ATE405533T1 - Verfahren zur ä11cü-radiomarkierung von phenthiazin und phenothiazinartige verbindungen - Google Patents
Verfahren zur ä11cü-radiomarkierung von phenthiazin und phenothiazinartige verbindungenInfo
- Publication number
- ATE405533T1 ATE405533T1 AT04768696T AT04768696T ATE405533T1 AT E405533 T1 ATE405533 T1 AT E405533T1 AT 04768696 T AT04768696 T AT 04768696T AT 04768696 T AT04768696 T AT 04768696T AT E405533 T1 ATE405533 T1 AT E405533T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- sub
- group
- phenothiazine
- radiolabelling
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/20—[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0322756.8A GB0322756D0 (en) | 2003-09-29 | 2003-09-29 | Methods of chemical synthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE405533T1 true ATE405533T1 (de) | 2008-09-15 |
Family
ID=29287034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04768696T ATE405533T1 (de) | 2003-09-29 | 2004-09-27 | Verfahren zur ä11cü-radiomarkierung von phenthiazin und phenothiazinartige verbindungen |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20060275209A1 (de) |
| EP (1) | EP1667947B1 (de) |
| JP (1) | JP2007508282A (de) |
| CN (2) | CN101172162A (de) |
| AT (1) | ATE405533T1 (de) |
| AU (1) | AU2004276071B2 (de) |
| CA (1) | CA2540827A1 (de) |
| DE (1) | DE602004016010D1 (de) |
| ES (1) | ES2313063T3 (de) |
| GB (1) | GB0322756D0 (de) |
| HK (1) | HK1087394A1 (de) |
| PL (1) | PL1667947T3 (de) |
| SI (1) | SI1667947T1 (de) |
| WO (1) | WO2005030676A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9506197D0 (en) | 1995-03-27 | 1995-05-17 | Hoffmann La Roche | Inhibition of tau-tau association. |
| GB0100119D0 (en) | 2001-01-03 | 2001-02-14 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
| GB0101049D0 (en) | 2001-01-15 | 2001-02-28 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
| GB0106953D0 (en) | 2001-03-20 | 2001-05-09 | Univ Aberdeen | Neufofibrillary labels |
| GB0117326D0 (en) | 2001-07-16 | 2001-09-05 | Univ Aberdeen | Napthoquinone-type inhibitors of protein aggregation |
| CN101084204B (zh) | 2004-09-23 | 2012-12-05 | 卫思道制药有限公司 | 包括亚甲蓝(mtc)在内的二氨基吩噻嗪鎓化合物的化学合成和纯化方法 |
| ES2349322T7 (es) | 2006-03-29 | 2019-10-17 | Wista Lab Ltd | Sales de 3,7-diamino-10H-fenotiazina y su utilización |
| WO2007110630A1 (en) | 2006-03-29 | 2007-10-04 | Wista Laboratories Ltd. | Thioninium compounds and their use |
| US8263589B2 (en) | 2006-03-29 | 2012-09-11 | Wista Laboratories Ltd. | Inhibitors of protein aggregation |
| PL2057136T3 (pl) | 2006-07-11 | 2013-10-31 | Wista Lab Ltd | Sposoby syntezy i/lub oczyszczania związków diaminofenotiazynowych |
| HUE025199T2 (en) | 2007-10-03 | 2016-01-28 | Wista Lab Ltd | Therapeutic use of diaminophenothiazines |
| PL3378856T3 (pl) | 2009-09-24 | 2021-05-31 | Wista Laboratories Ltd. | Krystaliczne hydraty chlorku metylotioniny |
| CN103379901B (zh) | 2010-11-30 | 2018-04-03 | 维斯塔实验室有限公司 | 含有氯化甲基息奥宁的配方 |
| KR101888713B1 (ko) | 2011-02-11 | 2018-08-14 | 위스타 레보레이토리스 리미티드 | 페노티아진 디아미늄 염 및 이의 용도 |
