ATE4116T1 - Reinigung von menschlichem wachstumshormon. - Google Patents
Reinigung von menschlichem wachstumshormon.Info
- Publication number
- ATE4116T1 ATE4116T1 AT80302822T AT80302822T ATE4116T1 AT E4116 T1 ATE4116 T1 AT E4116T1 AT 80302822 T AT80302822 T AT 80302822T AT 80302822 T AT80302822 T AT 80302822T AT E4116 T1 ATE4116 T1 AT E4116T1
- Authority
- AT
- Austria
- Prior art keywords
- growth hormone
- human growth
- purification
- chromatography
- hydrophobic
- Prior art date
Links
- 102000002265 Human Growth Hormone Human genes 0.000 title abstract 3
- 108010000521 Human Growth Hormone Proteins 0.000 title abstract 3
- 239000000854 Human Growth Hormone Substances 0.000 title abstract 3
- 238000000746 purification Methods 0.000 title 1
- 206010062767 Hypophysitis Diseases 0.000 abstract 1
- 239000003463 adsorbent Substances 0.000 abstract 1
- 239000011543 agarose gel Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 238000004191 hydrophobic interaction chromatography Methods 0.000 abstract 1
- 229910017053 inorganic salt Inorganic materials 0.000 abstract 1
- 210000003635 pituitary gland Anatomy 0.000 abstract 1
- 229920005990 polystyrene resin Polymers 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/854—Glands
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10680879A JPS5630925A (en) | 1979-08-21 | 1979-08-21 | Purification of human growth hormone |
EP80302822A EP0026045B1 (de) | 1979-08-21 | 1980-08-15 | Reinigung von menschlichem Wachstumshormon |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE4116T1 true ATE4116T1 (de) | 1983-07-15 |
Family
ID=14443143
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT80302822T ATE4116T1 (de) | 1979-08-21 | 1980-08-15 | Reinigung von menschlichem wachstumshormon. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4332717A (de) |
EP (1) | EP0026045B1 (de) |
JP (1) | JPS5630925A (de) |
AT (1) | ATE4116T1 (de) |
DE (1) | DE3064133D1 (de) |
DK (1) | DK357880A (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4371462A (en) * | 1982-01-21 | 1983-02-01 | Genex Corporation | Method for purification of anterior pituitary hormones |
US4775622A (en) * | 1982-03-08 | 1988-10-04 | Genentech, Inc. | Expression, processing and secretion of heterologous protein by yeast |
US4859600A (en) * | 1983-04-25 | 1989-08-22 | Genentech, Inc. | Recombinant procaryotic cell containing correctly processed human growth hormone |
US4568488A (en) * | 1984-01-11 | 1986-02-04 | Lee Huang Sylvia | Reverse immunoaffinity chromatography purification method |
US4612367A (en) * | 1985-04-08 | 1986-09-16 | Eli Lilly And Company | Process for purifying growth hormone-like materials |
US5079230A (en) * | 1988-09-12 | 1992-01-07 | Pitman-Moore, Inc. | Stable bioactive somatotropins |
US5215908A (en) * | 1989-06-13 | 1993-06-01 | Genencor International, Inc. | Process for recovery and purification of chymosin |
US5043431A (en) * | 1989-09-11 | 1991-08-27 | Codon | Method and apparatus for the production of TGF-β |
US5266477A (en) * | 1990-02-02 | 1993-11-30 | Pitman-Moore, Inc. | Monoclonal antibodies which differentiate between native and modified porcine somatotropins |
KR970006498A (ko) * | 1995-07-31 | 1997-02-21 | 유충식 | 활성형 인성장호르몬의 정제 방법 |
US5760187A (en) * | 1996-02-22 | 1998-06-02 | Mitsui Toatsu Chemicals, Inc. | Purification process of a human growth hormone |
WO2005073732A2 (en) * | 2004-01-23 | 2005-08-11 | Amgen Inc. | Lc/ms method of analyzing high molecular weight proteins |
WO2006051554A1 (en) * | 2004-11-09 | 2006-05-18 | Usv Limited | A novel process for purification of human growth harmone |
US8080391B2 (en) * | 2004-12-22 | 2011-12-20 | Ambrx, Inc. | Process of producing non-naturally encoded amino acid containing high conjugated to a water soluble polymer |
MX2008015263A (es) * | 2006-06-02 | 2008-12-17 | Wyeth Corp | Uso de proteinas y pepetidos de la superfamilia del factor beta transformador de crecimiento para purificacion y metodos terapeuticos. |
US9238878B2 (en) | 2009-02-17 | 2016-01-19 | Redwood Bioscience, Inc. | Aldehyde-tagged protein-based drug carriers and methods of use |
US20100222560A1 (en) | 2009-03-02 | 2010-09-02 | Zymo Research Corporation | Universal column |
AU2012205301B2 (en) | 2011-01-14 | 2017-01-05 | Redwood Bioscience, Inc. | Aldehyde-tagged immunoglobulin polypeptides and method of use thereof |
US11208632B2 (en) | 2016-04-26 | 2021-12-28 | R.P. Scherer Technologies, Llc | Antibody conjugates and methods of making and using the same |
CN114213525B (zh) * | 2021-12-30 | 2024-05-28 | 科兴生物制药股份有限公司 | 一种生长激素的纯化方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3409605A (en) * | 1965-06-15 | 1968-11-05 | American Cyanamid Co | Concentration and purification of growth factor-placental origin (human) |
US4006059A (en) * | 1974-07-29 | 1977-02-01 | Purdue Research Foundation | Hydrophobic noncovalent binding of proteins to support materials |
US4000098A (en) * | 1974-08-16 | 1976-12-28 | Palo Alto Medical Research Foundation | Separation of proteins by hydrophobic adsorption |
DK144731C (da) * | 1976-07-30 | 1982-10-18 | Nordisk Insulinlab | Fremgangsmaade til isolering af proteinhormoner stammende fra humant hypofysevaev |
-
1979
- 1979-08-21 JP JP10680879A patent/JPS5630925A/ja active Pending
-
1980
- 1980-08-15 DE DE8080302822T patent/DE3064133D1/de not_active Expired
- 1980-08-15 AT AT80302822T patent/ATE4116T1/de not_active IP Right Cessation
- 1980-08-15 EP EP80302822A patent/EP0026045B1/de not_active Expired
- 1980-08-20 DK DK357880A patent/DK357880A/da not_active Application Discontinuation
- 1980-08-21 US US06/180,178 patent/US4332717A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPS5630925A (en) | 1981-03-28 |
DE3064133D1 (en) | 1983-08-18 |
EP0026045B1 (de) | 1983-07-13 |
EP0026045A1 (de) | 1981-04-01 |
US4332717A (en) | 1982-06-01 |
DK357880A (da) | 1981-02-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |