ATE395419T1 - Neue mapk kinase - Google Patents
Neue mapk kinaseInfo
- Publication number
- ATE395419T1 ATE395419T1 AT98929833T AT98929833T ATE395419T1 AT E395419 T1 ATE395419 T1 AT E395419T1 AT 98929833 T AT98929833 T AT 98929833T AT 98929833 T AT98929833 T AT 98929833T AT E395419 T1 ATE395419 T1 AT E395419T1
- Authority
- AT
- Austria
- Prior art keywords
- kinase
- dna
- mapk
- mentioned
- same
- Prior art date
Links
- 108091054455 MAP kinase family Proteins 0.000 title abstract 3
- 102000043136 MAP kinase family Human genes 0.000 title abstract 3
- 108020004414 DNA Proteins 0.000 abstract 5
- 102000004232 Mitogen-Activated Protein Kinase Kinases Human genes 0.000 abstract 4
- 108090000744 Mitogen-Activated Protein Kinase Kinases Proteins 0.000 abstract 4
- 108020004511 Recombinant DNA Proteins 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- GOZMBJCYMQQACI-UHFFFAOYSA-N 6,7-dimethyl-3-[[methyl-[2-[methyl-[[1-[3-(trifluoromethyl)phenyl]indol-3-yl]methyl]amino]ethyl]amino]methyl]chromen-4-one;dihydrochloride Chemical compound Cl.Cl.C=1OC2=CC(C)=C(C)C=C2C(=O)C=1CN(C)CCN(C)CC(C1=CC=CC=C11)=CN1C1=CC=CC(C(F)(F)F)=C1 GOZMBJCYMQQACI-UHFFFAOYSA-N 0.000 abstract 1
- 101000950669 Homo sapiens Mitogen-activated protein kinase 9 Proteins 0.000 abstract 1
- 108010055717 JNK Mitogen-Activated Protein Kinases Proteins 0.000 abstract 1
- 102000019145 JUN kinase activity proteins Human genes 0.000 abstract 1
- 102100037809 Mitogen-activated protein kinase 9 Human genes 0.000 abstract 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 108010052621 fas Receptor Proteins 0.000 abstract 1
- 102000018823 fas Receptor Human genes 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/12—Dual-specificity kinases (2.7.12)
- C12Y207/12002—Mitogen-activated protein kinase kinase (2.7.12.2), i.e. MAPKK or MEK1 or MEK2
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19320797 | 1997-07-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE395419T1 true ATE395419T1 (de) | 2008-05-15 |
Family
ID=16304090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98929833T ATE395419T1 (de) | 1997-07-03 | 1998-07-03 | Neue mapk kinase |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6465618B1 (de) |
| EP (1) | EP1008650B1 (de) |
| JP (1) | JP4024313B2 (de) |
| AT (1) | ATE395419T1 (de) |
| AU (1) | AU7937398A (de) |
| CA (1) | CA2296070C (de) |
| DE (1) | DE69839484D1 (de) |
| WO (1) | WO1999001559A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6943000B2 (en) | 1997-10-03 | 2005-09-13 | University Of Massachusetts | JNK3 modulators and methods of use |
| AU2002336475A1 (en) * | 2001-09-12 | 2003-03-24 | The Regents Of The University Of California | Methods of ameliorating arthritis by modulating jnk signalsome activity |
| US7195894B2 (en) * | 2002-06-28 | 2007-03-27 | Daiichi Pharmaceutical Co., Ltd. | MKK7 activation inhibitor |
| WO2004043976A2 (en) * | 2002-11-12 | 2004-05-27 | Warner-Lambert Company Llc | Mkk7gamma1 nucleic acids and polypeptides |
| ATE531725T1 (de) | 2007-02-27 | 2011-11-15 | Nuclea Biomarkers Llc | Verfahren zur vorhersage ob nsclc-patienten auf eine behandlung mit einem egfr-tk-hemmer ansprechen |
| GB201017520D0 (en) * | 2010-10-15 | 2010-12-01 | Sense Proteomic Ltd | Biomarkers |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6136596A (en) * | 1995-05-19 | 2000-10-24 | University Of Massachusetts | Cytokine-, stress-, and oncoprotein-activated human protein kinase kinases |
| GB9717416D0 (en) * | 1997-08-19 | 1997-10-22 | Medical Res Council | Polypeptides,polynucleotides and uses thereof |
| US6492112B1 (en) * | 1997-12-31 | 2002-12-10 | Chiron Corporation | Mitogen-activated protein kinase kinase 7 (MKK7) |
-
1998
- 1998-07-03 JP JP50688599A patent/JP4024313B2/ja not_active Expired - Fee Related
- 1998-07-03 WO PCT/JP1998/003016 patent/WO1999001559A1/ja active IP Right Grant
- 1998-07-03 AT AT98929833T patent/ATE395419T1/de not_active IP Right Cessation
- 1998-07-03 AU AU79373/98A patent/AU7937398A/en not_active Abandoned
- 1998-07-03 DE DE69839484T patent/DE69839484D1/de not_active Expired - Lifetime
- 1998-07-03 EP EP98929833A patent/EP1008650B1/de not_active Expired - Lifetime
- 1998-07-03 US US09/446,754 patent/US6465618B1/en not_active Expired - Fee Related
- 1998-07-03 CA CA002296070A patent/CA2296070C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2296070C (en) | 2003-12-30 |
| EP1008650B1 (de) | 2008-05-14 |
| EP1008650A4 (de) | 2005-04-06 |
| CA2296070A1 (en) | 1999-01-14 |
| DE69839484D1 (de) | 2008-06-26 |
| WO1999001559A1 (fr) | 1999-01-14 |
| JP4024313B2 (ja) | 2007-12-19 |
| AU7937398A (en) | 1999-01-25 |
| EP1008650A1 (de) | 2000-06-14 |
| US6465618B1 (en) | 2002-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |