1 AT E413378T1 AT 02743616 T AT02743616 T AT 02743616T AT 02743616 T AT02743616 T AT 02743616T AT E413378 T1 ATE413378 T1 AT E413378T1
Authority
AT
Austria
Prior art keywords
alkyl
general formula
carbon atom
compounds
precursor
Prior art date
Application number
AT02743616T
Other languages
English (en)
Inventor
Jagdish Chand Saigal
Rajender Pershad Gupta
Vilas Vasant Pandit
Anand Jagannath Desai
Navneet Vinodrai Mehta
Shrikant Hambirrao Rane
Original Assignee
Nicholas Piramal India Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicholas Piramal India Ltd filed Critical Nicholas Piramal India Ltd
Application granted granted Critical
Publication of ATE413378T1 publication Critical patent/ATE413378T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/48Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT02743616T 2002-03-26 2002-06-13 Verfahren zur herstellung von phenylethylaminen, insbesondere venlafaxin ATE413378T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN208CH2002 2002-03-26

Publications (1)

Publication Number Publication Date
ATE413378T1 true ATE413378T1 (de) 2008-11-15

Family

ID=28053434

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02743616T ATE413378T1 (de) 2002-03-26 2002-06-13 Verfahren zur herstellung von phenylethylaminen, insbesondere venlafaxin

Country Status (8)

Country Link
US (1) US7026513B2 (de)
EP (1) EP1490325B1 (de)
AT (1) ATE413378T1 (de)
AU (1) AU2002345346B2 (de)
CA (1) CA2482569C (de)
DE (1) DE60229789D1 (de)
NZ (1) NZ535548A (de)
WO (1) WO2003080560A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10359154A1 (de) * 2003-12-16 2005-07-28 Krka Tovarna Zdravil, D.D. Verfahren zur Herstellung von Venlafaxin und Venlafaxinhydrochlorid der Form I
EP1721889A1 (de) * 2005-05-12 2006-11-15 Dishman Pharmaceuticals & Chemicals Ltd. Verfahren zur Herstellung von Phenethylaminderivaten
KR20080056311A (ko) * 2005-10-19 2008-06-20 테바 파마슈티컬 인더스트리즈 리미티드 고순도1-[2-디메틸아미노-(4-메톡시페닐)에틸)시클로헥산올염산염의 제조 방법
MX2007016179A (es) * 2006-04-17 2008-03-11 Teva Pharma Formas cristalinas de o-desmetilvenlafaxina.
US20090069601A1 (en) * 2006-07-26 2009-03-12 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
US20090062572A1 (en) * 2006-07-26 2009-03-05 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
US20090137846A1 (en) * 2006-07-26 2009-05-28 Valerie Niddam-Hildesheim Processes for the synthesis of O-Desmethylvenlafaxine
US20080221356A1 (en) * 2006-07-26 2008-09-11 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
TR200909798T1 (tr) * 2007-07-12 2010-05-21 Dr. Reddy's Laboratories Ltd. O-desmetilvenlafaksin.
WO2009151494A1 (en) * 2008-03-06 2009-12-17 Teva Pharmaceutical Industries Ltd. Processes for the preparation of o-desmethylvenlafaxine, free from its dimer impurities
WO2009144517A1 (en) * 2008-04-14 2009-12-03 Egis Gyógyszergyár Nyilvánosan Müködö Process for the preparation of cyclohexanol derivatives
EP2297087A2 (de) * 2008-06-16 2011-03-23 Teva Pharmaceutical Industries Ltd. Feste formen von o-desmethylvenlafaxinsalzen
EP2539313A2 (de) * 2010-03-29 2013-01-02 Pliva Hrvatska D.O.O. Kristalline formen von o-desmethylvenlafaxinfumarat
CN106866434B (zh) * 2017-02-14 2018-10-30 齐鲁天和惠世制药有限公司 一种盐酸文拉法辛中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2462736A (en) 1944-08-09 1949-02-22 Du Pont Preparation of n,n' dimethylethanolamine
US4535186A (en) 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
US6350912B1 (en) 2001-02-28 2002-02-26 Council Of Scientific And Industrial Research One pot process for the preparation of 1-[2-dimethylamino-(4-methoxyphenyl)-ethyl]cyclohexanol

Also Published As

Publication number Publication date
CA2482569C (en) 2010-11-09
DE60229789D1 (de) 2008-12-18
AU2002345346B2 (en) 2009-12-03
EP1490325B1 (de) 2008-11-05
AU2002345346A1 (en) 2003-10-08
EP1490325A1 (de) 2004-12-29
CA2482569A1 (en) 2003-10-02
US7026513B2 (en) 2006-04-11
US20050228198A1 (en) 2005-10-13
WO2003080560A1 (en) 2003-10-02
NZ535548A (en) 2005-12-23

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Legal Events

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