| US20130315825A1 (en) * | 2012-05-03 | 2013-11-28 | Washington University | Tricyclic heteroaromatic compounds as alpha-synuclein ligands |
| CA2929116C (en) * | 2013-10-31 | 2024-02-27 | Beth Israel Deaconess Medical Center | Near-infrared fluorescent contrast bioimaging agents and methods of use thereof |
| US11001562B2 (en) | 2013-10-31 | 2021-05-11 | Beth Israel Deaconess Medical Center | Near-infrared fluorescent nerve contrast agents and methods of use thereof |
| GB201512678D0 (en) | 2015-07-20 | 2015-08-26 | Wista Lab Ltd | Methods of chemical synthesis |
| CN109796465B (zh) * | 2017-11-16 | 2020-07-14 | 华中科技大学同济医学院附属协和医院 | 靶向pet显像化合物、包含该化合物的显象剂及其制备方法和用途 |
| US20210011008A1 (en) * | 2019-07-09 | 2021-01-14 | Vanderbilt University | Amyloid-binding compounds and methods of use thereof |
| CN115304633B (zh) * | 2022-07-20 | 2023-12-26 | 山西大学 | 一种无重原子光动力光敏剂及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000344685A (ja) * | 1999-03-26 | 2000-12-12 | Bf Kenkyusho:Kk | アズールａ類似化合物によるアミロイドが蓄積する疾患の画像診断プローブおよびそれを含む画像診断用組成物 |
| JP4275819B2 (ja) * | 1999-09-17 | 2009-06-10 | 飯田 秀博 | デメチルラクロプライドの非求核性酸塩およびこれを用いる［ｃ−１１］ラクロプライドの製造法 |
| GB0106953D0 (en) * | 2001-03-20 | 2001-05-09 | Univ Aberdeen | Neufofibrillary labels |
| GB0113121D0 (en) * | 2001-05-30 | 2001-07-18 | Univ Leeds | Biologically active photosensitisers |
-
2003
- 2003-09-29 GB GBGB0322756.8A patent/GB0322756D0/en not_active Ceased
-
2004
- 2004-09-27 US US10/573,882 patent/US20060275209A1/en not_active Abandoned
- 2004-09-27 PL PL04768696T patent/PL1667947T3/pl unknown
- 2004-09-27 ES ES04768696T patent/ES2313063T3/es not_active Expired - Lifetime
- 2004-09-27 CA CA002540827A patent/CA2540827A1/en not_active Abandoned
- 2004-09-27 SI SI200430921T patent/SI1667947T1/sl unknown
- 2004-09-27 CN CNA2007101666344A patent/CN101172162A/zh active Pending
- 2004-09-27 WO PCT/GB2004/004153 patent/WO2005030676A1/en active IP Right Grant
- 2004-09-27 AU AU2004276071A patent/AU2004276071B2/en not_active Ceased
- 2004-09-27 EP EP04768696A patent/EP1667947B1/de not_active Expired - Lifetime
- 2004-09-27 JP JP2006530567A patent/JP2007508282A/ja active Pending
- 2004-09-27 CN CN2004800350118A patent/CN1886353B/zh not_active Expired - Fee Related
- 2004-09-27 AT AT04768696T patent/ATE405533T1/de not_active IP Right Cessation
- 2004-09-27 DE DE602004016010T patent/DE602004016010D1/de not_active Expired - Lifetime
-
2006
- 2006-08-25 HK HK06109484A patent/HK1087394A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE602004016010D1 (de) | 2008-10-02 |
| US20060275209A1 (en) | 2006-12-07 |
| ES2313063T3 (es) | 2009-03-01 |
| WO2005030676A1 (en) | 2005-04-07 |
| EP1667947B1 (de) | 2008-08-20 |
| JP2007508282A (ja) | 2007-04-05 |
| CN1886353B (zh) | 2010-06-02 |
| CA2540827A1 (en) | 2005-04-07 |
| CN101172162A (zh) | 2008-05-07 |
| SI1667947T1 (sl) | 2009-02-28 |
| HK1087394A1 (en) | 2006-10-13 |
| AU2004276071A1 (en) | 2005-04-07 |
| EP1667947A1 (de) | 2006-06-14 |
| GB0322756D0 (en) | 2003-10-29 |
| PL1667947T3 (pl) | 2009-01-30 |
| CN1886353A (zh) | 2006-12-27 |
| AU2004276071B2 (en) | 2011-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |